| DC8414 |
MI-77301 (SAR405838)
Featured
|
MI-77301 (SAR405838) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1. |
|
| DCAPI1514 |
Micafungin sodium
Featured
|
Micafungin(FK463) is an echinocandin antifungal drug, Micafungin inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. |
|
| DC11162 |
MID-1
Featured
|
MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction; increases the IRS-1 protein level in C2C12 myotubes, abrogates MG53-induced IRS-1 ubiquitination and degradation; potent |
|
| DC20962 |
Midazolam |
Midazolam (Dormicum. |
|
| DC23570 |
MIDD0301
Featured
|
MIDD0301 is a potent, positive allosteric, α5β3γ2 selective, GABAA receptor (GABAAR) ligand with EC50 of 17 nM, shows no significant binding at the peripheral GABAAR at 10 uM. |
|
| DC24075 |
Midodrine
Featured
|
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
|
| DC24076 |
Midodrine hydrochloride
Featured
|
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
|
| DC20451 |
MIF-IN-3bb |
MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM. |
|
| DC10328 |
Migalastat hydrochloride
Featured
|
Migalastat hydrochloride (1-Deoxygalactonojirimycin hydrochloride) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. |
|
| DCAPI1324 |
Miglitol (Glyset) |
Miglitol (Glyset) |
|
| DC9545 |
Miglustat (hydrochloride)
Featured
|
Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). |
|
| DC12425 |
MIK665 |
MIK665 (S-64315, MIK-665) is a novel potent, selective Mcl-1 inhibitor with potential pro-apoptotic and antineoplastic activities. |
|
| DCAPI1436 |
Milbemycin oxime
Featured
|
Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~70: 30 ratio). Moxidectin oxime, marketed as Interceptor, is used therapeutically for the prev |
|
| DCAPI1003 |
Milnacipran HCl |
Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively. |
|
| DC3158 |
Milrinone
Featured
|
Milrinone(Primacor) is a a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 μM for the inhibition of FIII PDE |
|
| DC9120 |
Miltefosine
Featured
|
Miltefosine is an alkylphosphocholine drug. |
|
| DC21074 |
Milveterol |
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold). |
|
| DC21075 |
Milveterol hydrochloride |
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold). |
|
| DC21584 |
MIN-101
Featured
|
MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.. |
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|
| DC23395 |
MIND-4 |
MIND-4 is a novel potent, selective, non-competitive SIRT2 deacetylase inhibitor with IC50 of 1.2 uM, Ki of 2.1 uM, and also is an inducer of the NRF2 pathway. |
|
| DC11902 |
Minesapride |
Minesapride (DSP-6952) is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
|
| DC8928 |
Minocycline hydrochloride
Featured
|
Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. |
|
| DC8968 |
Minoxidil |
Minoxidil(U 10858) is an antihypertensive vasodilator medication. |
|
| DC10152 |
Miquelianin (Quercetin 3-O-glucuronide)
Featured
|
Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid. |
|
| DC21919 |
MIR17PTi |
MIR17PTi is a novel LNA gapmeR antisense oligonucleotide (LNA-ASO), first-in-class inhibitor of pri-mir-17-92. |
|
| DC11045 |
miR-21 inhibitor 37 |
miR-21 inhibitor 37 is a novel inhibitor of miR-21 function with EC50 of 5.3 uM in HeLa-miR21-Luc assays, displays no inhibition of miR-122. |
|
| DC21651 |
miR544-IN-1 |
miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis. |
|
| DC3172 |
Mirabegron
Featured
|
Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM. |
|
| DC9275 |
Mirin
Featured
|
Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor that blocks the 3' and 5' exonuclease activity associated with Mre11. |
|
| DCAPI1458 |
Miriplatin |
Miriplatin |
|
