UAMC00039|UAMC-00039|DPP-II inhibitor

Cas No.:	697797-51-6
Chemical Name:	(2S)-2-Amino-4-[[(4-chlorophenyl)methyl]amino]-1-(1-piperidinyl)-1-butanone dihydrochloride
Synonyms:	UAMC 00039,UAMC-00039
SMILES:	ClC1=CC=C(CNCC[C@H](N)C(N2CCCCC2)=O)C=C1.Cl.Cl
Formula:	C₁₆H₂₄ClN₃O^.₂HCl
M.Wt:	382.76
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

UAMC00039 dihydrochloride is a potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC50 = 0.48 nM). UAMC00039 exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC50 values are 78.6, 142 and 165 μM, respectively). Orally available.

MSDS

COA

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2018-0101

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