DC7346 |
Cephalosporin C zinc salt
Featured
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Cephalosporin C zinc salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. |
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DC9649 |
Cephalotaxlen
Featured
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Cephalotaxine is an antiviral as well as antitumor agent. |
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DC9765 |
CERC-501(LY-2456302,Aticaprant)
Featured
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CERC-501(LY-2456302) is a potent, selective antagonist of the kappa opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR), respectively. |
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DC7814 |
Cerdulatinib(PRT-062070; PRT2070)
Featured
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Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor. |
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DC9500 |
Cevimeline (hydrochloride hemihydrate)
Featured
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Cevimeline hydrochloride hemihydrate, a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome. |
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DC10440 |
Namodenoson (CF-102)
Featured
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CF-102(2-Cl-IB-MECA) is a selective A3 adenosine receptor agonist (Ki = 0.33 nM). Displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively.
target: A3 adenosine receptor agonist; |
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DC10069 |
CFI-400437
Featured
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CFI-400437 is potent against PLK4 (IC50 = 0.6 nM) and selective against other members of the PLK family (>10 uM). |
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DC22809 |
c-FMS-IN-8
Featured
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c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.. |
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DC7039 |
CFTR Inhibitor II
Featured
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CFTR Inhibitor II is a cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed (< 1 min; 95% inhibition at 50 µM; Ki = 4.3 µM in CFTR-expressing FRT cells. |
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DC12580 |
CG-806
Featured
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CG-806 (CG806, CG'806) is a novel potent, pan-FLT3/BTK multi-kinase inhibitor with impressive inhibition of leukemic cell proliferation with IC50 at sub-nanomolar or low nanomolar levels. |
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DC7380 |
CGI-1746
Featured
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CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. |
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DC7101 |
CGK733
Featured
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CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM. |
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DC10843 |
CGP 52432
Featured
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CGP 52432 is a potent, selective GABAB receptor antagonist (IC50 = 85 nM). |
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DC7381 |
CGP-57380
Featured
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CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 (IC50 = 2.2 μM) with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. |
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DC10722 |
CGP-71683A
Featured
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CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity. |
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DC23919 |
CGP-42112
Featured
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CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM. |
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DC8471 |
CGS 21680 hydrochloride
Featured
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CGS 21680 hydrochloride is an A2A adenosine receptor agonist (Ki = 27 nM). |
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DC7939 |
CH-223191
Featured
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CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. |
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DC7102 |
CH5132799
Featured
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CH5132799 selectively inhibits class I PI3Ks, such as PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ with IC50 values of 0.014, 0.12, 0.50, and 0.36 uM, respectively; shows less inhibition of class II PI3Ks, class III PI3ks, and mTOR. |
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DC8418 |
CH5183284 (Debio-1347)
Featured
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CH5183284 is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1. |
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DC7383 |
CH5424802(Alectinib)
Featured
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CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. |
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DC8728 |
CH5424802(Alectinib HCl)
Featured
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CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. |
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DC22054 |
CH5447240
Featured
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CH5447240 is a novel potent, selective, orally active hPTHR1 agonist with EC20 of 3.0 nM and EC50 of 12 nM. |
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DC12415 |
CH7057288
Featured
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CH7057288 (CH-7057288) is a novel potent and selective pan-TRK inhibitor with IC50 of 1.1/7.8/5.1 nM for TRKA/TRKB/TRKC, respectively. |
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DC12545 |
CHDI-390576
Featured
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CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor with IC50 of 54/60/31/50 nM for HDAC4/5/7/9, respectively. |
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DC23101 |
Chelerythrine chloride
Featured
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Chelerythrine is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. |
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DC20266 |
Chelerythrine
Featured
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Chelerythrine is a well-known protein kinase C inhibitor, can inhibit telomerase activity, it also can block the human P2X 7 receptor. |
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DC20100 |
Chelidonic acid
Featured
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Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blo |
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DC21405 |
Chetomin
Featured
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Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells d |
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DC7978 |
Tucidinostat(Chidamide)
Featured
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Chidamide is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM). |
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