BPKDi

  Cat. No.:  DC71294   Featured
Chemical Structure
1201673-28-0
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More than 5000 active chemicals with high quality for research!
Field of application
BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes.
Cas No.: 1201673-28-0
Chemical Name: Bpkdi
Synonyms: bpkdi;bipyridyl PKD inhibitor;GTPL9370;BDBM50324323;6-Piperazino-2'-(cyclohexylamino)-2,4'-bipyridine-4-carboxamide;2'-(Cyclohexylamino)-6-(1-piperazinyl)-[2,4'-bipyridine]-4-carboxamide;2'-(Cyclohexylamino)-6-(piperazin-1-yl)-2,4'-bipyridine-4-carboxamide;2-[2-(cyclohexylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide;2''-Cyclohexylamino-6-piperazin-1-yl[2,4'']bipyridinyl-4-carboxylicAcid Amide
SMILES: O=C(C1C=C(C2C=CN=C(C=2)NC2CCCCC2)N=C(C=1)N1CCNCC1)N
Formula: C21H28N6O
M.Wt: 380.486623764038
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_35529_DC71294_1201673-28-0
COA
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Cat. No. Product name Field of application
DC71294 BPKDi BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes.
DC7385 CID-755673 CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM; exhibits selective PKD1 inhibition when compared with AKT, PLK1, CAK, CAMKIIα, and PKC isoforms.
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