CAY10698

  Cat. No.:  DC46158   Featured
Chemical Structure
684236-01-9
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Field of application
CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2.
Cas No.: 684236-01-9
Chemical Name: 4-((2-hydroxy-3-methoxybenzyl)amino)-N-(thiazol-2-yl)benzenesulfonamide
Synonyms: 4-((2-hydroxy-3-methoxybenzyl)amino)-N-(thiazol-2-yl)benzenesulfonamide
SMILES: COC1C=CC=C(CNC2=CC=C(S(NC3=NC=CS3)(=O)=O)C=C2)C=1O
Formula: C17H17N3O4S2
M.Wt: 391.464581251144
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2[1].
References: [1]. David J. Maloney, et al. 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC46158 CAY10698 CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2.
DC44939 CDC 5-LO inhibitor Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent and direct inhibitor of 5-LO (5-Lipoxygenase) that reduces 5-LO activity in cell-free assays. CDC also inhibits 12-LO and 15-LO.
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