Cat. No. | Product name | CAS No. |
DC11174 |
ASP7657
Featured
ASP7657 (ASP-7657) is a potent, selective, orally active prostaglandin EP4 receptor antagonist with Ki values of 6.02 nM and 2.21 nM for rat and human EP4 receptors, resepctively. |
1196045-28-9 |
DC10588 |
ASP-9521
Featured
ASP-9521 is a potent, selective and orally available AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3. |
1126084-37-4 |
DC11163 |
AST-3424
Featured
AST-3424 (OBI-3424, TH-3424) is a first-in-class, novel prodrug that selectively targets cancers overexpressing the enzyme AKR1C3, OBI-3424 is a highly selective prodrug that is converted by AKR1C3 to a DNA alkylating agent. |
2097713-68-1 |
DC8641 |
Astragaloside A
Featured
Astragaloside A, also known as astragaloside IV, is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. |
83207-58-3 |
DC11447 |
Astragaloside IV
Featured
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. |
84687-43-4 |
DC20695 |
ASTX660(Tolinapant)
Featured
ASTX660 is a novel potent IAP antagonist that targets the BIR3 domain of cIAP1/2 and XIAP with IC50 of 12 nM and <40 nM. |
1799328-86-1 |
DC7361 |
Asunaprevir
Featured
Asunaprevir (BMS-650032) is a potent hepatitis C virus (HCV) NS3 protease inhibitor. |
630420-16-5 |
DC20080 |
AT-1002
Featured
AT-1002, a 6-mer synthetic peptide, is a tight junction regulator and absorption enhancer. |
835872-35-0 |
DC26065 |
AT-127
Featured
AT-127 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM. |
2099680-72-3 |
DC20699 |
AT-130
Featured
AT-130 is a potent inhibitor of HBV capsid assembly, inhibits wild-type HBV replication with IC50 of 2.4 uM. |
211364-06-6 |
DC7362 |
AT13148
Featured
AT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity; AKT, p70S6K, PKA, ROCK, and SGK inhibitor. |
1056901-62-2 |
DC8167 |
Onalespib(AT13387,ATI13387X)
Featured
AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells, displays a long duration of anti-tumor activity. |
912999-49-6 |
DC7363 |
AT-406
Featured
AT-406 (formerly known as SM-406) is an orally bioavailable potent IAP (inhibitor of apoptosis protein) of XIAP, cIAP1, and cIAP2 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, respectively. |
1071992-57-8 |
DC7364 |
AT-56
Featured
AT-56 is a selective, competitive, and highly bioavailable inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) with a Ki value of 75 µM. |
162640-98-4 |
DC9676 |
AT7519
Featured
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM; less potent to CDK3 and little active to CDK7. |
844442-38-2 |
DC1025 |
AT7519 HCL
Featured
AT7519 is a novel multi-CDK inhibitor for CDK1/cyclin B, CDK2/Cyclin A, CDK3/Cyclin E, CDK4/Cyclin D1, CDK5/p35 and CDK6/Cyclin D3 with IC50 of 210 nM, 47 nM, 360 nM, 100 nM, 13 nM and 170 nM, respectively. |
902135-91-5 |
DC9335 |
AT7867
Featured
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. |
857531-00-1 |
DC7070 |
AT9283
Featured
AT9283 is a small molecule a multi-targeted inhibitor with of 4, 1.2, 1.1 and approximate 3 nM for Bcr-Abl(T3151), Jak2 and Jak3, aurora A and B, respectively. |
896466-04-9 |
DC11889 |
Atabecestat
Featured
Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent, oral beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease. |
1200493-78-2 |
DC21121 |
Ataciguat
Featured
Ataciguat (HMR-1766) is a potent, specific soluble guanylate cyclase (sGC) activator with EC50 of 0.51 uM, preferentially activates the NO-insensitive heme-oxidized form of sGC. |
254877-67-3 |
DC3150 |
Atazanavir
Featured
Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. |
198904-31-3 |
DC7365 |
ATB-346
Featured
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity. |
1226895-20-0 |