BI-4924
Cat. No.: DC70252
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Chemical Structure
2244452-09-1
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Field of application
BI-4924 (BI 4924) is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.BI-4924 splays high selectivity against the majority of other dehydrogenase targets.
Cas No.: |
2244452-09-1 |
Chemical Name: |
2244452-09-1 (Free acid) |
Synonyms: |
2-[4-[(1~{S})-1-[[4,5-bis(chloranyl)-1,6-dimethyl-indol-2-yl]carbonylamino]-2-oxidanyl-ethyl]phenyl]sulfonylethanoic acid;2-{4-[(1S)-1-[(4,5-Dichloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2-hydroxyethyl]benzenesulfonyl}acetic acid;K5K;2244452-09-1 (Free acid);BI-4924 |
SMILES: |
ClC1=C(C(C([H])([H])[H])=C([H])C2=C1C([H])=C(C(N([H])[C@]([H])(C([H])([H])O[H])C1C([H])=C([H])C(=C([H])C=1[H])S(C([H])([H])C(=O)O[H])(=O)=O)=O)N2C([H])([H])[H])Cl |
Formula: |
C21H20Cl2N2O6S |
M.Wt: |
499.3643 |
Purity: |
98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
MSDS
COA
LOT NO. |
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2018-0101 |
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