Cat. No. | Product name | CAS No. |
DC8463 |
NVP-TNKS656
Featured
NVP-TNKS656(TNKS-656) is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2. |
1419949-20-4 |
DC12583 |
NVR 3-778
Featured
NVR 3-778 (NVR3-778, NVR 3778) is a small molecule inhibitor of HBV replication that targets the viral core protein, a first-in-class capsid assembly modulator. |
1445790-55-5 |
DC10473 |
NVS-PAK1-1
Featured
NVS-PAK1-1 potently inhibits autophosphorylation of PAK1 (S144) at 0.25 µM in the Su86.86 cell line and MEK S289 phosphorylation with an IC50 = 0.21 in Su86.86 cells in which PAK2 is downregulated. |
1783816-74-9 |
DC11382 |
NYX-2925
Featured
NYX-2925 is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory. |
2012536-16-0 |
DC10807 |
O304
Featured
O304 is a novel AMPK activator. |
1261289-04-6 |
DC8346 |
O4I-1
Featured
O4I1-1 is a Oct3/4 inducer. Increases Oct3/4 mRNA levels in HEK293 cells by 2.5- and 4-fold at 10 μM and 20 μM, respectively. |
175135-47-4 |
DC8345 |
O4I2
Featured
O4I2 is a a new class of small molecules suitable for iPSC generation, showed high activity in enforcing Oct3/4 expression. |
165682-93-9 |
DC8208 |
OAC1
Featured
OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process. |
300586-90-7 |
DC8273 |
OAC2
Featured
OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts; an analog of OAC1. |
6019-39-2 |
DC21437 |
OAT-2068
Featured
OAT-2068 is a potent, selective, orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1) with IC50 of 29 nM, 143-fold selectivity over mAMCase. |
2221950-65-6 |
DC7217 |
Obatoclax (GX15-070)
Featured
Obatoclax (GX15-070) is Bcl-2 homology domain-3 (BH3) mimetic, antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L). |
803712-67-6 |
DC10134 |
Obicetrapib (AMG-899,TA-8995)
Featured
Obicetrapib is a CETP inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy. |
866399-87-3 |
DC1026 |
OC000459(Timapiprant)
Featured
OC000459, a Potent, Selective, and Orally Active D Prostanoid Receptor 2 Antagonist. |
851723-84-7 |
DC10144 |
Ochratoxin A(OTA)
Featured
Ochratoxin A demonstrates nephrotoxicity and teratogenesis in animals, and shows inhibition of bacterial, yeast, and liver FARSL (phenylalanyl-tRNA synthetases) competitive with phenylalanine. |
303-47-9 |
DC10145 |
Ochratoxin B(OTB)
Featured
Ochratoxin B(OTB) is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion. |
4825-86-9 |
DC5040 |
Oclacitinib maleate
Featured
Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. |
1640292-55-2 |
DC12298 |
Octreotide acetate (SMS 201-995 (acetate))
Featured
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently. |
79517-01-4 |
DC6401 |
Odanacatib (MK 0822)
Featured
Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively. |
603139-19-1 |
DC8700 |
ODM-201(Darolutamide)
Featured
ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by transactivation assays in AR-HEK293 cells. |
1297538-32-9 |
DC12445 |
ODM-203
Featured
ODM-203 (ODM203) is a potent, selective, dual inhibitor of FGFR and VEGFR tyrosine kinases with approximately equal potency towards recombinant FGFR1, 2, 3 and 4, as well as VEGFR1, 2 and 3 (IC50=5-35 nM). |
1430723-35-5 |
DC7850 |
OF-1
Featured
OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain with Kd of 100 nM and 500 nM, respectively. |
919973-83-4 |
DC12526 |
OGG1 inhibitor O8
Featured
OGG1 inhibitor O8 is a potent, selective inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 0.22 uM, displays no significant activity against other DNA Glycosylases (NEIL1, NTH1, Fpg, IC50>50 uM).. |
350997-39-6 |