Cat. No. | Product name | CAS No. |
DC21624 |
SBI-425
Featured
SBI-425 (SBI425) is a potent, selective, orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor with IC50 of 16 nM, shows high selectivity over other alkaline phosphatases including IAP and PLAP. |
1451272-71-1 |
DC21625 |
SBI-477
Featured
SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively. |
781628-99-7 |
DC11283 |
SBI993
Featured
SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability |
2073059-82-0 |
DC7599 |
SC1(Pluripotin)
Featured
SC1(Pluripotin) is a sustainer of mES self-renewal and ERK 1 inhibitor |
839707-37-8 |
DC5030 |
SC144
Featured
SC144 is an orally active small-molecule gp130 inhibitor. |
895158-95-9 |
DC21629 |
SC-236
Featured
SC-236 (SC58236) is a potent, selective, orally active inhibitor of COX-2 with IC50 of 10 nM. |
170569-86-5 |
DC7281 |
SC-514 (GK 01140)
Featured
SC-514 (GK 01140), a small molecule, is a selective inhibitor of IKK-2; does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases. |
354812-17-2 |
DC7030 |
SC-560
Featured
SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors which includes celecoxib (Celebrex™) and rofecoxib (Vioxx™). |
188817-13-2 |
DC9273 |
SC-66
Featured
SC-66 is an allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. |
871361-88-5 |
DC10636 |
SC75741
Featured
SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM. |
913822-46-5 |
DC8333 |
SC-79
Featured
SC-79 is an activator of Akt; binds to the pleckstrin homology domain of Akt. |
305834-79-1 |
DC10189 |
SCH 23390 hydrochloride
Featured
SCH 23390 hydrochloride is a potent dopamine receptor D1 antagonist with Ki values of 0.2 and 0.3 nM for the D1 and D5. |
125941-87-9 |
DC23318 |
SCH 529074
Featured
SCH 529074 is a small molecule mutant p53 reactivator that binds p53 DNA binding domain with Kd of 1-2 uM. |
922150-11-6 |
DC23823 |
Benzenesulfonamide, n-b-d-glucopyranosyl-4-(hydroxyamino)-n-[2-(2-naphthalenyloxy)ethyl]-
Featured
SCH 54292 is a potent Ras-GEF interaction inhibitor with IC50 of 0.7 uM.. |
188480-51-5 |
DC5024 |
MK-8776 (SCH 900776)
Featured
SCH 900776 is a selective Chk1 inhibitor with IC50 of 3 nM. It shows 50-fold selectivity against Chk2. Phase 2. |
891494-63-6 |
DC23626 |
SCH-28080
Featured
SCH-28080 is a potent, orally active, reversible inhibitor of gastric H+,K+-ATPase with IC50 of 20 nM. |
76081-98-6 |
DC7283 |
SCH-772984
Featured
SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively. |
942183-80-4 |
DC8737 |
SCH900776 S-isomer
Featured
SCH900776 (S-isomer) is the S-isomer form of SCH900776, which is a potent, selective and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50 = 3 nM), highly selective against Chk2 (IC50 = 1500 nM) and cyclin-dependent kinase CDK2 (IC50 |
891494-64-7 |
DCAPI1371 |
Scopine HCl
Featured
Scopine hydrochloride (6,7-Epoxytropine hydrochloride) is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock. |
85700-55-6 |
DC23080 |
Scopolamine
Featured
Scopolamine is a high affinity (nM) muscarinic antagonist. 5-HT3 receptor-responses are reversibly inhibited by Scopolamine with an IC50 of 2.09 μM. Scopolamine can cause learning and memory impairments and galantamine can reverse the symptom. It also can |
51-34-3 |
DC23060 |
Scopoletin
Featured
Scopoletin exhibits antifungal, anti-allergic, anti-aging, and hypouricemic activities, it exerts anti-RA action probably through suppressing IL-6 production from fibroblast-like synoviocytes via MAPK/PKC/CREB pathways. |
92-61-5 |
DC12667 |
SCR-1481B1(BMS-817378 tris salt)
Featured
SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor. |
1174161-86-4 |