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Z-Asp-CH2-DCB

  Cat. No.:  DC28318   Featured
Chemical Structure
153088-73-4
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Field of application
Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor. Z-Asp-CH2-DCB also inhibits proteases with caspase-like activity. Z-D-CH2-DCB blocks the production of IL-1β, TNF-α, IL-6, and IFN-γ in staphylococcal enterotoxin B (SEB)-stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB-1-stimulated T-cell proliferation in a dose-dependent manner. Z-Asp-CH2-DCB prevents SU5416-induced septal cell apoptosis and emphysema development.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 153088-73-4
Chemical Name: Z-Asp-CH2-DCB
Synonyms: Benzoic acid,2,6-dichloro-, (3S)-4-carboxy-2-oxo-3-[[(phenylmethoxy)carbonyl]amino]butylester;"Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE";Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE;Z-Asp-2006-dichlorobenzoyloxymethylketone;Z-Asp-CH2-DCB;ICE INHIBITOR V;ICE INHIBITOR VI;PASE-1 INHIBITOR III;PASE-1 INHIBITOR V;Z-D-CH2-DCB;Z-VAL-ALA-ASP(OME)-FLUOROMETHYLKETONE;CASPASE-1 INHIBITOR V;Z-Asp-[(2,6-dichlorobenzoyl)oxy]methane;CASPASE-1 INHIBITOR III;Z-L-ASP-ALPHA-[(2,6-DICHLOROBENZOYL)OXY]METHANE;HY-113953;CS-0064759;(S)-3-(((benzyloxy)carbonyl)amino)-5-((2,6-dichlorobenzoyl)oxy)-4-oxopentanoic acid;MS-28260;(3S)-5-(2,6-dichlorobenzoyl)oxy-4-oxo-3-(phenylmethoxycarbonylamino)pentanoic acid;Z-Asp-DCB;SCHEMBL3686640;153088-73-4;AKOS040740597;MFCD00674885;Z-Asp-2,6-dichlorobenzoyloxymethylketone;CHEMBL108574;Caspase-1 Inhibitor V;carbobenzoxy-l-aspart-1-yl-[(2,6-dichlorobenzoyl)oxy]methane;Z-ASP-CH2-DCB;Z-ASP-[(2,6-DICHLOROBENZOYL)OXY]METHANE;N-CBZ-L-ASPARTIC ACID A-(2 6-DICHLORO- &
SMILES: O=C(O)C[C@@H](C(COC(C1=C(Cl)C=CC=C1Cl)=O)=O)NC(OCC2=CC=CC=C2)=O
Formula: C20H17NO7Cl2
M.Wt: 454.25748
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_12371_DC28318_153088-73-4
COA
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Cat. No. Product name Field of application
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