| DC20297 |
6-Hydroxy-DL-DOPA
Featured
|
6-Hydroxy-DL-DOPA is a small-molecule that disrupts with RAD52 oligomerization, inhibits ssDNA binding by RAD52 with IC50 of 1.1 uM and by RAD52 (1 209) with IC50 of 1.6 uM. |
|
| DC10854 |
6-MITC
Featured
|
6-MITC is an inhibitor of viability of both PANC-1 and BxPC-3 cells. It also acts as an inhibitor of the expression of CSC signaling molecule SOX2. |
|
| DC7925 |
GTPL-5846 (6-OAU)
Featured
|
6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay. |
|
| DC8953 |
6-TG/Thioguanine
Featured
|
6-Thioguanine(6-TG) belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites; it is a purine analogue of the nucleobase guanine. |
|
| DC7876 |
7ACC2
Featured
|
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells. |
|
| DC10855 |
7-Epi 10-Desacetyl Paclitaxel
Featured
|
7-Epi 10-Desacetyl Paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells. |
|
| DC10856 |
7-Epipaclitaxel
Featured
|
7-epi-Taxol is a paclitaxel binds to tubulin, interfering with the normal function of microtubule. |
|
| DC8388 |
8-Bromo-cAMP
Featured
|
8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator. |
|
| DC26033 |
8-Hydroxy-efavirenz
Featured
|
8-Hydroxy-efavirenz is the primary metabolite of the antiretroviral drug Efavirenz, stimulates the glycolytic flux in cultured rat astrocytes. |
|
| DC10537 |
8-OH-DPAT
Featured
|
8-OH-DPAT is a research chemical of the aminotetralin chemical class and has been widely used to study the function of the 5-HT1A receptor. |
|
| DC9628 |
A 419259 (trihydrochloride)
Featured
|
A 419259 3Hcl is an apoptosis inducing agent that inhibits Src family kinases (c-Src). |
|
| DC8020 |
A77-01
Featured
|
A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM. |
|
| DC7038 |
A 922500
Featured
|
A 922500 is a potent, selective, and orally bioavailable DGAT-1 inhibitor with IC50 values of 7 nM and 24 nM for human and mouse DGAT-1 respectively. |
|
| DC22873 |
TM2 115
Featured
|
A BIX-01294 derivative that inhibit malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death. |
|
| DC23922 |
Cercosporamide
Featured
|
A broad-spectrum natural antifungal compound that acts as a selective and highly potent fungal Pkc1 kinase inhibitor. |
|
| DC22519 |
Norverapamil hydrochloride
Featured
|
Norverapamil HCl is a calcium channel blocker. It is the main active metabolite of verapamil. |
|
| DC22345 |
Penthiopyrad
Featured
|
A carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps. |
|
| DC22489 |
Acebutolol hydrochloride
Featured
|
Acebutolol HCl is a cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action. |
|
| DC11648 |
2-D08
Featured
|
A cell permeable, mechanistically unique inhibitor of protein sumoylation. |
|
| DC20340 |
Chromeceptin
Featured
|
A cell-permeable benzochromene that selectively impairs the viability and growth of IGF2-overexpressing hepatocellular carcinoma cells, binds to MFP-2, stimulates the expression of IGFBP-1 and SOCS-3 through activation of STAT6. |
|
| DC23206 |
Bax inhibitor peptide V5
Featured
|
A cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. |
|
| DC22378 |
DPH
Featured
|
A cell-permeable, small-molecule c-Abl kinase activator with pEC50 of 6.1(EC50=794 nM). |
|
| DC24193 |
BAPTA
Featured
|
BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. |
|
| DC22344 |
Novaluron
Featured
|
A chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators.. |
|
| DC24086 |
Azimilide
Featured
|
Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. |
|
| DC6912 |
Ethofibrate
Featured
|
A combination of clofibrate and niacin, used to treat hyperlipidaemias |
|
| DC22904 |
VPC 23019
Featured
|
A competitive S1P receptor antagonist with pKi of 7.86 and 5.93 for S1P1 and S1P3, respectively, in radioligand binding assay. |
|
| DC22948 |
RU-TRAAK-2
Featured
|
RU-TRAAK-2 is a completely reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2). |
|
| DC23260 |
NPD4456
Featured
|
A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages.. |
|
| DC22569 |
BTTAA
Featured
|
BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF. |
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