| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC5448 | vu0403602 | Novel Positive Allosteric Modulator (PAM) of the Metabotropic Glutamate Receptor 5 (mGlu5) |
|
| DCC5449 | Vu0404251 | Highly potent non-MPEP site metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM) |
|
| DCC5450 | Vu0409775 | Muscarinic antagonist; inhibiting ACh-induced Ca(2+) responses at rat M(1-5) receptor subtypes |
|
| DCC5451 | Vu0410150 | Novel positive allosteric modulator (PAM) of mGlu4 |
|
| DCC5452 | Vu0413144 | Allosteric modulator of the M2/5 muscarinic acetylcholine receptor |
|
| DCC5453 | vu0415248 | Highly M1-selective antagonist |
|
| DCC5454 | Vu0415371 | Novel M4 muscarinic acetylcholine receptor modulator |
|
| DCC5455 | Vu0415374 | Novel mGlu4 positive allosteric modulator (PAM) |
|
| DCC5456 | Vu0431316 | Novel negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety |
|
| DCC5457 | vu0448350-1 | Highly selective muscarinic M1 PAM |
|
| DCC5458 | vu0452865 | Selective orthosteric M1 antagonist |
|
| DCC5459 | Vu0453379 | Novel, CNS Penetrant Glucagon-Like Peptide 1 Receptor (GLP-1R) Positive Allosteric Modulator (PAM) |
|
| DCC5460 | Vu0462054 | Novel potent and selective metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM) |
|
| DCC5461 | vu0463841 | Potent and selective mGlu5 negative allosteric modulator (NAM) |
|
| DCC5462 | Vu0477886 | Novel potent mGlu4 PAM with an attractive DMPK profile, and robust efficacy in preclinical Parkinsons disease model, haloperidol-induced catalepsy (HIC) |
|
| DCC5463 | Vu0486321 | mGlu1 positive allosteric modulator (PAM) |
|
| DCC5464 | Vu0487836 | Novel cyclooxygenase-1 (COX-1)-selective inhibitor |
|
| DCC5465 | vu573 Hydrochloride | Novel modulator of mammalian inward rectifying potassium (Kir) channels |
|
| DCC5466 | Vu6001192 | Novel selective negative allosteric modulator (NAM) of metabotropic glutamate receptor subtype 2 |
|
| DCC5467 | Vu6004909 | Novel potent and highly selective mGlu1 PAM (22nM), reducing striatal DA release in vivo and displaying antipsychotic efficacy |
|
| DCC5468 | Vu6007705 | Novel Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) |
|
| DCC5469 | Vu6008555 | Novel Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) |
|
| DCC5470 | Vu6009453 | Novel M4 positive allosteric modulator (PAM) |
|
| DCC5471 | Vu6009833 | Novel CNS penetrant pan-muscarinic antagonist |
|
| DCC5472 | Vu6013429 | Novel PAM of Group III (mGlu4/6/7/8) mGlu receptors |
|
| DCC5473 | Vu6017587 | Novel selective mGlu3 NAM, showing efficacy in tail suspension, elevating zero maze and marble burying, suggesting selective inhibition of mGlu3 affords anxiolytic-like and antidepressant-like phenotypes in mice |
|
| DCC5474 | Vu6027459 | First-in-class selective mGlu7 positive allosteric modulator (PAM), displaying CNS penetration in both mice (Kp = 2.74) and rats (Kp= 4.78) |
|
| DCC5475 | Vuf 5681 Dihydrobromide | Potent histamine H3 receptor silent antagonist |
|
| DCC5476 | Vuf10132 | Novel full inverse agonist at CXCR3 N3.35A |
|
| DCC5477 | vuf10148 | Potent H4R ligand |
|
