| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC26102 | TK05 | A potent and selective inhibitors of leukotriene C4 synthase (LTC4S) with IC50 of 95 nM, Ki of 6 nM. |
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| DC24066 | CYT387 mesylate Featured | A potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM. |
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| DC24067 | CYT387 sulfate salt Featured | A potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM. |
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| DC22707 | Ibodutant | A potent and selective linear tachykinin NK2 receptor antagonist with pKb of 9.3. |
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| DC23410 | BI 186908 | A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM. |
|
| DC22887 | THIQ | A potent and selective melanocortin 4 receptor (MC4R) agonist with EC50 of 2.1 nM. |
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| DC23966 | mTOR-IN-1 | A potent and selective mTOR inhibitor with Ki of 1.5 nM. |
|
| DC20474 | Nek2 inhibitor (R)-21 | A potent and selective NIMA-related Kinase 2 (NEK2) inhibitor with IC50 of 22 nM, >200-fold selectivity over Plk1, Mps1, Aurora A and CDK2. |
|
| DC22671 | Saredutant | A potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor. |
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| DC22970 | BMS 843496 | A potent and selective PDE10A inhibitor with binding affinity (Kd) of 0.15 nM, IC50 of 2.11 nM. |
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| DC22968 | TC-E 5005 | A potent and selective PDE10A inhibitor with IC50 of 7.28 nM. |
|
| DC26074 | CD 1530 | A potent and selective RARγ receptor agonist with Ki of 150 nM. |
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| DC22341 | H-1152 | A potent and selective ROCK inhibitor with Ki of 1.6 nM. |
|
| DC22655 | UNC-1679 Featured | UNC-1679 (UNC1679) is a potent and selective small molecule chemical probe of a methyl-lysine reader protein L3MBTL3 with Ki of 0.35 uM. |
|
| DC24175 | A-770041 | A potent and selective small-molecule inhibitor of Lck with IC50 of 147 nM. |
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| DC21581 | RO 5203648 Featured | A potent and selective TAAR1 partial agonist with Ki of 0.5, 1.0, 6.8 and 2.6 nM for mouse, rat, human and monkey TAAR1, respectively. |
|
| DC22715 | RP-67580 | A potent and selective tachykinin NK1 receptor antagonist with Ki of 2.9 nM. |
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| DC23840 | IN-1233 | A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.. |
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| DC23839 | IN-1233 phosphate | A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.. |
|
| DC22380 | NNC 55-0396 2HCl Featured | NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. IC50 value: 6.8 nMTarget: Cav3.1 T-type channelNNC 55-0396 can be an essential tool in preventing human ovarian cancer cell proliferation as a result of its ability to inhibit the function of T-type Ca2+ channels. It is believed that NNC 55-0396 may functions by dissolving in or passing through the plasma membrane of cells. |
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| DC22534 | PI4KIIIbeta-IN-10 Featured | A potent and selective type III phosphatidylinositol 4-kinase (PI4KIIIβ) inhibitor with IC50 of 3.6 nM. |
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| DC23086 | Vandetanib hydrochloride | A potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
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| DC25087 | Vandetanib trifluoroacetate | A potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
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| DC11984 | AMG 8379 | A potent and selective voltage-gated sodium channel Nav1.7 antaognist with IC50 of 8.5 nM. |
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| DC20627 | ABT 089 dihydrochloride | A potent and selective α4β2 nAChR agonist with Ki of 16 nM. |
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| DC22885 | TAN-67 dihydrobromide | A potent and selective δ-opioid receptor agonist that has high affinity and selectivity for the δ1 subtype with Ki of 1.12 nM. |
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| DC11670 | MK-4409 | A potent and selective, brain penetrant FAAH inhibitor with IC50 of 11 nM. |
|
| DC23520 | VU 6001966 | A potent and selective, CNS penetrant mGlu2 negative allosteric modulator with IC50 of 78 nM. |
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| DC23521 | VU 6010572 | A potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM. |
|
| DC22979 | PF-04822163 | A potent and selective, CNS-penetrant PDE1 inhibitor with IC50 of 2.4 nM for PDE1B.. |
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