| DC8182 |
Bempedoic Acid(ETC-1002;ESP-55016)
Featured
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ETC-1002(ESP-55016) is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM). |
|
| DC8489 |
ETC-159
Featured
|
ETC-159 is a potent and specific inhibitor of Wnt secretion. ETC-159 inhibits _beta_-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9 nM. |
|
| DC21003 |
ETC-206
Featured
|
ETC-206 (ETC-1907206) is a novel potent, selective MNK1/2 inhibitor with IC50 of 64/86 nM, inhibits eIF4E phosphorylation inhibition in HeLa cell line with IC50 of 321 nM. |
|
| DC8123 |
ETH 157（Sodium ionophore II）
Featured
|
ETH 157（Sodium ionophore II）is a neutral ionophore for liquid-membrane electrodes of high selectivity for Na+. |
|
| DC9016 |
Etamsylate |
Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins. |
|
| DCAPI1235 |
Ethionamide |
Ethionamide |
|
| DC10267 |
Ethosuximide |
Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures. |
|
| DC12182 |
Ethyl docosa-4,7,10,13,16,19-hexaenoate |
Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol. |
|
| DC8821 |
Etifoxine Hydrochloride
Featured
|
Etifoxine Hydrochloride is a psychotropic agent with anxiolytic and anticonvulsant activity. Etifoxine Hydrochloride is an activator of GABAA R β2 and GABAA R β3. |
|
| DC10046 |
Etizolam
Featured
|
Etizolam(AHR3219; Y7131) is a benzodiazepine analog. |
|
| DCAPI1535 |
Etodolac |
Etodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of ab |
|
| DC7411 |
Etofenamate
Featured
|
Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain. |
|
| DC9441 |
Etonogestrel |
Etonogestrel is a steroidal progestin used in hormonal contraceptives.
|
|
| DC2102 |
Etoposide 4'-Phosphate |
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity. |
|
| DC10239 |
Etoricoxib
Featured
|
Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
|
| DC10103 |
ETP-46321
Featured
|
ETP-46321 is a potent and orally bioavailable PI3K α/δ inhibitor with IC50 of 2.3/14.2 nM for p110α/p110β; exhibits potency on mutated p110α(IC50=1.77-2.33 nM, p110a E542K; E545K; H1047R). |
|
| DC7124 |
ETP-46464
Featured
|
ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα, and ATM (IC50= 0.6, 14, 36, 170, and 545 nM, respectively). |
|
| DC10040 |
Etrasimod(APD334)
Featured
|
Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1(S1P1) receptor with an IC50 value of 1.88 nM in CHO cells. |
|
| DC4234 |
Etravirine |
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1). |
|
| DC9884 |
Etretinate |
Etretinate is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. |
|
| DC20376 |
Etriciguat |
Etriciguat is a novel potent, selective, orally available soluble guanylate cyclase (sGC) stimulator.. |
|
| DC8870 |
Eupatilin
Featured
|
Eupatilin is a pharmacologically active flavone derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells. |
|
| DC12061 |
Eurycomanone |
Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. |
|
| DC7125 |
Evacetrapib (LY2484595)
Featured
|
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. |
|
| DC9893 |
Evans Blue |
Evans Blue is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist |
|
| DC9685 |
Evatanepag (CP-533536)
Featured
|
Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM. |
|
| DC1501 |
Everolimus
Featured
|
Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM. |
|
| DC10380 |
Evobrutinib
Featured
|
Evobrutinib is an inhibitor of Bruton's tyrosin kinase (Btk) inhibitor extracted from patent US20140162983 example 0174. |
|
| DC7126 |
QNZ(EVP4593)
Featured
|
EVP4593 is a derivative of 6-aminoquinazoline class that has been previously isolated as an inhibitor of PMA/PHA-induced NF-κB pathway activation in Jurkat cells (IC50= 9 nM). |
|
| DC7987 |
Encenicline hydrochloride (EVP-6124)
Featured
|
Encenicline hydrochloride (EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
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