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Cat. No. Product name CAS No.
DC21624 SBI-425 Featured

SBI-425 (SBI425) is a potent, selective, orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor with IC50 of 16 nM, shows high selectivity over other alkaline phosphatases including IAP and PLAP.

1451272-71-1
DC21625 SBI-477 Featured

SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively.

781628-99-7
DC11283 SBI993 Featured

SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability

2073059-82-0
DC7599 SC1(Pluripotin) Featured

SC1(Pluripotin) is a sustainer of mES self-renewal and ERK 1 inhibitor

839707-37-8
DC5030 SC144 Featured

SC144 is an orally active small-molecule gp130 inhibitor.

895158-95-9
DC21629 SC-236 Featured

SC-236 (SC58236) is a potent, selective, orally active inhibitor of COX-2 with IC50 of 10 nM.

170569-86-5
DC7281 SC-514 (GK 01140) Featured

SC-514 (GK 01140), a small molecule, is a selective inhibitor of IKK-2; does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.

354812-17-2
DC7030 SC-560 Featured

SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors which includes celecoxib (Celebrex™) and rofecoxib (Vioxx™).

188817-13-2
DC9273 SC-66 Featured

SC-66 is an allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination.

871361-88-5
DC10636 SC75741 Featured

SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.

913822-46-5
DC8333 SC-79 Featured

SC-79 is an activator of Akt; binds to the pleckstrin homology domain of Akt.

305834-79-1
DC10189 SCH 23390 hydrochloride Featured

SCH 23390 hydrochloride is a potent dopamine receptor D1 antagonist with Ki values of 0.2 and 0.3 nM for the D1 and D5.

125941-87-9
DC23318 SCH 529074 Featured

SCH 529074 is a small molecule mutant p53 reactivator that binds p53 DNA binding domain with Kd of 1-2 uM.

922150-11-6
DC23823 Benzenesulfonamide, n-b-d-glucopyranosyl-4-(hydroxyamino)-n-[2-(2-naphthalenyloxy)ethyl]- Featured

SCH 54292 is a potent Ras-GEF interaction inhibitor with IC50 of 0.7 uM..

188480-51-5
DC5024 MK-8776 (SCH 900776) Featured

SCH 900776 is a selective Chk1 inhibitor with IC50 of 3 nM. It shows 50-fold selectivity against Chk2. Phase 2.

891494-63-6
DC23626 SCH-28080 Featured

SCH-28080 is a potent, orally active, reversible inhibitor of gastric H+,K+-ATPase with IC50 of 20 nM.

76081-98-6
DC7283 SCH-772984 Featured

SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.

942183-80-4
DC8737 SCH900776 S-isomer Featured

SCH900776 (S-isomer) is the S-isomer form of SCH900776, which is a potent, selective and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50 = 3 nM), highly selective against Chk2 (IC50 = 1500 nM) and cyclin-dependent kinase CDK2 (IC50

891494-64-7
DCAPI1371 Scopine HCl Featured

Scopine hydrochloride (6,7-Epoxytropine hydrochloride) is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.

85700-55-6
DC23080 Scopolamine Featured

Scopolamine is a high affinity (nM) muscarinic antagonist. 5-HT3 receptor-responses are reversibly inhibited by Scopolamine with an IC50 of 2.09 μM. Scopolamine can cause learning and memory impairments and galantamine can reverse the symptom. It also can

51-34-3
DC23060 Scopoletin Featured

Scopoletin exhibits antifungal, anti-allergic, anti-aging, and hypouricemic activities, it exerts anti-RA action probably through suppressing IL-6 production from fibroblast-like synoviocytes via MAPK/PKC/CREB pathways.

92-61-5
DC12667 SCR-1481B1(BMS-817378 tris salt) Featured

SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.

1174161-86-4
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