DC12528 |
CDK9 inhibitor HH1
Featured
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CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor.. |
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DC20335 |
CDK9-IN-8
Featured
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CDK9-IN-8 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition. |
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DC23138 |
CDK-I73
Featured
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CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM. |
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DC9390 |
CDK-IN-2
Featured
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CDK-IN-2 is a potent and sepecific CDK inhibitor. |
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DC11393 |
CDM-NAG
Featured
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CDM-NAG is a useful tool compound to deliver the siRNA. |
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DC10948 |
CDN1163
Featured
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CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers. |
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DC23463 |
CDPPB
Featured
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CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively. |
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DC20336 |
CE3F4
Featured
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CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
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DC20987 |
Cedazuridine
Featured
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Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies.. |
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DC3170 |
Cediranib
Featured
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Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor with IC50 of 0.5 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM. |
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DC8067 |
Cefozopran
Featured
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Cefozopran (SCE-2787) is a new parenteral cephalosporin, against experimental infections in mice. |
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DCAPI1155 |
Celastrol
Featured
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Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. |
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DCAPI1491 |
Celecoxib
Featured
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Celecoxib is a selective Cox-2 inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LM |
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DC7568 |
Z-DEVD-FMK
Featured
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Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo. |
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DC9923 |
CeMMEC1
Featured
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CeMMEC1 is a novel potent inhibitor of the second bromodomain of TAF1, binding neither the first nor the second bromodomain of BRD4. |
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DC10316 |
Cenicriviroc
Featured
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Cenicriviroc is an orally active, dual CCR2/CCR5 antagonist, and displays potent anti-inflammatory and aninfective activity. |
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DC10010 |
Centrinone
Featured
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Centrinone is a selective and reversible inhibitor of polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole/centrosome assembly. |
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DC8138 |
CEP-28122
Featured
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CEP-28122 is a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. |
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DC8196 |
CEP-32496
Featured
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CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. |
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DC7099 |
CEP33779
Featured
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CEP33779(< 3 μM) inhibits phosphorylation of downstream target signal transducer and activator of transcription 5(pSTAT5) of JAK2 in a concentration dependent manner in HEL92 cells. |
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DC8009 |
CEP-37440
Featured
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CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma). |
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DC10337 |
CEP-40783
Featured
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CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. |
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DC7347 |
Cephalosporin C Na salt
Featured
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Cephalosporin C Na salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. |
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DC7346 |
Cephalosporin C zinc salt
Featured
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Cephalosporin C zinc salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. |
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DC9649 |
Cephalotaxlen
Featured
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Cephalotaxine is an antiviral as well as antitumor agent. |
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DC9765 |
CERC-501(LY-2456302,Aticaprant)
Featured
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CERC-501(LY-2456302) is a potent, selective antagonist of the kappa opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR), respectively. |
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DC7814 |
Cerdulatinib(PRT-062070; PRT2070)
Featured
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Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor. |
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DC9500 |
Cevimeline (hydrochloride hemihydrate)
Featured
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Cevimeline hydrochloride hemihydrate, a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome. |
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DC10440 |
Namodenoson (CF-102)
Featured
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CF-102(2-Cl-IB-MECA) is a selective A3 adenosine receptor agonist (Ki = 0.33 nM). Displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively.
target: A3 adenosine receptor agonist; |
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DC10069 |
CFI-400437
Featured
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CFI-400437 is potent against PLK4 (IC50 = 0.6 nM) and selective against other members of the PLK family (>10 uM). |
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