| DC8342 |
EW-7197
Featured
|
EW-7197 is a potent ALK5 inhibitor. EW-7197 showed potent in vivo anti-metastatic activity, indicating its potential for use as an anti-cancer therapy. |
|
| DC11634 |
EX-229
Featured
|
EX229 is a small molecule AMPK activator that dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing complexes at 50 uM |
|
| DC7578 |
Exatecan (Mesylate)
Featured
|
Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. |
|
| DC21005 |
EXEL-0346 |
EXEL-0346 (EXEL0346) is a novel potent, orally active Glucosylceramide synthase (GCS) inhibitor with IC50 of 2 nM. |
|
| DC8260 |
Exemestane(FCE 24304)
Featured
|
Exemestane(FCE 24304) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively. |
|
| DC22518 |
Exenatide |
Exenatide (Exendin-4) is a 39-aa peptide, highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM. |
|
| DC22517 |
Exendin-4 acetate
Featured
|
Exenatide acetate (Exendin-4 acetate) is the acetate of Exenatide, which is highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM.. |
|
| DC9532 |
ADH-1 trifluoroacetate
Featured
|
Exherin (ADH-1) trifluoroacetate is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities; selectively and competitively binds to and blocks N-cadherin.
|
|
| DC10905 |
Exo1
Featured
|
Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 µM). |
|
| DC7204 |
Ezatiostat(TER199; TLK199)
Featured
|
Ezatiostat(TER199; TLK199) is a glutathione analog inhibitor of glutathione S-transferase (GST) P1-1. |
|
| DCAPI1084 |
Ezetimibe (Zetia)
Featured
|
Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. |
|
| DC20377 |
EZH2-IN-3 |
EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively. |
|
| DC10679 |
EZM2302
Featured
|
EZM2302 (GSK3359088) is the first potent and selective inhibitor of CARM1 enzymatic activity that exhibits anti-proliferative effects both in vitro and in vivo,in biochemical assays (IC50=6nM) with broad selectivity against histone methyltransferases. |
|
| DC9821 |
Ezutromid
Featured
|
Ezutromid is a novel Small utrophin's translation modulator with EC50 of 0.4 uM . |
|
| DC10838 |
F1063-0967
Featured
|
F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. |
|
| DC20379 |
Factor D inhibitor 6 |
Factor D inhibitor 6 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 30 nM. |
|
| DC23545 |
Factor D inhibitor 7 |
Factor D inhibitor 7 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 50 nM. |
|
| DC21899 |
Fadaltran |
Fadaltran is a α2-adrenoreceptor antagonist.. |
|
| DC11329 |
Fadrozole (hydrochloride)
Featured
|
Fadrozole is a non-steroidal aromatase inhibitor (IC50s = 5 and 1.4 nM for human placental and rat ovarian microsomal aromatase, respectively). |
|
| DC21900 |
FAK inhibitor 5 |
FAK inhibitor 5 is the first highly potent, selective irreversible inhibitor of the FAK kinase with IC50 of 0.6 nM. |
|
| DCAPI1576 |
Falecalcitriol |
Falecalcitriol |
|
| DCAPI1011 |
Famciclovir (Famvir) |
Famciclovir (Famvir) |
|
| DC21650 |
Famitinib |
Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET. |
|
| DC9073 |
Famotidine |
Famotidine is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. |
|
| DC10910 |
Fantofarone
Featured
|
Fantofarone is a calcium channel blocker. |
|
| DC10382 |
Farampator
Featured
|
Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. |
|
| DC9350 |
Faropenem daloxate |
Faropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.
|
|
| DC20380 |
Faropenem |
Faropenem is an orally active beta-lactam antibiotic with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes. |
|
| DC24118 |
C75
Featured
|
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM). |
|
| DC11864 |
Fascaplysin (chloride)|CDK4 inhibitor
Featured
|
Fascaplysin is a potent, selective ATP-competitive CDK4 inhibitor (IC50 = 350 nM). |
|
