Cat. No. | Product name | CAS No. |
DC7366 |
Atglistatin
Featured
Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM. |
1469924-27-3 |
DC10921 |
ATH686
Featured
ATH686 (ATH-686) is a potent and selective, second-generation inhibitor of mutant FLT3 protein kinase. |
853299-52-2 |
DC8925 |
Atipamezole
Featured
Atipamezole(MPV1248) is an alpha-adrenoceptor antagonist with high affinity and selectivity for the alpha 2-receptor. |
104054-27-5 |
DC7709 |
ATN-161
Featured
ATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. |
262438-43-7 |
DCAPI1442 |
Atorvastatin Calcium
Featured
Atorvastatin Calcium |
134523-03-8 |
DCAPI1390 |
Atovaquone (Atavaquone)
Featured
Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia. |
95233-18-4 |
DC23072 |
Atractylenolide II
Featured
Atractylenolide II has antiinflammatory activity, it can inhibit platelets activities and thrombus formation. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation ,ERK and Akt inactivation, p53 dependent, it also has antimelanoma effe |
73069-14-4 |
DC23073 |
Atractylenolide III
Featured
Atractylenolide III, a potential house dust mite control agent, has neuroprotection, gastroprotective, anti-cancer, and anti-inflammatory activities, it also may control immunological reactions by regulating the cellular functions of IL-6 in mast cells. |
73030-71-4 |
DC23059 |
Atractylon
Featured
Atractylone has inhibitory effects on mast cell-mediated allergic reactions, it regulates the degranulation of mast cell, proves its potential in the treatment of mast cell-mediated allergic reactions. |
6989-21-5 |
DCAPI1288 |
Atracurium besylate
Featured
Atracurium besylate is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents. |
64228-81-5 |
DC10018 |
Atrasentan hydrochloride
Featured
Atrasentan Hcl(A-147627) is an endothelin antagonist receptor (IC50=0.0551 nM, ETA) being developed for the treatment of prostate cancer. |
195733-43-8 |
DC10552 |
AU1235
Featured
AU1235 is an adamantyl urea inhibitor of Mycobacterium tuberculosis. |
1338780-86-1 |
DC21865 |
Aumitin
Featured
Aumitin is a novel potent autophagy inhibitor with IC50 of 124 and 244 nM against starvation- and rapamycin- induced autophagy respectively, targets mitochondrial complex I. |
946293-78-3 |
DC12428 |
AUNP-12
Featured
AUNP-12 (Aurigene-012) is a PD-1 inhibitor peptide, blocks the PD-1/PD-L1, PD-1/PD-L2 and PD-L1/CD80 pathways. |
1353563-85-5 |
DC10138 |
Auristatin E
Featured
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. |
160800-57-7 |
DC7964 |
Aurora A Inhibitor I
Featured
Aurora A inhibitor I is a selective Aurora A inhibitor (Aurora A: IC50=0.0034 μM; Aurora B IC50=3.4 μM), (B/A ratio=1000). |
1158838-45-9 |
DC26118 |
AKI-7169(Aurora Kinase Inhibitor III)
Featured
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM). |
879127-16-9 |
DC11999 |
AUT-1
Featured
AUT-1 is a novel specific, cell permeant modulator of Kv3 channels with EC50 of 4.7 and 4.9 uM for Kv3.1b and Kv3.2a, respectively. |
1311136-84-1 |
DC10548 |
Auten-99
Featured
Auten-99 is a novel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14), acrossing the blood-brain barrier and exerting potent neuroprotective effects. |
1049780-58-6 |
DC10461 |
Autophinib
Featured
Autophinib is a novel potent autophagy inhibitor, inhibiting autophagy induced by starvation or Rapamycin by targeting the lipid kinase VPS34. |
1644443-47-9 |
DC5202 |
Luminespib (NVP-AUY922)
Featured
AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 1/2. |
747412-49-3 |
DC8799 |
Avanafil(TA-1790)
Featured
Avanafil(TA-1790) is a potent and highly selective phosphodiesterase-5(PDE-5) inhibitor(IC50=5.2 nM) for erectile dysfunction; lower selectivity against PDE1, PDE6, and PDE11. |
330784-47-9 |