Cat. No. | Product name | CAS No. |
DC20781 |
BI 671800
Featured
BI 671800 is a potent, oral prostaglandin D2 receptor (CRTH2) antagonist for treatment of asthma.. |
1093108-50-9 |
DC23560 |
BI01383298
Featured
BI01383298 (BI-01383298) is a potent, specific sodium-citrate co-transporter SLC13A5 (NaCT, INDY), highly selective over other family members and other transporters.. |
2227549-00-8 |
DC12406 |
BI-0314
Featured
BI-0314 (BI0314) is an allosteric activator of protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) with potency of 56% at 500 uM, displays no activity against hPTP1B and hTCPTP. |
2244560-46-9 |
DC20775 |
BI-1347
Featured
BI-1347 is a potent, selective inhibitor of CDK8/cyclinC with IC50 of 1 nM. |
2163056-91-3 |
DC7083 |
Bi 2536
Featured
BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM). |
755038-02-9 |
DC20779 |
BI-3802
Featured
BI-3802 (BI3802) is a highly potent and efficacious BCL6 degrader that potently inhibits the interaction of the BTB/POZ domain of BCL6 with several co-repressors in vitro with IC50 of <3 nM. |
2166387-65-9 |
DC23310 |
BI-3812
Featured
BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity. |
2166387-64-8 |
DC22310 |
BI-4464
Featured
BI-4464 (BI 4464) is a potent, highly selective, ATP competitive inhibitor of Focal adhesion tyrosine kinase (PTK2/FAK) with IC50 of 17 nM.. |
1227948-02-8 |
DC7107 |
BI-78D3
Featured
BI-78D3 is a competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. |
883065-90-5 |
DC8401 |
BI-847325
Featured
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1. |
1207293-36-4 |
DC9888 |
BI-9564
Featured
BI-9564 is a selective, and cell-permeable BRD9 BD inhibitor, with Kd of 5.9 nM for BRD9, and IC50 of > 100 μM for BET family. |
1883429-22-8 |
DC10404 |
BIA 10-2474
Featured
BIA 10-2474 is an inhibitor of fatty acid amide hydrolase (FAAH) with IC50 values of 50 to 70mg/kg in various rat brain regions. |
1233855-46-3 |
DC20788 |
BIBO-3304
Featured
BIBO 3304 is a potent, selective, nonpeptide neuropeptide Y Y1 receptor antagonist with IC50 of 0.38 and 0.72 nM for human and the rat Y1 receptor, respectively. |
191868-14-1 |
DC7085 |
BIBR-1532
Featured
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM. |
321674-73-1 |
DCAPI1112 |
BIBR 953(Dabigatran)
Featured
BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. |
211914-51-1 |
DC1010 |
BIBR-1048 (Dabigatran etexilate)
Featured
BIBR-1048 (Dabigatran) is an anticoagulant from the class of the direct thrombin inhibitors. |
211915-06-9 |
DC9670 |
BIBS39
Featured
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. |
133085-33-3 |
DC1024 |
Afatinib (BIBW2992)
Featured
BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively. |
439081-18-2 |
DC10890 |
Bictegravir
Featured
Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. |
1611493-60-7 |
DC7098 |
BI-D1870
Featured
BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC50s are 31 nM, 24 nM, 18 nM, 15 nM, respectively. |
501437-28-1 |
DC7086 |
BIIB021(CNF2024)
Featured
BIIB021(CNF2024) is an orally available, fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectively. |
848695-25-0 |
DC8263 |
Bikinin
Featured
Bikinin is a strong activator of brassinosteroid (BR) signaling. |
188011-69-0 |