| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22345 | Penthiopyrad Featured | A carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps. |
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| DC22369 | Flumorph | A carboxylic acid amide (CAA) fungicide.. |
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| DC22678 | Acebutolol | A cardioselective beta blocker for the treatment of hypertension and arrhythmias.. |
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| DC22489 | Acebutolol hydrochloride Featured | Acebutolol HCl is a cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action. |
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| DC22875 | Hexamethylene bisacetamide | A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade. |
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| DC11652 | Ischemin sodium | A cell permeable CBP bromodomain inhibitor with Kd of 19 uM. |
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| DC11653 | Ischemin | A cell permeable CBP bromodomain inhibitor with Kd of 19 uM. |
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| DC11648 | 2-D08 Featured | A cell permeable, mechanistically unique inhibitor of protein sumoylation. |
|
| DC20340 | Chromeceptin Featured | A cell-permeable benzochromene that selectively impairs the viability and growth of IGF2-overexpressing hepatocellular carcinoma cells, binds to MFP-2, stimulates the expression of IGFBP-1 and SOCS-3 through activation of STAT6. |
|
| DC20471 | Naphthol AS-E | A cell-permeable inhibitor of the KIX-KID interaction and CREB-mediated gene transcription (IC50=2.26 uM). |
|
| DC21591 | Ru360 | A cell-permeable mitochondrial calcium uptake inhibitor that binds to mitochondria with high affinity (Kd=340 pM) and blocks Ca2+ uptake into mitochondria in vitro with IC50 of 184 pM. |
|
| DC22594 | D-JNKI-1 | A cell-permeable peptide inhibitor of JNK kinase. |
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| DC22590 | Fumarase-IN-1 | A cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle). |
|
| DC23206 | Bax inhibitor peptide V5 Featured | A cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. |
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| DC20421 | IQDMA | A cell-permeable, small molecule inhibitor of the transcription factor STAT5 that exhibits anticancer activity and inhibits the growth of A549, HL-60 and K562 cells with IC50 of 8, 5 and 8 uM, respectively.. |
|
| DC22378 | DPH Featured | A cell-permeable, small-molecule c-Abl kinase activator with pEC50 of 6.1(EC50=794 nM). |
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| DC24193 | BAPTA Featured | BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. |
|
| DC22363 | 6-O-α-Maltosyl-β-cyclodextrin | A cellular cholesterol modifier that can form soluble inclusion complex with cholesterol. |
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| DC20493 | PDMP hydrochloride | A ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest. . |
|
| DC23222 | Cinepazide | A cerebral vasodilator that acts as a calcium blocker. |
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| DC22502 | Ibrutinib-biotin | A chemical probe that consists of Ibrutinib linked to biotin via a long chain linker, has IC50 of 0.755-1.02 nM for Btk kinase. |
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| DC22344 | Novaluron Featured | A chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators.. |
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| DC22729 | Flecainide | A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart, slowing the upstroke of the cardiac action potential. |
|
| DC24086 | Azimilide Featured | Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. |
|
| DC11873 | CDK12 inhibitor E9 R-isomer | A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux. |
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| DC11874 | CDK12 inhibitor E9 racemate | A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux. |
|
| DC6912 | Ethofibrate Featured | A combination of clofibrate and niacin, used to treat hyperlipidaemias |
|
| DC23696 | CGH2466 | A combined adenosine receptor antagonist, p38 MAPK and PDE4 inhibitor, inhibits A1, A2b and A3 receptor (IC50=19, 21 and 80 nM), p38α, p38β and PDE4D (IC50=87, 400 and 22 nM). |
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| DC23234 | Atorvastatin | A competitive inhibitor of HMG-CoA reductase that acts as a lipid-lowering agent for prevention of events associated with cardiovascular disease.. |
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| DC22904 | VPC 23019 Featured | A competitive S1P receptor antagonist with pKi of 7.86 and 5.93 for S1P1 and S1P3, respectively, in radioligand binding assay. |
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