Cat. No. | Product name | CAS No. |
DC9505 |
Pifithrin-α (hydrobromide)
Featured
Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. |
63208-82-2 |
DC8144 |
Pifithrin-β (hydrobromide)
Featured
Pifithrin-β HBr (Cyclic Pifithrin-α HBr) is a potent p53 inhibitor with IC50 of 23 uM in an antiproliferative assay in the human ovarian carcinoma cell line, IGROV-1. |
511296-88-1 |
DC7233 |
Pifithrin-u
Featured
Pifithrin-μ is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2, and also inhibits HSP70 function and autophagy. |
64984-31-2 |
DC9661 |
PIK-293
Featured
PIK-293 is a PI3K inhibitor, mostly for PI3Kδ with IC50 of 0.24 μM, 500-, 100- and 50-fold less potent to PI3Kα/β/γ, respectively. |
900185-01-5 |
DC7234 |
PIK-294
Featured
PIK-294 is a highly selective p110δ inhibitor with IC50 of 10 nM, 1000-, 49- and 16-fold less potent to PI3Kα/β/γ, respectively. |
900185-02-6 |
DC7235 |
PIK-75
Featured
PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM. |
372196-77-5 |
DC1096 |
PIK90
Featured
PIK-90 is a potent and cell permeable inhibitor of p110α, p110β, p110γ and p110δ with IC50 of 11 nM, 350 nM, 18 nM and 58 nM, respectively. |
677338-12-4 |
DC8254 |
PIK-93
Featured
PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM; shown to inhibit PI3Kα with IC50 of 39 nM. |
593960-11-3 |
DC9747 |
PIK-III
Featured
PIK-III, which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. |
1383716-40-2 |
DC8184 |
Pilaralisib(XL-147; SAR245408)
Featured
Pilaralisib (SAR245408; XL147) is selective oral pan-PI3K inhibitor. |
934526-89-3 |
DC10047 |
PIM-447 dihydrochloride
Featured
PIM447 is novel pan-PIM kinase inhibitor, including Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase. |
1820565-69-2 |
DC8795 |
Pimavanserin(ACP-103)
Featured
Pimavanserin(ACP-103) is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.7 in the cell-based functional assay. |
706779-91-1 |
DC8243 |
Pimecrolimus
Featured
Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12. |
137071-32-0 |
DC8661 |
Pimelic Diphenylamide 106(TC-H 106)
Featured
Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I HDAC (HDAC 1, 2, and 3, with IC50 values of 150 nM , 760nM, and 370 nM, respectively), demonstrating no activity against class II HDACs. |
937039-45-7 |
DC7236 |
Pimobendan
Featured
Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM. |
74150-27-9 |
DC9815 |
Pimodivir(VX-787)
Featured
Pimodivir(VX-787) is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. |
1629869-44-8 |
DC20505 |
Pimozide
Featured
Pimozide is an antipsychotic agent that acts as an antagonist of the D2, D3, and D4 receptors and the 5-HT7 receptor, also is an inhbitor of STAT5. |
2062-78-4 |
DC12096 |
Pinacidil monohydrate (Pinacidil hydrate)
Featured
Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator. |
85371-64-8 |
DCAPI1413 |
pioglitazone hydrochloride
Featured
Pioglitazone Hydrochloride is the hydrochloride salt preparation of Pioglitazone, a specific ligand of PPAR-γ (peroxisome proliferator-activated receptor-γ). Pioglitazone is a thiazolidinedione compound described to produce antiinflammatory and antiarteri |
112529-15-4 |
DC10113 |
Pipequaline
Featured
Pipequaline (PK 8165) is a partial benzodiazepine receptor agonist with anxiolytic activity. |
77472-98-1 |
DC24186 |
Piperazine Erastin
Featured
Piperazine Erastin is an analog of Erastin, which can induces ferroptosis in cancer cells, an iron-dependent form of nonapoptotic cell death.. |
1538593-71-3 |
DC9691 |
Piperlongumine
Featured
Piperlongumine induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and normal p53. |
20069-09-4 |