| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC12335 | 5'-GTP trisodium salt hydrate (Guanosine 5'-triphosphate trisodium salt hydrate) | 5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. |
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| DC7494 | SB-242084 HCl | 5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2Breceptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity. |
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| DC5179 | 5-IODOTUBERCIDIN | 5-Iodotubercidin (Itu) has been shown to inhibit mitogen-activated protein kinase (ERK2) (Ki = 525 nM), adenosine kinase (ADK) (Ki = 30 nM), casein kinases 1 & 2 (CSNK1A1 & CSNK2A1), protein kinase A (PKA) and insulin receptor kinase (IC50 ranging from 0. |
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| DC20150 | 5-Methoxyflavone | 5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors. |
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| DC10990 | 5MPN | 5MPN a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3. |
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| DC23335 | 5-NIdR | 5-NIdR (5-nitro-indolyl-2'-deoxynucleoside) is a non-natural nucleotide produces cytostatic and cytotoxic effects against human leukemia cells by altering cell-cycle progression. |
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| DC23334 | 5-NITP | 5-NITP (5-nitro-indolyl-2'-deoxyribose triphosphate) is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.. |
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| DC9444 | 5-R-Rivaroxaban | 5-R-Rivaroxaban is (R) enantiomer of Rivaroxaban. |
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| DC7604 | FAI (5S rRNA modificator) | 5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification. |
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| DC10187 | 666-15 | 666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM. |
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| DC20195 | 6-(Dimethylamino)purine；N,N-Dimethyladenine | 6-Dimethylaminopurine is a serine threonine protein kinase inhibitor. It inhibits the germinal vesicle breakdown and the meiotic maturation of oocytes. |
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| DC23336 | 6-Ethylthioinosine | 6-Ethylthioinosine (6-ETI. |
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| DC20604 | 6-FABA | 6-FABA (6-Fluoroanthranilic Acid) is a small-molecule inhibitor of MTB tryptophan synthesis that converts Mtb into a tryptophan auxotroph and restores the efficacy of a failed host defense. |
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| DC9372 | 6-FAM SE | 6-FAM SE is another isomer of carboxyfluorescein. |
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| DC9376 | 6-FITC | 6-Fluorescein isothiocyanate(6-FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. |
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| DC7736 | 6H05 | 6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C). |
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| DC12326 | 6-Hydroxybentazon (6-Hydroxybentazone) | 6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides. |
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| DC20297 | 6-Hydroxy-DL-DOPA | 6-Hydroxy-DL-DOPA is a small-molecule that disrupts with RAD52 oligomerization, inhibits ssDNA binding by RAD52 with IC50 of 1.1 uM and by RAD52 (1 209) with IC50 of 1.6 uM. |
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| DC8864 | 6-Mercaptopurine (6-MP) Monohydrate | 6-Mercaptopurine Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. |
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| DC10854 | 6-MITC | 6-MITC is an inhibitor of viability of both PANC-1 and BxPC-3 cells. It also acts as an inhibitor of the expression of CSC signaling molecule SOX2. |
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| DC12540 | 6-MOMIPP | 6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro. |
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| DC7925 | GTPL-5846 (6-OAU) | 6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay. |
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| DC8953 | 6-TG/Thioguanine | 6-Thioguanine(6-TG) belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites; it is a purine analogue of the nucleobase guanine. |
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| DC10215 | 7,8-Dihydroxyflavone | 7,8-Dihydroxyflavone acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF). |
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| DC7876 | 7ACC2 | 7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells. |
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| DCAPI1394 | 7-Aminocephalosporanic acid | 7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates. |
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| DC12463 | 7-BIA | 7-BIA is a small molecule 7-butoxy illudalic acid analog that targets receptor-type protein tyrosine phosphatase D (PTPRD, IC50=1-3 uM) with some specificity. |
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| DC12215 | 7-Dehydrocholesterol | 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3. |
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| DC21513 | 7DG | 7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR. |
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| DC10855 | 7-Epi 10-Desacetyl Paclitaxel | 7-Epi 10-Desacetyl Paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells. |
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