| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10856 | 7-Epipaclitaxel Featured | 7-epi-Taxol is a paclitaxel binds to tubulin, interfering with the normal function of microtubule. |
|
| DC8388 | 8-Bromo-cAMP Featured | 8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator. |
|
| DC26033 | 8-Hydroxy-efavirenz Featured | 8-Hydroxy-efavirenz is the primary metabolite of the antiretroviral drug Efavirenz, stimulates the glycolytic flux in cultured rat astrocytes. |
|
| DC10186 | 8-O-Acetyl shanzhiside methyl ester | 8-O-Acetyl shanzhiside methyl ester (ND01) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. |
|
| DC10537 | 8-OH-DPAT Featured | 8-OH-DPAT is a research chemical of the aminotetralin chemical class and has been widely used to study the function of the 5-HT1A receptor. |
|
| DC11964 | Lys01 | A 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ).. |
|
| DC20669 | Imexon | A 2-cyanoaziridine derivative with antitumor activity in some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma. |
|
| DC23303 | A 385358 | A 385358 is a potent, selective, cell-permeable Bcl-XL inhibitor with Ki of 0.8 nM, displays >80-fold selectivity over Bcl-2 (Ki=64 nM). |
|
| DC24006 | Nucleoside-Analog-2 | A 4′-azidocytidine analogue that shows anti-HCV activity.. |
|
| DC24009 | Nucleoside-Analog-1 | A 4′-azidocytidine analogue that shows anti-HCV activity.. |
|
| DC9628 | A 419259 (trihydrochloride) Featured | A 419259 3Hcl is an apoptosis inducing agent that inhibits Src family kinases (c-Src). |
|
| DC8020 | A77-01 Featured | A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM. |
|
| DC7038 | A 922500 Featured | A 922500 is a potent, selective, and orally bioavailable DGAT-1 inhibitor with IC50 values of 7 nM and 24 nM for human and mouse DGAT-1 respectively. |
|
| DC22355 | Lisinopril | A angiotensin-converting enzyme (ACE) inhibitor for treatment of hypertension, heart failure, and after heart attacks.. |
|
| DC22846 | NSC-34931 | A anti-HIV-1 compound that interferes with HIV-I integrase binding to viral DNA.. |
|
| DC22455 | Ro5-3335 | A benzodiazepine inhibitor that directly interacts with RUNX1 and CBFβ, represses RUNX1/CBFβ-dependent transactivation in reporter assays. |
|
| DC11768 | TAM-16 | A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13). |
|
| DC22605 | Benzophenonetetracarboxylic acid | A benzophenone tetracarboxylic derivative that can improve the activity and stability of alkaline phosphatases from psychrophilic and mesophilic organisms.. |
|
| DC20526 | r(GGGGCC)n binder 1a | A bioactive, specific small molecule that targets RNA of the expanded repeat (r(GGGGCC)exp) with Kd of 9.7 uM. |
|
| DC25030 | Migrastatin | A biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration. |
|
| DC21819 | WP760 | A bis-anthracycline and melanoma selective agent that demonstrates anti-melanoma activity at low nanomolar concentrations. |
|
| DC22873 | TM2 115 Featured | A BIX-01294 derivative that inhibit malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death. |
|
| DC7537 | B-Raf inhibitor (BenzaMide) | A B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases. |
|
| DC24040 | AKT inhibitor | A broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM(biochemical assay), and 0.31 nM (cell function assay). |
|
| DC23922 | Cercosporamide Featured | A broad-spectrum natural antifungal compound that acts as a selective and highly potent fungal Pkc1 kinase inhibitor. |
|
| DC23987 | SU14813 maleate | A broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS. |
|
| DC23920 | GGTI298 | A CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
|
| DC22519 | Norverapamil hydrochloride Featured | Norverapamil HCl is a calcium channel blocker. It is the main active metabolite of verapamil. |
|
| DC24165 | Aldicarb sulfone | A carbamate insecticide that acts as a fast-acting cholinesterase inhibitor.. |
|
| DC24166 | Aldicarb | A carbamate insecticide that acts as a fast-acting cholinesterase inhibitor.. |
|
