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Cat. No. Product name CAS No.
DC8359 STF-31 Featured

STF-31 is an inhibitor of GLUT1 (IC50 = ~1 µM) that blocks glucose uptake.

724741-75-7
DC10456 STF-62247 Featured

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).

315702-99-9
DC26063 STING Agonist C11 Featured

STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.

875863-22-2
DC12505 STING agonist-4 Featured

STING agonist 4 is an amidobenzimidazole (ABZI)-based compound that functions as a STING agonist with Kd of 1.6 nM (binding of endogenous full-length STING, THP-1 cell lysates); caused dose-dependent phosphorylation of IRF3 and STING that was inhibited by the TBK1 inhibitor BX795, induced dose-dependent secretion of IFN-β with EC50 of 3.1 uM in PBMCs (18-fold more potent than cGAMP); promotes production of IFN-γ-induced protein 10 (IP-10), IL-6 and TNFα by a mechanism that is dependent on STING-mediated activation of TBK1; unlike cGAMP and DMXAA, compound 2 efficiently activates STING function while maintaining an open STING confirmation.

2138300-40-8
DC11451 STING agonist compound 1 Featured

diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.

2138299-33-7
DC10960 STING inhibitor C-176 Featured

STING inhibitor C-178 is a covalent, in vivo-active, small-molecule inhibitor of STING

314054-00-7
DC10959 STING inhibitor C-178 Featured

STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING; covalently binds to Cys91, directly targets mouse STING (mmSTING) but not human STING (hsSTING).

329198-87-0
DC10201 STK16-IN-1 Featured

STK16-IN-1 is a STK16 kinase inhibitor with an IC50 of 295 nM.

1223001-53-3
DC9844 STK321130(FLT3-IN-2) Featured

STK321130(FLT3-IN-2)is potent FLT3 inhibitor

923562-23-6
DC11264 STO-609 (acetate) Featured

STO-609 is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases (CaMKK) isoforms CaMKKα and CaMKKβ (Ki = 80 and 15 ng/ml, respectively).

1173022-21-3
DC9961 STO-609 Featured

STO-609 is a selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki values are 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively); competes for the ATP-binding site.

52029-86-4
DCAPI1552 streptomycin Featured

Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .

57-92-1
DC21709 SU 16f Featured

SU 16f is a potent and selective PDGFRβ inhibitor with IC50 of 10 nM, displays >14-fold, >229-fold and >10,000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively.

251356-45-3
DC10602 SU 4313 Featured

SU 4313 is a bioactive chemical.

186611-55-2
DC10601 SU 4942 Featured

SU 4942 is a bioactive chemical.

76086-99-2
DC10600 SU 5205 Featured

SU 5205 is a VEGFR2 inhibitor.

3476-86-6
DC10519 SU 5214 Featured

SU 5214 is a modulator of tyrosine kinase signal transduction.

186611-04-1
DC8102 SU6656 Featured

SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively).

330161-87-0
DC1093 SU11274 (PKI-SU11274) Featured

SU11274 is a selective Met inhibitor with IC50 of 10 nM.

658084-23-2
DC7302 SU14813 Featured

SU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR), Kit, and fms-like tyrosine kinase 3 (FLT-3).

627908-92-3
DC7509 SU1498 Featured

SU1498 is a selective inhibitor of the VEGFR2; inhibits Flk-1with an IC50 of value of 700 nM.

168835-82-3
DC9781 SU4312(NSC86429) Featured

SU4312(NSC86429) is a selective, cell-permeable inhibitor of VEGFR2 and PDGFR tyrosine kinases (IC50s = 0.8 and 19.4 μM, respectively).

5812-07-7
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