| DC5144 |
1-Azakenpaullone
Featured
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1-Azakenpaullone is a potent and ATP-competitive GSK-3β (glycogen synthase kinase-3β) inhibitor (IC₅₀ = 18 nM). |
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| DC10674 |
1-EBIO
Featured
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1-EBIO is an Epithelial KCa channel activator. Promotes ESC differentiation into cardiomyocytes. |
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| DC12129 |
1F-Fructofuranosylnystose
Featured
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1F-Fructofuranosylnystose can be used in the synthesis of Fructooligosaccharides (FOSs). Fructooligosaccharides exhibit lots of beneficial effects on our health and have been used as food ingredients. |
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| DC9220 |
1-Kestose
Featured
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1-Kestose is a fructo-oligosaccharide (FOS) with prebiotic properties, and is a polymer of d-fructose joined by β(2→1) linkages and terminated with a d-glucose molecule linked to fructose by an α(1→2) bond as in sucrose. |
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| DC8835 |
1-Methoxy PMS
Featured
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1-Methoxy PMS is an electron mediator for NAD(P)H-tetrazolium salt. |
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| DC8649 |
1-Methyl-7-nitroisatoic anhydride
Featured
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1-methyl-7-nitroisatoic anhydride is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity. |
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| DC9281 |
1-NA-PP1
Featured
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1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). |
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| DC10889 |
1-NA-PP 1 hydrochloride
Featured
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1-Naphthyl PP1(1-NA-PP1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. |
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| DC8640 |
1-NM-PP1
Featured
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1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. |
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| DCAPI1534 |
Alfacalcidol
Featured
|
1α-Hydroxyvitamin D3 is a form of vitamin D that helps the body absorb calcium from food. |
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| DCAPI1471 |
Arabinofuranosylcytosine
Featured
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1-β-D-Arabinofuranosylcytosine, a cytosine analogue, inhibits DNA polymerases α, δ, and ε, and RNA polymerases resulting in suppression of DNA synthesis and repair. 1-β-D-Arabinofuranosylcytosine acts as an antimetabolic agent which is responsible for dam |
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| DC20140 |
Cyclouridine
Featured
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2,2'-Cyclouridine is a research tool for antiviral and anticancer studies. |
|
| DC7972 |
2,4-Pyrimidinediamine with linker
Featured
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2,4-Pyrimidinediamine with linker is a patent compound in WO2013055780A1, Page 71; multikinase inhibitor and has a -NH2 terminal linker for further synthesis. |
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| DC9647 |
20-Deoxyingenol
Featured
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20-Deoxyingenol is a natural compound. |
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| DC9655 |
20-O-Acetylingenol-3-angelate
Featured
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20-O-Acetylingenol-3-angelate is a diterpene ester that has been found in E. peplus and a derivative of ingenol-3-angelate |
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| DC10666 |
MDK-7933
Featured
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MDK-7933, also known as HDAC8-IN-1, is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). MDK-7933 was first reported in ChemMedChem. 2012 Oct;7(10):1815-24. MDK-7933 has CAS#1417997-93-3. |
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| DC12367 |
Cyclic guanosine monophosphate-adenosine monophosphate
Featured
|
2'3'-cGAMP has been used to identify small compounds capable of binding human stimulator of interferon genes (STING). It is also used to study type I interferon response to cytosolic DNA. |
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| DC9802 |
23-hydroxy butulinic acid (23-HBA)
Featured
|
23-hydroxy butulinic acid (23-HBA) is a potent angiogenesis inhibitor. |
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| DC12231 |
25-Hydroxycholesterol
Featured
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25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells. |
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| DC22088 |
2BAct
Featured
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2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays. |
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| DC20158 |
2'-Deoxyadenosine monohydrate
Featured
|
2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis. |
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| DC20144 |
2-Furoic acid
Featured
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2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats. |
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| DC20137 |
2'-Hydroxy-4'-methylacetophenone
Featured
|
2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. It could be used in the preparation of 4’-methyl-2’-[(p-tolylsulfonyl) oxy] acetophenone. |
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| DC9044 |
2-Methoxyestradiol
Featured
|
2-methoxyestradiol (2ME2; NSC-659853) is a natural metabolite of estrogen that is known to inhibit HIF-1 alpha with an IC50 of 0.71 ± 0.11 μM for the inhibition of BPAEC migration. |
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| DC12356 |
2-NBDG
Featured
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2-NBDG is a fluorescent indicator for direct glucose uptake measurement and also is an indicator of cell viability. |
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| DC20134 |
2-Phenylethanol
Featured
|
2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid that is slightly soluble in water. It has a pleasant floral odor and also an autoantibiotic produced by |
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| DC10014 |
2-PMPA(NAALADaseinhibitor)
Featured
|
2-PMPA is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
|
| DC8567 |
3-(4-Pyridyl)
Featured
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3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay |
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| DC9892 |
3,3'-Diindolylmethane
Featured
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3,3'-Diindolylmethane(DIM) is a major digestive product of indole-3-carbinol, a potential anticancer component of cruciferous vegetables. |
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| DC23033 |
Isochlorogenic acid B
Featured
|
3,4-Dicaffeoylquinic acid (3,4-DCQA) is a polyphenol with diverse biological activities. |
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