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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC5628 Zinc17043486 Novel CDK6 inhibitor
DCC5629 Zinc17167211 Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)
DCC5630 Zinc20531199 Novel EGFR triple mutant T790M/C797S allosteric inhibitor
DCC5631 Zinc27905174 Novel GDNF Family Receptor Agonist
DCC5632 Zinc32540717 Potent Ebolavirus (EBOV) Inhibitor
DCC5633 Zinc36617540 Novel Nef Protein Inhibitor; Anti-HIV
DCC5634 Zinc4085554 Novel blocker of AKT1-FAK interaction, reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation
DCC5635 Zinc50166190 Novel Zika virus RNA polymerase inhibitor
DCC5636 Zinc63908257 Novel CtpF inhibitor, inhibiting Ca -dependent ATPase activity in Mtb membrane vesicles
DCC5637 Zinc64700951 Novel gp120 of HIV-1 Antagonist
DCC5638 Zinc65022200 Novel potent and specific inhibitor of the UNC119-Src interaction, binding to UNC119 in cells, and inducing redistribution of Src to endomembranes and reduction of activating Src autophosphorylation on Y419
DCC5639 Zinc69811181 Novel ASCT2 inhibitor
DCC5640 Zinpyr-1 Cell-permeable fluorometric zinc sensor
DCC5641 Zk187638 Non-competitive AMPA receptor antagonist
DCC5642 Zk230211 Type III progesterone receptor antagonist with enhanced antiproliferative properties
DCC5643 Zk-304709 Novel oral multitarget tumour growth inhibitor
DCC5644 Zk-806450 Novel potent inhibitor of factor Xa (FXa)
DCC5645 Zl006-05 Novel dual mordulator of nNOS-PSD-95 interaction and GABA A receptor
DCC5646 Zl0513 Novel potent and selective BRD4 bromodomain 1 (BD1) inhibitor
DCC5647 Zl0516 Novel potent and selective BRD4 bromodomain 1 (BD1) inhibitor
DCC5648 Zl3138 Novel β-catenin/B-cell lymphoma 9 (BCL9) inhibitor, disrupting the β-catenin/BCL9 protein-protein interaction (PPI) with a Ki of 0.96 μM and without affecting the β-catenin/E-cadherin interaction in living cells, displaying good selectivity for β-catenin/
DCC5649 Zld10a Novel potent and highly selective inhibitor of wild-type and mutant versions of EZH2
DCC5650 Zm-181037 ATP-sensitive potassium channel-blocker; Eukalemic diuretic
DCC5651 zm-189154 Non-steroidal pure antioestrogen
DCC5652 zm-230487 5-Lipoxygenase (5-LO) inhibitor
DCC5653 Zm-244085 K-Channel opener (PCO) activating predominantly KATP channels in vitro to relax bladder detrusors
DCC5654 zm-253270 Selective nonpeptide, NK-2 receptor (NK-2R) antagonist
DCC5655 Zm-260384 Potassium channel opener
DCC5656 Zm39923 Hydrochloride Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3)
DCC5657 Zn-htsm Novel antidiabetic agent for the treatment of type 2 diabetes mellitus (DM)

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