Cat. No. | Product name | CAS No. |
DC8830 |
Betahistine
Featured
Betahistine is a strong affinity histamine H3 receptor antagonist and weak affinity agonist of histamine H1 receptors. |
5638-76-6 |
DC7905 |
beta-Lapachone (ARQ-501, CO-501)
Featured
Beta-Lapachone is a selective DNA topoisomerase I inhibitor, exhibiting no inhibitory activities against DNA topoisomerase II or ligase. Phase 2. |
4707-32-8 |
DC11105 |
Umibecestat
Featured
beta-secretase inhibitor. |
1387560-01-1 |
DC11566 |
BETd-260
Featured
BETd-260 (ZBC260, BETd260) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
2093388-62-4 |
DC7373 |
Betrixaban
Featured
Betrixaban (PRT-054021) is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a). |
330942-05-7 |
DC11483 |
Betrixaban maleate
Featured
Betrixaban (PRT-054021) is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a). |
936539-80-9 |
DC9832 |
Betulinic acid
Featured
Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells, also is a inhibitor of HIV-1 with EC50 of 1.4 μ M. |
472-15-1 |
DC23068 |
Liquidambaric acid
Featured
Betulonic acid has anti-cancer , anti-HIV,hepatoprotective and anti-inflammatory activities, it has antiviral activity against herpes simplex virus, it also suppresses ECHO 6 virus reproduction. |
4481-62-3 |
DC9643 |
Bevirimat(PA-457)
Featured
Bevirimat(YK FH312; FH11327; MPC-4326) is an anti-HIV drug derived from a betulinic acid-like compound; is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. |
174022-42-5 |
DC8186 |
Bexagliflozin3
Featured
Bexagliflozin is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. |
1118567-05-7 |
DC8786 |
NVP-BEZ235 Tosylate
Featured
BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM. |
1028385-32-1 |
DC3136 |
NVP-BEZ235
Featured
BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM. |
915019-65-7 |
DC12131 |
BF-227(E/Z)
Featured
BF 227 is a candidate for an amyloid imaging probe for PET, with a Ki of 4.3 nM for Aβ1-42 fibrils. |
845647-80-5 |
DC9956 |
BFH772
Featured
BFH772 is a potent oral VEGFR2 inhibitor, which is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. |
890128-81-1 |
DC8310 |
BG-45
Featured
BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 µM, respectively). |
926259-99-6 |
DC10059 |
BGG463
Featured
BGG463 can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively. |
890129-26-7 |
DC5194 |
NVP-BGJ398(Infigratinib)
Featured
BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2. |
872511-34-7 |
DC8571 |
BGP-15
Featured
BGP-15 is a PARP inhibitor and insulin sensitizer. |
66611-37-8 |
DC9695 |
BH3I-1
Featured
BH3I-1 is a cell permeable BH3 mimetic that binds to Bcl-xL. BH3I-1 is an inhibitor of Bcl-xL. |
300817-68-9 |
DC21546 |
BI-1467335 HCl
Featured
BI 1467335 (PXS-4728A, PXS-4728) is a potent, selective, orally active SSAO/VAP-1 (AOC3) inhibitor with IC50 of 5 nM; displays >500-fold selective for VAP-1/SSAO over all the related human amine oxidases; diminishes leukocyte rolling and adherence induced by CXCL1/KC, also inhibits the migration of neutrophils to the lungs in response to LPS, Klebsiella pneumoniae lung infection and CLP induced sepsis. |
1478364-68-9 |
DC22021 |
BI 167107
Featured
BI 167107 is a highly potent agonist of the β2 adrenergic receptor (β2AR) and β1AR (IC50=3.2 nM) and shows some activity as α1A antagonist (IC50 = 32 nM). |
1202235-68-4 |
DC11389 |
BI 409306
Featured
BI 409306 is an inhibitor of phosphodisterase 9A(PDE9A). |
1189767-28-9 |