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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC4668 Sdz Ser 082 Fumarate Selective 5-HT2B/2C receptor antagonist
DCC4669 sdz-285604 Novel inhibitor of sterol 14a-demethylases (CYP51)
DCC4670 Sdz-lap-977 Potent antiproliferative agent, binding to the “colchicine binding site” on tubulin and inhibiting tubulin polymerization in vitro
DCC4671 sdz-nkt343 Highly selective human tachykinin NK1 receptor antagonist
DCC4672 Secologanate Natural plant growth inhibitor
DCC4673 Seco-rapamycin Ethyl Ester Novel open-ring metabolite of rapamycin derivative
DCC4674 Securinine Mononitrate Antagonist of gamma-aminobutyric acid A (GABA A ) receptor and cholinergic agent
DCC4675 Seh/ache Inhibitor 12c Novel Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
DCC4676 Seh-in-12 Novel potent inhibitor of the enzyme soluble epoxide hydrolase (sEH)
DCC4677 Sempai Novel AkaLumine analog, acting asa NIR emission luciferin with the enhanced solubility in water
DCC4678 Sen205a Novel S100B inhibitor
DCC4679 Sen461 Novel Wnt inhibitor/Axin stabilizer
DCC4680 Sen-826 Novel potent antagonist of the Hedgehog pathway
DCC4681 Senp1-in-8e Sentrin-specific protease 1 (SENP1) inhibitor
DCC4682 Se-nsaid-8 Novel selenium-nonsteroidal anti-inflammatory drug (Se-NSAID), inhibiting colorectal cancer (CRC) growth via the inhibition of the cell cycle in G1 and G2/M phases and reduces the cell cycle markers like cyclin E1 and B1 in a dose dependent manner
DCC4683 Sephin1 Hydrochloride Selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A) that prolong the benefit of eIF2α phosphorylation, thereby protecting cells from proteostatic defects
DCC4684 Ser@tpp@cur Novel mitochondrial KIM-1 receptor modulator to be specifically internalized by renal tubular epithelial cells via KIM-1 receptor-mediated endocytosis and then actively distributed in mitochondria under the effect of TPP, effectively ameliorating injured
DCC4685 Sert Inhibitor 69419 Novel serotonin reuptake inhibitor
DCC4686 Sertaconazole Cytochrome P450 14α-demethylase inhibitor, also acting as a BuChE-IDO1 inhibitor
DCC4687 Setastine Highly selective H1 receptor antagonist
DCC4688 Sethrrs Inhibitor 36j The first-in-class triple-site aaRS inhibitor, targeting Salmonella enterica threonyl-tRNA synthetase (SeThrRS) with IC 50 = 19 nM and K d = 35.4 nM
DCC4689 Setin-1 The most potent inhibitor of Set7, inhibiting the KMTase G9a
DCC4690 Trichomonacid Novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro
DCC4691 Seviteronel Novel potent CYP17 lyase inhibitor, inhibiting androgen production without mineralocorticoid excess or cortisol depletion
DCC4692 sew05920 Novel telomerase inhibitor
DCC4693 Sew-05929 The First potent SecA inhibitor
DCC4694 Sf-1-087 Potent and selective STAT5 inhibitor
DCC4695 Sf-22 (npy Y2 Antagonist) Potent, selective, and highly brain-penetrant NPY Y2 receptor antagonist
DCC4696 Sf2535 Novel dual inhibitor of BRD4 and PI3K, inhibiting BRD4, PI3Kα, PI3Kδ, and PI3Kγ with IC 50 values of 277, 714, 27, and 1170 nM, respectively
DCC4697 Sfom-0046 Novel anticancer agent, arresting cell cycle in S-phase and causes DNA replication stress leading to the phosphorylation of H2AX into gamma-H2AX

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