Cat. No. | Product name | CAS No. |
DC7230 |
PHA-665752
Featured
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9 nM, >50-fold selectivity for c-Met than RTKs or STKs. |
477575-56-7 |
DC5111 |
PHA-680632
Featured
PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3. |
398493-79-3 |
DC8025 |
CAY10572(PHA-767491)
Featured
PHA-767491 (CAY10572) is a potent, ATP-competitive dual Cdc7/Cdk9 inhibitor with IC50 values of 10/34 nM. |
845714-00-3 |
DC4123 |
PHA-793887
Featured
PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM, respectively. |
718630-59-2 |
DC7231 |
PHA-848125(Milciclib)
Featured
PHA-848125(Milciclib) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM; >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. |
802539-81-7 |
DC9752 |
PHCCC
Featured
PHCCC is a Group I metabotropic glutamate receptor antagonist (IC50 ~ 3 μM). |
179068-02-1 |
DC10763 |
Philanthotoxin 74 (hydrochloride)
Featured
Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. |
1227301-51-0 |
DC10645 |
Phorbol 12-myristate 13-acetate (PMA)
Featured
Phorbol 12-myristate 13-acetate (PMA) is a PKC-activating phorbol ester, increases the intracellular Ca2+ concentration ([Ca2+]i) in a dose-dependent manner, with an EC50 of 11.7 nM. |
16561-29-8 |
DC7481 |
PHT427
Featured
PHT-427 is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains of Akt and PDPK1) with Ki of 2.7 μM and 5.2 μM, respectively. |
1191951-57-1 |
DC10846 |
PHTPP
Featured
PHTPP is a pyrazolo[1,5-α]pyrimidine-based ligand that acts as a full antagonist of estrogen ERβ receptors with 36-fold selectivity over ERα. |
805239-56-9 |
DC23040 |
Jatrorrhizine
Featured
Phytochemical alkaloid found in medicinal plants. Anti-inflammatory. Exhibits neuroprotective, antioxidative and gastrointestinal modulatory activities. |
3621-38-3 |
DC7232 |
PI-103
Featured
PI103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. |
371935-74-9 |
DC9611 |
PI-1840
Featured
PI-1840 is a potent and selective inhibitor for chymotrypsin-like (CT-L) (IC50 value = 27 ± 0.14 nM) over trypsin-like and peptidylglutamyl peptide hydrolyzing (IC50 values >100 μM) activities of the proteasome. |
1401223-22-0 |
DC7628 |
PI-3065
Featured
PI-3065 is a novel potent and selective PI3K p110δ inhibitor with IC50 of 15 nM; exhibits > 100 fold selectivity against p110α, p110β, p110γ, DNA-PK and mTOR. |
955977-50-1 |
DC20036 |
PI3K/mTOR Inhibitor-2
Featured
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. Antitumor activity. |
1848242-58-9 |
DC8335 |
PQR-309(Bimiralisib)
Featured
PI3K-IN-2 is a PI3K inhibitor, inhibits pPKB and pS6 with "++++/+++(+)" in A2058 melanoma cell. |
1225037-39-7 |
DC8531 |
TASP0415914
Featured
PI3Kγ is required for for T-cell and B-cell as well as mast cell migration and degranulation. As such, these kinases are attractive targets for potential anti-infmamatory drugs. TASP0415914 has shown excellent results in cell based assays. It is orally av |
1292300-75-4 |
DC20008 |
PI3Kδ-IN-1
Featured
PI3Kδ-IN-1 is a potent, selective, and efficacious PI3Kδ inhibitor with an IC50 of 1.7 nM. |
1911564-39-0 |
DC9318 |
Piboserod
Featured
Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist. |
152811-62-6 |
DC10728 |
Pibrentasvir(ABT-530)
Featured
Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. |
1353900-92-1 |
DC8426 |
Picropodophyllin (PPP)
Featured
Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM. |
477-47-4 |
DCAPI1426 |
Pidotimod
Featured
Pidotimod is a synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses. This compound has been shown to induce dendritic cell maturation and up-regulate the expression of HLA-DR and co-stimulatory molecu |
121808-62-6 |