Cat. No. | Product name | CAS No. |
DC23024 |
NSC 65828
Featured
NSC 65828 (NCI65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM. |
501444-06-0 |
DC21683 |
NSC 663284
Featured
NSC 663284 (SPS8I1;DA3003-1) is a potent inhibitor of the dual specificity protein phosphatase Cdc25 with Ki of 9/95//89 nM for Cdc25A/Cdc25B2/Cdc25C, displays 20- and 450-fold more selective over VHR or PTP1B phosphatases. |
383907-43-5 |
DC10697 |
NSC 80538
Featured
NSC 80538 is a bioactive compound. |
370-26-3 |
DC22794 |
NSC112200
Featured
NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2, promotes proteasomal degradation of EZH2 and inhibits the viability of TNBC cells. |
28293-38-1 |
DC9872 |
NSC15364
Featured
NSC15364 is an inhibitor of Shiga Toxin. |
4550-72-5 |
DC12657 |
NSC228155
Featured
NSC228155 is an activator of EGFR. It binds to the sEGFR dimerization domain II and modulates EGFR tyrosine phosphorylation. |
113104-25-9 |
DC9989 |
NSC23005 free acid
Featured
NSC23005 is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models. |
6314-70-1 |
DC9988 |
NSC23005 sodium
Featured
NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models. |
1796596-46-7 |
DC11269 |
MSX-127(NSC23026)
Featured
NSC-23026, also known as MSX-127, is a CXCR4 receptor modulator. |
6616-56-4 |
DC12478 |
NSC 260594
Featured
NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ). |
906718-66-9 |
DC9641 |
NSC348884
Featured
NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication. |
81624-55-7 |
DC9672 |
NSC5844 (RE640)
Featured
NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties. |
140926-75-6 |
DC9257 |
NSC59984
Featured
NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway.The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 μM for p53-null HCT116 cells. |
803647-40-7 |
DC20228 |
NSC617145(WRN inhibitor)
Featured
NSC617145 is a Werner syndrome helicase (WRN) helicase inhibitor (IC50 = 250 nM). |
203115-63-3 |
DC10001 |
NSC632839
Featured
NSC632839 is a nonselective isopeptidase inhibitor, which inhibits USP2, USP7, and SENP2 with EC50s of 45±4 μM, 37±1 μM, and 9.8±1.8 μM, respectively. |
157654-67-6 |
DC5145 |
NSC697923
Featured
NSC697923 is a selective inhibitor of Ubc13-Uev1A |
343351-67-7 |
DC10484 |
NSC781406
Featured
NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα. |
1676893-24-5 |
DC7165 |
NSI-189
Featured
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine. |
1270138-40-3 |
DC9754 |
NT-157
Featured
NT157 is a selective inhibitor of IRS-1/2, IC50 values at sub-micromolar doses (ranging from 0.3 to 0.8 μM) . |
1384426-12-3 |
DC7935 |
NU1025
Featured
NU 1025 is an inhibitor of poly(ADP-ribose) polymerases (PARP) (IC50 = 400 nM). |
90417-38-2 |
DC8214 |
NU6027
Featured
NU 6027 inhibits both CDK1 and CDK2 with IC50 values of 2.9 and 2.2 µM, respectively. |
220036-08-8 |
DC10734 |
NU2058
Featured
NU2058 is a guanine-based CDK inhibitor with IC50 of 17 μM and 26 μM for CDK2 and CDK1. |
161058-83-9 |