DCC5658 |
Zofenoprilat |
Inducer of functional angiogenesis through increased H 2 S availability |
|
DCC5659 |
Zolantidine Dimaleate |
Potent, selective, and brain penetrating H2 receptor antagonist |
|
DCC5660 |
Zoledronate Disodium |
Inhibitor of osteoclastogenesis and macrophage recruitment, decreasing bone turnover and stabilizing the bone matrix, exhibiting diverse anti-tumor effects in osteosarcoma |
|
DCC5661 |
Zolimidine |
Gastroprotective agent for the treatment of peptic ulcer |
|
DCC5662 |
Zp1-12cl |
Novel zinc sensor with a chloroalkane linker, reacting specifically with the engineered protein HaloTag, binding zinc ions with a threefold fluorescence enhancement |
|
DCC5663 |
Ztb23(r) |
The first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor |
|
DCC5664 |
Ztz240 |
Novel potentiator of KCNQ2 potassium channels |
|
DCC5665 |
Zu-4280011 |
Novel COX-2 inhibitor |
|
DCC5666 |
Zuclopenthixol Dihydrochloride |
Antagonist of D1 and D2 dopamine receptors. |
|
DCC5667 |
Z-wehd-fmk |
Potent, cell-permeable and irreversible caspase-1/5 inhibitor |
|
DCC5668 |
Zwittermicin A |
Natural antibiotic, having diverse biological activities including broad-spectrum antibiosis against Bacteria and lower Eukarya, plant disease suppression, and enhancement of the insecticidal activity of Bacillus thuringiensis toxin against lepidopteran l |
|
DCC5669 |
Zwm026 |
Novel multi-target inhibitor, harboring selectivity of inhibiting EGFR T790M sparing wild-type EGFR |
|
DCC5670 |
Zxh-1-161
Featured
|
Novel Selective Degrader of GSPT1 |
|
DCC5671 |
Zx-j-19j |
Novel inhibitor of Cyclophilin J (CyPJ) PPIase, demonstrating remarkable inhibition of tumor cell growth, comparable to CsA but much stronger than 5-fluorouracil |
|
DCC5672 |
Zx-j-19l |
Novel inhibitor of Cyclophilin J (CyPJ) PPIase, demonstrating remarkable inhibition of tumor cell growth, comparable to CsA but much stronger than 5-fluorouracil |
|
DCC5673 |
Zxx2-77 |
Cyclooxygenase-1 inhibitor |
|
DCC5674 |
Zydpla1 |
Novel next generation orally active DPP-4 inhibitor to treat Type 2 Diabetes |
|
DCC5675 |
Zyj-25e |
Novel histone deacetylase inhibitor (HDACi) with potent oral antitumor activities |
|
DCC5676 |
Zyj-34c |
Novel histone deacetylase inhibitor (HDACi) with potent oral antitumor activities |
|
DCC5677 |
Zyj-34v |
Oral active histone deacetylase inhibitor with potent antitumor activity |
|
DCC5678 |
Zyz-803 |
Novel slow H2S-NO-releasing hybrid, attenuating cardiac dysfunction after heart failure |
|
DC65802 |
KT-621 |
a STAT6 degrader for multiple immune-mediated diseases. |
|
DC65821 |
Upadacitinib hemihydrate
Featured
|
Upadacitinib (ABT-494) is a potent and selective Janus kinase (JAK) 1 inhibitor with an IC50 of 43 nM, being developed for the treatment of several autoimmune disorders. |
|
DC65830 |
1-M-PES(1-Methoxy-5-methylphenazinium ethyl sulfate)
Featured
|
1-m-PES is an electron mediator which has higher stability of solutions than 1-Methoxy PMS. The stability in neutral to alkali conditions has been extremely improved with 1-Methoxy PES. 1-M-PES is a stable small-molecular compound and it has an equal or higher thermal stability than diaphorase. The 1-Methoxy PES solution can be stored long term. |
|
DC65839 |
MC1 Precursor
Featured
|
Precursor of MC1, which is a selective and potent inhibitor for COX-2, used as the radioligands for development as clinically useful PET radioligands. |
|
DC65841 |
MC1
Featured
|
MC1 is a selective and potent inhibitor for COX-2, and [11C]MC1 detected COX-2 in nonhuman primates after intracerebral injection of an inflammogen. |
|
DC60559 |
PT-179
Featured
|
PT-179 is a new orthogonal immunomodulatory drug (IMiD) derivative that binds CRBN but does not induce degradation of off-target proteins. PT-179 potently degrades proteins fused to SD40 at either the N or C terminus. |
|
DC72914 |
UE2343 |
UE2343 (UE-2343, Xanamem) is a potent, orally bioavailable, brain penetrant 11β-HSD1 inhibitor with IC50 of 24 nM in cell-free assays, with no activity for isozyme 11β-HSD2. |
|
DC72915 |
AM4085 |
AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM. |
|
DC72916 |
BB2-50F |
BB2-50F is a bactericidal inhibitor of M. tuberculosis with MIC value of 8 uM (H37Rv), inhibits succinate dehydrogenase and the F1Fo-ATP synthase. |
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