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BPA-B9

Cat. No.: DC73855 Featured

Chemical Structure

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Field of application

BPA-B9 (Bipyridine amide B9) is a small molecule RXRα-targeted anti-mitotic agent, binds to RXRα (Kd=39 nM) and selectively inhibits the p-RXRα/PLK1 interaction to induce mitotic arrest and catastrophe in cancer cells.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:
Chemical Name:	BPA-B9
SMILES:	O=C(NC1=NC=CC(C2=CC(N3CCC(CO)CC3)=NC=C2)=C1)/C=C/C4=CC=CC=C4
Formula:	C₂₅H₂₆N₄O₂
M.Wt:	414.51
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC73855	BPA-B9	BPA-B9 (Bipyridine amide B9) is a small molecule RXRα-targeted anti-mitotic agent, binds to RXRα (Kd=39 nM) and selectively inhibits the p-RXRα/PLK1 interaction to induce mitotic arrest and catastrophe in cancer cells.
DC40237	Bigelovin	Bigelovin, a sesquiterpene lactone isolated from Inula helianthus-aquatica, is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.

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