| DC8116 |
Tosedostat (CHR2797)
Featured
|
CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N). |
|
| DC9460 |
CHR-6494
Featured
|
CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. |
|
| DC8139 |
GMX1778(CHS-828)
Featured
|
CHS-828 is a pyridyl cyanoguanidine anti-tumor agent that has been identified as a competitive inhibitor of Nampt as well as an inhibitor of NF-κB pathway activity. |
|
| DC2088 |
CI-1040 (PD184352)
Featured
|
CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM. |
|
| DC21463 |
CI-976
Featured
|
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM. |
|
| DC2060 |
CI994 (Tacedinaline)
Featured
|
CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM. |
|
| DC12285 |
CID 1375606
Featured
|
CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. |
|
| DC10873 |
CID16020046
Featured
|
CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM. |
|
| DC7253 |
CID-2011756
Featured
|
CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells. |
|
| DC8849 |
CID-2858522
Featured
|
CID-2858522 is a selectively inhibits protein kinase C (PKC)-induced activation of the NF-κB pathway (IC50 < 0.1 μM for PMA-stimulated IL-8 production). |
|
| DC9955 |
BCL6 inhibitor(CID5721353)
Featured
|
CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor). |
|
| DC7385 |
CID-755673
Featured
|
CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM; exhibits selective PKD1 inhibition when compared with AKT, PLK1, CAK, CAMKIIα, and PKC isoforms. |
|
| DC7976 |
CID 797718
Featured
|
CID-797718 is a compound with unknown details. |
|
| DCAPI1021 |
Cidofovir(Vistide)
Featured
|
Cidofovir(Vistide) |
|
| DC10839 |
CIL56(CA3)
Featured
|
CIL56 is a small molecule that induces cellular ferroptosis through production of iron-dependent reactive oxygen species (ROS). |
|
| DC9325 |
Cilazapril (monohydrate)
Featured
|
Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
|
|
| DC7561 |
Cilengitide (TFA salt)
Featured
|
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2. |
|
| DC9875 |
Ciliobrevin A(HPI4)
Featured
|
Ciliobrevin A(HPI-4) is a Hedgehog pathway inhibitor and ciliogenesis inhibitor. |
|
| DC20341 |
Ciliobrevin D
Featured
|
Ciliobrevin D is a cell-permeable, reversible, specific inhibitor of cytoplasmic dynein, blocks dynein-dependent microtubule gliding and ATPase activity while sparing kinesin dependent cellular trafficking. |
|
| DC9160 |
Cilnidipine
Featured
|
Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity. |
|
| DC10868 |
Cilofexor
Featured
|
Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models. |
|
| DC8801 |
Cinacalcet (AMG-073)
Featured
|
Cinacalcet(AMG-073) is an orally active, second-generation calcimimetic compound; AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism. |
|
| DC12369 |
Cinaciguat (hydrochloride)
Featured
|
Cinaciguat is an activator of sGC that binds to a regulatory site, resulting in activation in an NO-independent manner (Kd = 3.2 nM). |
|
| DC20093 |
Cinchonine ((8R,9S)-Cinchonine; LA40221)
Featured
|
Cinchonine is a natural compound present in Cinchona bark. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. |
|
| DC9896 |
Cinnarizine
Featured
|
Cinnarizine is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker. |
|
| DCH-062 |
Cinobufotalin
Featured
|
Cinobufotalin is a steroid glycoside originally isolated from the Asiatic toad (B. gargarizans) and has diverse biological activities. |
|
| DC22295 |
Cintirorgon sodium
Featured
|
Cintirorgon (LYC-55716) is novel oral RAR-related orphan receptor γ (RORγ) agonist. |
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|
| DC22329 |
Cintirorgon
Featured
|
Cintirorgon (LYC-55716) is novel oral RAR-related orphan receptor γ (RORγ) agonist. |
|
| DCAPI1372 |
Ciprofloxacin (Cipro)
Featured
|
Ciprofloxacin (Bay-09867) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. |
|
| DC2062 |
Ciproxifan (FUB-359)
Featured
|
Ciproxifan is an antagonists of H3-type histamine receptors. |
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