| DC20128 |
3,4-Dimethoxycinnamic acid (O-Methylferulic acid)
Featured
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3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effe |
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| DC23041 |
Isochlorogenic acid A
Featured
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3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants.It has antioxidant, anti-inflammatory, and antiviral biological activities. |
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| DC10861 |
3BDO
Featured
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3BDO is a new mTOR activator which can also inhibit autophagy. |
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| DC9249 |
3-Cyano-7-ethoxycoumarin
Featured
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3-Cyano-7-ethoxycoumarin is a fluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin. |
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| DC5190 |
3-Deazaneplanocin A (DZNep）
Featured
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3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. |
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| DC12491 |
3-methyl toxoflavin
Featured
|
3-methyl toxoflavin. Toxoflavin acts as a pH indicator, changing between yellow and colorless at pH 10.5. |
|
| DC7348 |
3-Methyladenine
Featured
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3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM. |
|
| DC10452 |
3PO
Featured
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3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor; reduces glycolytic flux and suppresses glucose uptake. |
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| DC12664 |
3-pyridine toxoflavin
Featured
|
3-pyridine toxoflavin is an impurity of toxoflavin. |
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| DC10616 |
3-TYP
Featured
|
3-TYP is a selective SIRT3 inhibitor. |
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| DC20186 |
4-Butylresorcinol
Featured
|
4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent. |
|
| DC21978 |
4-CPPC
Featured
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4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1. |
|
| DC8245 |
4E1rcat
Featured
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4E1RCat is an inhibitor of protein translation that has been shown to prevent eIF4E:eIF4G and eIF4E:4E-BP1 interaction. |
|
| DC10415 |
4E2RCat
Featured
|
4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM. |
|
| DC7349 |
4EGI-1
Featured
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4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM. |
|
| DC9978 |
4-oxo-4-HPR
Featured
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4-oxo-4-HPR is a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. |
|
| DC10090 |
4-P-PDOT
Featured
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4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype. |
|
| DC10689 |
4P-PDOT
Featured
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4P-PDOT, also known as 4-phenyl-2- propionamidotetralin, is a MT2-receptor-specific antagonist. MT2 melatonin receptor may be a novel target for analgesic drug development. |
|
| DC7592 |
4SC-202
Featured
|
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an acc |
|
| DC10037 |
4μ8C
Featured
|
4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM. |
|
| DC10877 |
5,3-AB-CHMFUPPYCA
Featured
|
5,3-AB-CHMFUPPYCA is an analytical reference standard that is structurally classified as a synthetic cannabinoid. |
|
| DCAPI1525 |
5-Azacytidine
Featured
|
5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t |
|
| DC9371 |
5-FAM SE
Featured
|
5-FAM SE is a single isomer, it is one of the most popular green fluorescent reagents used for labeling peptides, proteins and nucleotides. |
|
| DC12703 |
5-Formyl-2-pyrimidinecarbonitrile
Featured
|
5-Formyl-2-pyrimidinecarbonitrile is a chemical intermidate.. |
|
| DC7494 |
SB-242084 HCl
Featured
|
5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2Breceptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity. |
|
| DC5179 |
5-IODOTUBERCIDIN
Featured
|
5-Iodotubercidin (Itu) has been shown to inhibit mitogen-activated protein kinase (ERK2) (Ki = 525 nM), adenosine kinase (ADK) (Ki = 30 nM), casein kinases 1 & 2 (CSNK1A1 & CSNK2A1), protein kinase A (PKA) and insulin receptor kinase (IC50 ranging from 0. |
|
| DC7604 |
FAI (5S rRNA modificator)
Featured
|
5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification. |
|
| DC10187 |
666-15
Featured
|
666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM. |
|
| DC9372 |
6-FAM SE
Featured
|
6-FAM SE is another isomer of carboxyfluorescein. |
|
| DC7736 |
6H05
Featured
|
6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C). |
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