DC22515 |
Trans-ACPD
Featured
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trans-ACPD is a selective agonist for metabotropic glutamate receptors, acting at both group I and group II mGlu receptors. |
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DC24194 |
Tripelennamine hydrochloride |
A first-generation antihistamine that acts primarily as H1 receptor antagonist. |
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DC20738 |
Livoletide
Featured
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A first-in-class analogue of unacylated ghrelin, and unacylated ghrelin receptor agonist. |
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DC12001 |
AG311 |
A first-in-class antitumor and antimetastatic agent that induces necrosis in breast cancer tumors, inhibits inhibit mitochondria complex I activity and reduces HIF-1α stabilization. |
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DC11813 |
CM-414 |
A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM). |
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DC11815 |
trans CM-414 |
A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM). |
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DC11814 |
cis CM-414 |
A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM). |
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DC11707 |
MDVN-1003 |
A first-in-class, selective, orally bioavailable, dual inhibitor of BTK and PI3Kδ kinases with IC50 of 32.3 nM and 16.9 nM, respectively. |
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DC11531 |
Teslexivir |
A first-in-class, small molecule protein-protein inhibitor of the interaction between the E1 and E2 proteins of HPV types 6 and 11. |
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DC22520 |
Porcine dynorphin A(1-13) |
A form of dynorphin and an endogenous opioid peptide with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys.. |
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DC22352 |
Gatifloxacin hydrochloride |
A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |
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DC22351 |
Gatifloxacin mesylate |
A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |
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DC22353 |
Gatifloxacin |
A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |
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DC24178 |
Moxifloxacin
Featured
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A fourth-generation synthetic fluoroquinolone, broad-spectrum antibacterial agent that is active against both Gram-positive and Gram-negative bacteria. |
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DC11489 |
6-alkynyl Fucose |
A fucose analog that inhibits Dll-induced Notch signaling by reducing Notch ligand Dll1-Notch1 binding, but not Jag1. |
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DC23737 |
Azaphilone-9 |
A fungal natural product that binds to HuR and inhibits HuR-RNA interaction in vitro with IC50 of 1.2 uM. |
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DC24161 |
Acamprosate calcium |
A GABA receptor agonist and modulator of glutamatergic systems. |
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DC21669 |
SNAP 5114 |
A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively. |
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DC20497 |
PGRMC2-IN-25 |
A gain-of-function ligand for PGRMC2 (progesterone receptor membrane component 2) to promote adipogenesis. |
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DC21363 |
Lucerastat |
A galactose analogue that is an UDP-glucose ceramide glucosyltransferase (UGCG/GCS) inhibitor (IC50=41.4 uM). |
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DC22490 |
3-Bromopyruvic acid
Featured
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A glycolytic inhibitor that inhibits hexokinase II activity, suppresses ATP production, and induces endoplasmic reticulum (ER) stress. |
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DC21844 |
Carbenoxolone |
A glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.. |
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DC21845 |
Carbenoxolone disodium |
A glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.. |
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DC22527 |
Cyclic somatostatin
Featured
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A growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. |
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DC22347 |
Penciclovir
Featured
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A guanosine analogue antiviral agent used for the treatment of various herpesvirus (HSV) infections. |
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DC22358 |
Valproic acid sodium salt |
A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
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DC22359 |
Valproic acid |
A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
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DC23983 |
Pyraclonil |
A herbicide agent. . |
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DC24171 |
Furilazole |
A herbicide safener for gramineous crops.. |
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DC22635 |
SPDP
Featured
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SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker u |
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