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IM-250

Cat. No.: DC70505 Featured

Chemical Structure

2305750-23-4

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Field of application

IM-250 is a potent HSV-1 helicase primase inhibitor, inhibits HSV-1 replication with IC50 of 20 nM (clinical isolate of HSV-1).IM-250 dispalys similar IC50 values (20-30 nM) against ACV-resistant HSV-1 clinical isolates 2 and 3 and ACV-resistant HSV-2 clinical isolates 7 and 8.IM-250 exhibits a broad therapeutic window against HSV-1 in vitro with pronounced higher SI values as obtained for acyclovir (ACV).IM-250 shows in vivo efficacy and attenuates viral burden in HSV-1 infection mouse model.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	2305750-23-4
Chemical Name:	IM-250
Synonyms:	IM-250
SMILES:	N(C1=NC(C)=C(S(=O)(=N)C)S1)(C)C(=O)CC1C=CC(C2C=C(F)C=CC=2F)=CC=1
Formula:	C₂₀H₁₉F₂N₃O₂S₂
M.Wt:	435.510568857193
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC70505	IM-250	IM-250 is a potent HSV-1 helicase primase inhibitor, inhibits HSV-1 replication with IC50 of 20 nM (clinical isolate of HSV-1).IM-250 dispalys similar IC50 values (20-30 nM) against ACV-resistant HSV-1 clinical isolates 2 and 3 and ACV-resistant HSV-2 clinical isolates 7 and 8.IM-250 exhibits a broad therapeutic window against HSV-1 in vitro with pronounced higher SI values as obtained for acyclovir (ACV).IM-250 shows in vivo efficacy and attenuates viral burden in HSV-1 infection mouse model.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.