Cycloastragenol

Cas No.:	84605-18-5
Chemical Name:	Cyclogalegigenin
Synonyms:	Cycloastragenol;(3b,6a,16b,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;Cyclogalagenin;Cyclogalegenin;Cyclogalegigenin;Cyclogalgeginin;(3b,5ξ,6a,9ξ,10ξ,16b,17ξ,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;(3beta,6alpha,16beta,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;(3beta,5xi,6alpha,9xi,10xi,16beta,17xi,24R)-20,24-epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;3-O-ferulylcycloartenol;Cycloartenol ferulic acid ester;cycloartenol trans-ferulate;cycloartenyl ferulate;Oryzanol A;Ring astragalus alcohol;Astramembrangenin;X37D9F2L0V;Cycloastragenol, >=98% (HPLC);Cyclogalegenol;Cyclosiversigenin;WENNXORDXYGDTP-UOUCMYEWSA-;s4981;C3469;Q3979404;InChI=1/C30H50
SMILES:	O([H])[C@@]1([H])C([H])([H])[C@@]2([H])[C@]3(C([H])([H])[H])C([H])([H])[C@@]([H])([C@]([H])([C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C(C([H])([H])[H])(C([H])([H])[H])O[H])O4)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]32C([H])([H])[C@]23C([H])([H])C([H])([H])[C@@]([H])(C(C([H])([H])[H])(C([H])([H])[H])[C@@]21[H])O[H])O[H]
Formula:	C30H50O5
M.Wt:	490.7150
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Cycloastragenol, a natural tetracyclic triterpenoid, was first identified when screening Astragalus membranaceus extracts for active ingredients with antiaging properties.

References:

[1]. Jing Zhu, et al. In vitro Intestinal Absorption and First-pass Intestinal and Hepatic Metabolism of Cycloastragenol, a Potent Small Molecule Telomerase Activator. Drug Metabolism and Pharmacokinetics Volume 25, Issue 5, 2010, Pages 477-486 [2]. WEI Bao-hong, et al. Effect of continuous oral cycloastragenol on the activity of cytochrome P450 enzymes in rats. Chinese New Drugs Journal, 2014 -04 [3]. Ip FC, et al. Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management. Neurosignals. 2014;22(1):52-63.