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Cat. No. Product name CAS No.
DCC4030 Pcpma-(1r,2r)-30q

Novel potent and selective dopamine D3R partial agonist

DCC4031 Pcpma-(1s,2s)-22e

Novel potent dopamine D3R antagonist

DCC4032 Pcsk9 Modulator

Novel modulator of proprotein convertase subtilisin kexin like type 9 (PCSK9)

DCC4033 Pcsk9-in-4d

Novel PCSK9 mRNA translation inhibitor

DCC4034 Pcsk9-in-4g

Novel PCSK9 mRNA translation inhibitor

DCC4035 Pcsk9-in-8b

Novel liver-targeted inhibitor of ribosomal synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9)

DCC4036 Pd-1 Inhibitor 16

Novel inhibitor of PD-I/PD-L1 interaction to be used as a negative immune checkpoint regulatory and antineoplastic agent

2005454-12-4
DCC4037 Pd-1/pd-l1 Antagonist D2

Novel potent PD-1/PD-L1 antagonist (IC50 of 16.17 nM), activating the antitumor immunity of T cells efficiently in PBMCs

DCC4038 Pd-1/pd-l1 Inhibitor 17

Novel bifunctional inhibitor of PD-1/PD-L1 interactions, promoting dimerization, internalization, and degradation of PD-L1, suppressing tumor growth in vivo by activating antitumor immunity

DCC4039 Pd-1/pd-l1 Inhibitor A30

Novel Potent Inhibitor of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction

DCC4040 Pd-1/pd-l1 Inhibitor Ch1

Novel inhibitor of PD-1/PD-L1 (IC 50 value of 56.58 nM), dose-dependently promoting HepG2 cell death in a co-culture model of HepG2/hPD-L1 and Jurkat T cells, effectively inhibiting tumor growth (TGI of 76.4% at 90 mg/kg) in an immune checkpoint humanized

DCC4041 Pd-1/pd-l1 Inhibitor P18

Novel potent programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor (IC50 9.1 nM)

DCC4042 Pd-128907 Hydrochloride

Selective D3 dopamine receptor agonist

123594-64-9
DCC4043 Pd-151242

Selective antagonist for human ETA receptors

155561-67-4
DCC4044 Pd160170

Neuropeptide Y Y1 receptor antagonist

181468-88-2
DCC4045 Pd-160725 Isethionate

AMPA receptor antagonist

1262769-92-5
DCC4046 Pd-161989 Isethionate

AMPA receptor antagonist

1262770-05-7
DCC4047 Pd-174494

Novel, potent, and selective NR1/2B NMDA receptor antagonist

193359-26-1
DCC4048 P-d1ago

Novel cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors

DCC4049 Pd26-tl07

Novel selective inhibitor of STAT3 phosphorylation, binding to the SH2 domain of STAT3, exhibiting remarkable antiproliferative activity against three cancer cell lines (HCT-116, SW480 and MDA-MB-231)

DCC4050 pda-66

Novel inducer of mitotic arrest and apoptosis in human progenitor and cancer cells

1613633-78-5
DCC4051 Pdd4091

Novel G6PD inhibitor

DCC4052 Pde5-in-42

Potent and selective second-generation phosphodiesterase type 5 (PDE5) inhibitor

936449-28-4
DCC4053 Pde7 Inhibitor S14

Novel cell-permeable PDE7 inhibitor, targeting the cyclic adenosine monophosphate (cAMP)/cAMP-response element binding protein (CREB) pathway, exerting neuroprotection in an Alzheimer's disease (AD) model

18741-24-7
DCC4054 Pde9-in-16

Novel selective PDE9 inhibitor with strong antioxidant activity, inhibiting Aβ aggregation as potential candidates for the treatment of Alzheimer’s disease

DCC4055 Pde9-in-2

Novel Potent, Selective, and Orally Bioavailable Inhibitor against Phosphodiesterase-9 (PDE9)

DCC4056 P-decylaminophenol

Novel inhibitor of melanogenesis

23227-12-5
DCC4057 Pdf Inhibitor M-2

Novel Peptide Deformylase (PDF) Inhibitor

DCC4058 Pdi-in-p1

Protein disulfide isomerase (PDI) inhibitor

1461648-55-4
DCC4059 Pd-l1 Degrader F4

Novel PD-L1 degrader, showing 66.99% degradation activity at 20 μM with no calcium blocking effect, strengthening the T cell-mediated killing of tumor cells

DCC4060 Pd-l1 Degrader P22

Novel PROTAC dual inhibitor and degrader of PD-L1, inhibiting PD-1/PD-L1 interaction with IC50 of 39.2 nM in an HTRF binding assay

2447066-37-5
DCC4061 Pd-l1 Inhibitor L7

Novel Potent PD-L1 Inhibitor (IC50 1.8 nM), binding to human PD-L1 (hPD-L1) with a KD value of 3.34 nM, without showing any binding to hPD-1, blocking PD-1/PD-L1 interaction with an EC50 value of 375 nM

DCC4062 Pdsinh-c01

Novel pendrin inhibitor, inhibiting Cl-/anion exchange mediated by mouse pendrin without affecting other major kidney tubule transporters

DCC4063 Peg-vtx

Novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML)

DCC4064 Pelorol

Activator of SHIP-1

287974-44-1
DCC4065 pemedolac

Cyclooxygenase Inhibitor and Prostagladin Synthase Inhibitor

103024-44-8
DCC4066 Penb-l-glutamate

Novel caged glutamate

DCC4067 Penclomedine

Antineoplastic agent, alkylating and crosslinking DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis

108030-77-9
DCC4068 Penicillic Acid

Mycotoxin with antibiotic and carcinogenic activity

90-65-3
DCC4069 penicillin K

Antibiotic, a natural penicillin, synthesized in vitro by incubating (S-octanoyl)glutathione, 6-APA and AT

525-97-3
DCC4070 Penindolone

Novel potent and broad-spectrum anti-influenza A virus (anti-IAV) activities with low risk of inducing drug resistance

DCC4071 Pentamidine Dimesylate

Inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53] in malignant melanoma (MM), restoring p53 tumor suppressor activity in vivo

6823-79-6
DCC4072 Peptide 1018

Innate defense regulator, target stringent response-controlled virulence in a Pseudomonas aeruginosa murine cutaneous infection model

DCC4073 Peptide 4f

ApoA-I/HDL mimetic peptide, efficiently crossing the blood-brain barrier and modulating amyloid beta distribution between brain and plasma

DCC4074 Peptide P9r

Broad-spectrum virus- and host-targeting peptide, inhibiting coronaviruses and other respiratory viruses

DCC4075 Pergolide Mesylate

Agonist of dopamine receptor subtypes D1 and D2

66104-23-2
DCC4076 Peridinin

Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation

33281-81-1
DCC4077 Perindopril

Non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor

82834-16-0
DCC4078 Pet-16

Novel allosteric inhibitor of E. coli Hsp70 (DnaK) and human Hsp70 proteins

34387-64-9
DCC4079 Pex14-pex5 Inhibitor-5

First Inhibitor of PEX14-PEX5 Protein-Protein Interaction (PPI) with Trypanocidal Activity

DCC4080 Pf-03084014

Novel γ-secretase inhibitor

865773-15-5
DCC4081 Pf-03671148

Dose dependent inhibitor of multiple fibrotic genes

1378524-25-4
DCC4082 Pf-04363467 Hydrochloride

Selective dopamine D3/D2 receptor antagonist

2040055-81-8
DCC4083 Pf-04671536 Hydrochloride

Novel potent and selective PDE8B/8A inhibitor

1305116-67-9
DCC4084 pf-04859989

Irriversible inhibitor of kynurenine amino transferase II (KAT II)

34783-48-7
DCC4085 Pf-05109794

Novel selective hTRPV4 Antagonist (hTRPV4 IC50 49nM; rTRPV4 IC50 1,150nM)

DCC4086 Pf-05214030

Novel potent TRPV4 antagonist (hTRPV4 IC50 4nM; rTRPV4 IC50 27nM)

1669444-50-1
DCC4087 Pf-06371900

Novel potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor

1622291-81-9
DCC4088 Pf-06424439 Mesylate Featured

Potent and selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2)

1469284-79-4
DCC4089 Pf-06655075

Novel non-brain-penetrant long-acting peptide oxytocin (OT) receptor agonist with increased selectivity for the OT receptor and significantly increased pharmacokinetic stability

DCC4090 Pf-06745013

Novel potent and selective inhibitor of MAP4K4

DCC4091 Pf-06756394

Novel tyrosine residues probe, rationally targeting active site

DCC4092 Pf-06758955 Hydrochloride

Novel potent and selective inhibitor of MAP4K4

DC30002 PF-06835919 Featured

PF-06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF-06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to further elucidate the effect of KHK inhibition on these metabolic disorders.

2102501-84-6
DCC4094 Pf-06843195 Prodrug

Novel prdrug of PF-06843195, a potent PI3Kα-selective inhibitor

DCC4095 Pf-06939999

Novel SAM Competitive PRMT5 Inhibitor, Demonstrating Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance

DCC4096 Pf1070a

Natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein

146556-41-4
DCC4097 Pf-184563

Potent, selective non-peptidic antagonist of the V1a receptor

748806-39-5
DCC4098 Pf-3604861

Novel dual H3/4 histamine receptor antagonist

DCC4099 Pf-3837

Highly selective, extremely potent Mps1 kinase inhibitor

DCC4100 Pf-4522654

Potent and selective 5-HT2C receptor agonist

1065109-28-5
DCC4101 Pf-5177624

Selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells

1350821-45-2
DCC4102 Pf-543 Hydrochloride Featured

Novel, potent and specific inhibitor of sphingosine kinase-1 (SphK1)

1706522-79-3
DCC4103 pf-5466

Antimalarial, actively against Plasmodium liver stages

1353762-98-7
DCC4104 Pf-562271 Tosylate

Potent, ATP-competitive, reversible inhibitor of FAK

939791-40-9
DCC4105 Pf-562771

Novel potent and selective inhibitor of the activation-loop mutant Kit phosphorylation and tumor growth

834894-21-2
DCC4106 Pf-68742

Novel Entry Inhibitor of both CCR5- and CXCR4-Tropic Strains of Human Immunodeficiency Virus Type 1 (HIV-1), Targeting a Novel Site on gp41

DCC4107 Pf-7006

Highly selective, extremely potent Mps1 kinase inhibitor

DCC4108 Pf-alkyne

Novel fluorophosphonate-based probe, specifically and covalently reacts with the tyrosine-111 residue of the Schistosoma japonicum GST (sjGST) tag, rapidly and site-selectively immobilizes sjGST fusion proteins

DCC4109 Pf-cbp/brd4

Novel dual CBP/p300 and BRD4 bromodomain inhibitor, downregulating IL-6, IL-ß and IFN-ß in macrophages

1962928-22-8
DCC4110 Pfi-7n

Negative control for PFI-7 (GLXC012596)

DCC4111 Pfkrs1-in-5

Novel selective inhibitor of both Plasmodium and Cryptosporidium lysyl-tRNA synthetase, clearing parasites from mouse models of malaria and cryptosporidiosis infection.

DCC4112 Pfn1-in-c1

Novel inhibitor of Profilin1 (Pfn1), reducing the overall level of cellular filamentous (F)-actin, slowing EC migration and proliferation, and inhibiting the angiogenic ability of EC both in vitro and ex vivo

919010-46-1
DCC4113 Pfn1-in-c2

Novel inhibitor of Profilin1 (Pfn1), reducing the overall level of cellular filamentous (F)-actin, slowing EC migration and proliferation, and inhibiting the angiogenic ability of EC both in vitro and ex vivo

919010-22-3
DCC4114 Pg490-88

Water soluble derivative pro-drug of PG490 (triptolide)

195883-06-8
DCC4115 Pg-928310

Novel anti-HIF-1alpha agent

514218-36-1
DCC4116 Pg97-269 Tfa Salt

Potent and selective antagonist of the VIP1 receptor, inhibiting competitively effect of VIP on the VIP1 receptor mediated stimulation of adenylate cyclase activity with Ki values respectively of 15 ± 5 nM and 2 ± 1 nM for the rat and human VIP1 receptor

202463-00-1
DCC4117 Pgam1 Inhibitor Kh2

Novel allosteric PGAM1 inhibitor, showing efficacious in multiple preclinical models of pancreatic ductal adenocarcinoma (PDAC), especially with high PGAM1 expression

DCC4118 Pgam1 Inhibitor Kh3

Novel allosteric PGAM1 inhibitor, showing efficacious in multiple preclinical models of pancreatic ductal adenocarcinoma (PDAC), especially with high PGAM1 expression

DCC4119 Pge-2946979

Novel potent matrix metalloproteinase (MMP) inhibitor, targeting MMPs 1, 3, 9, and 13 (24, 18, 1.9, and 1.3 nM, respectively)

380653-37-2
DCC4120 Pgmi-004a

Glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) inhibitor

1313738-90-7
DCC4122 pha-680626

Inhibitor of both Bcr-Abl tyrosine kinase and Aurora kinases

398493-74-8
DCC4123 Pha-e429

Selective ATP competitive ALK inhibitor

DCC4124 Phagocytosis Inhibitor

Inhibitor of phagocytosis, interacting with and inhibiting the activating Fc receptors on macrophages, inhibiting downstream signaling pathways driving Fc-mediated phagocytosis

683208-21-1
DCC4125 Phantasmidine

Natural nicotinic acetylcholine receptor agonist

DCC4126 Phar-095239

Novel COX-2 inhibitor

257289-81-9
DCC4127 Phencyclidine Hydrochloride

Inhibitor of NMDA receptors, used as a veterinary anesthetic, and briefly as a general anesthetic for humans

956-90-1
DCC4128 Phen-dc3

Selective ligand of a specific G-quadruplex conformation, interacting with the quadruplex through extensive

929895-45-4
DCC4129 phenoxodiol Diacetate

Prodrug of phenoxodiol

81267-66-5
DCC4130 Phenylarsine Oxide

Inhibitor of internalization of cell surface receptors and tyrosine phosphatases, with no effect on tyrosine kinase

637-03-6
DCC4131 phenylmethimazole

Blocker of dsRNA-induced IRF3 nuclear translocation and homodimerization; Inhibitor of lipopolysaccharide-mediated Toll-like receptor-4 signaling; Inhibitor of human pancreatic cancer

25433-13-0
DCC4132 Phnp-3

Novel selective α-syn ligand, exhibited the promising binding characteristics for α-syn aggregates (Ki = 0.52 nM)

DCC4133 Phoenixin-14

Novel neuropeptide, protecting human brain vascular endothelial cells against oxygen-glucose deprivation/reoxygenation (OGD/R)-induced inflammation and permeability, significantly ameliorating HFD-induced obesity and fatty liver, regulating pituitary gona

DCC4134 Phoenixin-20

Novel GPR173 agonist, promoting osteoblastic differentiation of MC3T3-E1 cells. stimulating mRNAs encoding hypothalamo-pituitary-gonadal hormones

DCC4135 Phomoxanthone A

Natural anti-tumor agent, showing strong apoptotic anticancer effects against platinum-resistant solid cancers

359844-69-2
DCC4136 Phosphatidylinositol

Potent antagonist of (H1N1)pdm09 infection, markedly suppressing cytopathic effects and attenuating viral gene expression in (H1N1)pdm09-infected MDCK cells

383907-36-6
DCC4137 phospho-sulindac

Sulindac derivative with promising anticancer activities

1421675-47-9
DCC4138 Phosphotyrosine

Inducer of platelet aggregation, playing a role in cellular signal transduction and possibly in cell growth control and carcinogenesis

21820-51-9
DCC4139 Photac-i-3

Novel photoswitchable BET bromodomain Degrader (PHOTAC)

2370997-94-5
DCC4140 Photoazolol-1

Novel potent photoswitchable antagonist for a precise spatiotemporal control of β2-adrenoceptors

DCC4141 Photogbi1

Novel photocontrol inhibitor of the voltage-gated proton channel Hv1

2146094-34-8
DCC4142 Photo-lenalidomide-acid

Functionalized photoswitchable cereblon ligand for Degraders

2363154-39-4
DCC4143 Photos1p

Novel photoswitchable sphingolipid probe, reversibly controlled S1P3-dependent pain hypersensitivity in mice and uniquely suited for the study of S1P biology in cultured cells and in vivo

DCC4144 Photosensitizer Pz I

Novel porphyrazine-based photodynamic anti-cancer agent, inducing immunogenic cell death

DCC4145 Photosensitizer Pz Iii

Novel porphyrazine-based photodynamic anti-cancer agent, inducing immunogenic cell death

DCC4146 Photosph

Novel photoswitchable sphingolipid probe

DCC4147 Phototrexate

Novel photoswitchable inhibitor of human dihydrofolate reductase

2268033-83-4
DCC4148 Phyllospadine

Natural flavonoidal alkaloid from the sea-grass Phyllosphadix iwatensis

76540-48-2
DCC4149 Physapubenolide

Natural cytotoxic withanolide antitumor agent, inducing apoptosis by decreasing mitochondrial membrane potential and elevating the Bax/Bcl-2 protein expression ratio

100217-92-3
DCC4150 Physodic Acid

Natural inhibitor of Wnt signaling, modulating β-catenin-dependent transcription

84-24-2
DCC4151 Pi-090

Platelet aggregation inhibitor

1389318-66-4
DCC4152 Pi-091

Platelet aggregation inhibitor

129051-63-4
DCC4153 Pi-2620

Novel Tau ligand, displaying high Tau binding, low MAO-A binding, high brain uptake, and fast and complete brain washout

DCC4154 Pi3k/akt/mtor-in-6be

Novel inhibitor of the PI3K/Akt/mTOR signaling pathways, activating P53 and inducing apoptosis

DCC4155 Pi3k/akt-in-c89

Novel Inhibitor of the PI3K-Akt Pathway, Inducing Autophagy of Female Germline Stem Cells

1195621-75-0
DCC4156 Pi3kd/v-in-01

Highly potent ATP-competitive PI3Kdelta/Vps34 dual inhibitor

1807551-44-5
DCC4157 Pi3ki1

Novel potent PI3K inhibitor with a modified omipalisib structure

DCC4158 Pi3k-in-s1

Novel PI3K inhibitor, synergizing with sorafenib in non-small cell lung cancer cells involving the Akt-S6 signaling.

DCC4159 Piboserod Hydrochloride

Selective 5-HT4 receptor antagonist

178273-87-5
DCC4160 Picrasidine N

Novel Subtype-Selective PPARbeta/delta Agonist

101219-62-9
DCC4161 Picumeterol

Potent and selective beta2-adrenoceptor agonist

130641-36-0
DCC4162 Pikamilone Sodium

Prodrug of GABA, used for treatment of neurogenic bladder in spinal and benign prostatic hyperplasia

62936-56-5
DCC4163 Pik-c98

Novel PI3K inhibitor, displaying potent preclinical activity against multiple myeloma

691388-62-2
DCC4164 Piloquinone

Natural activator of cryptic biosynthetic gene clusters (BGC), also acting as a potent inhibitor of monoamine oxidase B

25414-26-0
DCC4165 Pim-in-14j

Potent, highly selective, and orally bioavailable inhibitor of PIM-1 kinases

1036380-87-6
DCC4166 Pim-in-a47

Novel potent PIM inhibitor

DCC4167 Pinoxepin Hydrochloride

Antipsychotic agent

14008-46-9
DCC4168 Pip4k-in-a131

Inhibitor of PIP 4 Ks, efficiently killing transformed BJ cells, but not normal counterparts, displaying a strong selective lethality against Ras-activated or Ras-transformed cells

2055405-95-1
DCC4169 Pipequaline Hydrochloride

Partial agonist of benzodiazepine receptors

80221-58-5
DCC4170 Piperacetazine

Antipsychotic prodrug, most notably used for schizophrenia

3819-00-9
DCC4171 Piperazinomycin

Antifungal antibiotic, showing inhibitory activity against fungi and yeasts, especially against Trichophyton

83858-82-6
DCC4172 Piperidol B2

Novel potent in vitro and in vivo antifungal agent against azole-resistant Candida albicans

DCC4173 Piperneolignan A

Natural nitric oxide (NO) production inhibitor

DCC4174 Piroxicam-ß-cyclodextrin

NSAID with better gastrointestinal (GI) tolerability

121696-62-6
DCC4175 Pitofenone

Inhibitor of the acetylcholinesterase activity from bovine erythrocytes and electric eel

54063-52-4
DCC4176 Pixantrone

Inhibitor of topoisomerase II, intercalating into DNA and inducing topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity

144510-96-3
DCC4177 Pk5196

Potent ligand to target the Y220C pocket, stabilizing Y220C

DCC4178 Pkc-iota-in-19

Novel Protein Kinase C-iota (PKC-ι) Inhibitor, Binding Post-kinase Domain Residues

DCC4179 Pkcθ-in-41

Novel selective inhibitor of protein kinase Cθ (PKCθ)

DCC4180 Pkm2-in-8

Novel highly potent and selective PKM2 inhibitor, blocking PKM2 mitochondrial translocation under nutritional stress and inhibits tumor growth in vivo

DCC4181 Pks21272

Novel potent and specific β5i inhibitor

DCC4182 Pkumdl-ltq-301

Potent inhibitor of HipA toxin, inhibiting E. coli persistence

728886-01-9
DCC4183 Pladienolide B

mRNA splicing inhibitor

445493-23-2
DCC4184 Plafibride

Antilipidemic and antiplatelet agent

63394-05-8
DCC4185 Plap Inhibitor 16

Novel Potent and Specific Inhibitor of Placental Alkaline Phosphatase (PLAP; IC 50 = 32 nM), Targeting Tumor of the Female Reproductive Tract

DCC4186 Plasiatine

Novel Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2

DCC4187 Plaunotol

Gastroprotective agent, increasing the prostaglandin production in the gastric mucosa and accelerates ulcer healing

64218-02-6
DCC4188 Plazomicin

Broad spectrum aminoglycoside antibiotic typically used for moderate-to-severe urinary tract infections or pyelonephritis

1154757-24-0
DCC4189 Plc Inhibitor 3017

Novel inhibitor of phospholipase C (PLC) isozyme

DCC4190 pl-dhn

Novel enhancer of Reactive Oxygen Species (ROS), depleting glutathione levels in analogy to piperlongumine but with reduced cell death

1415152-77-0
DCC4191 Plectranthoic Acid

Novel activator of AMPK, inducing apoptotic death in prostate cancer cells

82373-96-4
DCC4192 Plhspt

Plk1 PBD-specific phosphopeptide inhibitor, effectively inhibiting mitotic progression and cell proliferation

DCC4193 Plk1 Pbd-in-143

Novel Inhibitor of the Polo-Box Domain of Polo-like Kinase 1 (Plk1 PBD)

923783-24-8
DCC4194 Plk1-in-7k

Novel polo-like kinase 1 (PLK1) inhibitor

DCC4195 Plx647(ome)

Slightly less potent inhibitor of FMS than PLX647 but has better aqueous solubility

923562-22-5
DCC4196 Pm00104

Potent anticancer tetrahydroisoquinoline alkaloid, being able to form a covalent bond with the amino group of a guanine in selected triplets of DNA duplexes and eventually give rise to double-strand breaks

308359-57-1
DCC4197 Pmed-1

Novel inhibitor of β-catenin signaling, significantly reduced β-catenin activity in hepatoblastoma and several HCC cells

DCC4198 Pmmb-317

Novel potent irriversible dual inhibitor of tubulin and epidermal growth factor receptor (EGFR), inducing the apoptosis of A549 cells in a dose- and time-dependent manner, along with decrease in mitochondrial membrane potential (MMP), production of ROS an

DCC4199 Pmpmease-in L-23

Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway

1190196-76-9
DCC4200 Pmpmease-in L-28

Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway

1190196-77-0
DCC4201 P-mppf Dihydrochloride

Selective 5-HT1A serotonin receptor antagonist

223699-41-0
DCC4202 P-nitro-pifithrin-α

Cell-permeable analog of pifithrin-α, potently blocking p53-mediated expression of p21/WAF1 and apoptosis

389850-21-9
DCC4203 Pnr-4-20

Novel G Protein-Biased Cannabinoid 1 (CB1) Receptor Agonist

DCC4204 Pnu-292137

Potent inhibitor of CDK2/cyclin A

326823-27-2
DCC4205 Pnu-69176e

Allosteric modulator of 5-HT(2C)R with no intrinsic agonist activity

625120-71-0
DCC4206 Pnz-tmp

The first small-molecule approach capable of detecting and controlling engineered cell-cell outputs

DCC4207 Podoverine A

Novel microtubule destabilizing natural product from the Podophyllum species

107882-43-9
DCC4208 Pol I Inhibitor T5

Novel RNA polymerase I inhibitor, targeting ribosomal DNA G-quadruplexes, potently and selectively inhibiting cell growth by high-affinity binding to G4s in ribosomal DNA, impairing RNA polymerase I (Pol I) elongation, inducing a rapid inhibition of Pol I

DCC4209 Pol7001

Novel macrocycle antibiotic with selective and potent activity against P. aeruginosa

944152-19-6
DCC4210 Poloppin-ii

Novel modulator of protein-protein interactions of the mitotic polo-like kinases, targeting KRAS mutant xenografts, indicate avenues, acting synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells

DCC4211 Poloxipan

Pan-Specific Inhibitor of the Polo-Box Domains of Polo-like Kinases Arrests Cancer Cells in Mitosis

1239513-63-3
DCC4212 Poly(ethyleneimine) Solution

Used for the transfection of a broad variety of cell lines; Antimicrobial; Novel binding agent of diffusive gradients in thin-films (DGT) technique (PEI-DGT)

9002-98-6
DCC4213 polygonatone D

Novel activator of Adenosine monophosphate (AMP)-activated protein kinase (AMPK)

1432632-42-2
DCC4214 Polymyxin

Antibiotic as a last-line therapy to treat infections caused by these life-threatening 'superbugs'

1406-11-7
DCC4215 polyphenol 13b

Novel pan-inhibitor of KCa3.1/KCa2 channels

1222380-73-5
DCC4216 Pom2-c-hmbp

Potent Activator of Vγ9Vδ2 T-Lymphocytes; HMBPP ananlog prodrug

DCC4217 Ponfibrate

Hypobetalipoproteinemic and Lipid decreasing agent

53341-49-4
DCC4218 Poziotinib Hydrochloride

Novel pan-human EGF receptor (HER) inhibitor

1429757-68-5
DCC4219 Ppa250

Novel iNOS homodimerization inhibitor

DCC4220 Pparalpha/delta-in-11

The first reported PPARα/δ dual antagonist

DCC4221 Pparalpha/gamma Agonist N15

Novel dual PPARα/γ agonist, ameliorating insulin resistance and gluconeogenesis in vivo and vitro

1821380-90-8
DCC4222 Ppi Inhibitor-i

Novel inhibitor of protein-protein interaction (PPI), blocking #212121; font-family: BlinkMacSystemFont, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 14px; font-style: no

DCC4223 pp-ii-a03

Novel insulin mimetic

1136374-51-0
DCC4224 Ppi-in-3344

Novel pan-RAS-effector PPI inhibitor

DCC4225 Ppk1-in-17

Novel PPK1 inhibitor, preventing UTI effectively through the disruption of the PPK1 function

DCC4226 Ppk1-in-8

Novel PPK1 inhibitor, preventing UTI effectively through the disruption of the PPK1 function

1571-87-5
DCC4227 pppone

Potent and selective antagonist of melanocortin-4 receptor (MC4R)

89011-87-0
DCC4228 Ppq-581

Novel anti-influenza agent, interrupting the crucial RNP trafficking, resulting in influenza replication inhibition, preventing virus-induced cytopathic effects

950381-32-5
DCC4229 Ppt (water-heme Modulator)

Novel Modulator of Water-Heme Interactions in Low-Spin P450 Complexes of CYP2C9d and CYP125A1

1529779-90-5
DCC4230 Ppxy Budding Inhibitor 4

Novel inhibitor of budding of mVP40 and eVP40 VLPs, blocking mVP40-795 Nedd4 protein-protein interaction.

956571-77-0
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