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| Cas No.: | 1037798-41-6 |
| Chemical Name: | 1H-1,2,4-Triazole-3,5-diamine, N3-[4-[4-(1R,2R,4S)-bicyclo[2.2.1]hept-2-yl-1-piperazinyl]phenyl]-1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)- |
| Synonyms: | R 916562;R-916562;R562 |
| SMILES: | N(C1N=C(Cl)N=C2C(C)=CSC2=1)1C(N)=NC(NC2=CC=C(N3CCN([C@H]4CC5CC4CC5)CC3)C=C2)=N1 |
| Formula: | C26H30ClN9S |
| M.Wt: | 536.099 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | R916562 (R562) is a potent, dual Axl/VEGF-R2 inhibitor with celluar IC50 of 136 nM for Axl; blocks growth of MDA-MB-231 breast carcinomas implanted subcutaneously in nu/nu mice, also shows efficacy in the Caki-1 human renal carcinoma xenograft model. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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