| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73801 | Faznolutamide | Faznolutamide is a potent, selective androgen receptor (AR) antagonist. |
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| DC73802 | JJ-450 | JJ-450 is a novel analogue of IMTPPE and direct and specific inhibitor of androgen receptor (AR) transcriptional activity, blocks AR recruitment to androgen-responsive elements and suppresses AR target gene expression. |
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| DC73803 | M17-B15 | M17-B15 is a potent, specific small molecule inhibitor of androgen receptor (AR) targeting the dimer interface pocket (DIP), inhibits AR transcriptional inhibition with IC50 of 0.03 uM. |
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| DC73804 | MK-0773 Featured | MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM. |
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| DC73805 | SC428 | SC428 (SC-428) is a small molecule androgen receptor (AR) signaling inhibitor, directly binds to the AR N-terminal domain (NTD) and exhibits pan-AR inhibitory effect. |
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| DC73806 | UT-105 | UT-105 is a small-molecule, irreversible, selective androgen receptor (AR) degrader (SARD) and irreversible inhibitor, binds to AR N-terminal domain (NTD) and inhibits both the AR and AR splice variants (AR-SVs). |
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| DC73807 | UT-215 | UT-215 (UT215) is a small-molecule selective androgen receptor (AR) irreversible covalent antagonist, covalently and selectively bind to C406 and C327 in the AF-1 region of AR. |
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| DC73808 | GDU-952 | GDU-952 is a novel small molecule aryl hydrocarbon receptor (AhR) agonist, activates and induces nuclear translocation of AhR. |
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| DC73809 | ITE Featured | A endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro. |
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| DC73810 | D089 | D089 is a selective small molecule stabilizer of the MYC G4-quadruplex, not only inhibits MYC expression in myeloma cell lines, but also selectively induces G1 arrest in MYC-driven cancer cell lines containing the MYC-G4 sequence. |
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| DC73811 | Isopomiferin | Isopomiferin is a prenylated isoflavonoid, collapses the tumor checkpoint module (TCM) and suppresses both MYCN and TEAD4 in MYCN-amplified NBL cells. |
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| DC73812 | KSI-3716 | KSI-3716 is a small molecule c-MYC inhibitor that blocks c-MYC/MAX binding to target gene promoters, inhibits c-MYC mediated transcriptional activity at concentrations as low as 1 uM. |
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| DC73813 | MYRA-B | MYRA-B (NSC45641) is a small molecule that induces Myc-dependent apoptosis without affecting Myc transactivation or Myc/Max DNA binding. |
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| DC73814 | NSC13728 | NSC13728 is a specific small molecule stabilizer of the Max homodimer inhibiting Myc function, also inhibits Myc-Max heterodimerization. |
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| DC73815 | NSC13728 hydrochloride | NSC13728 hydrochloride is a specific small molecule stabilizer of the Max homodimer inhibiting Myc function, also inhibits Myc-Max heterodimerization. |
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| DC73816 | VPC-70619 | VPC-70619 (VPC70619) is a selective small-molecule inhibitor of N-Myc transcription in NMYC transcription inhibition assays. |
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| DC73817 | ATF3W-aeg peptide Featured | ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages. |
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| DC73818 | CIDD-0149897 | CIDD-0149897 is a potent, selective, brain permeable estrogen receptor beta (ERβ) agonist, 40-fold selective over ERα. |
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| DC73820 | SLU-PP-332 Featured | SLU-PP-332 is a potent, selective pan ERRα/β/γ agonist with EC50 of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, in full-length ERR cell-based cotransfection/reporter assays. |
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| DC73821 | SLU-PP-915 | SLU-PP-915 is a potent pan-ERR (Estrogen-related receptor) nuclear receptor agonist with EC50 of 414/435/378 nM for ERRα/ERRβ/ERRγ, respectively. |
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| DC73822 | SMIP34 | SMIP34 (Small Molecule Inhibitor of PELP1 34) is a first-in-class, small molecule inhibitor of estrogen receptor (ER) coregulator PELP1, binds to (Kd=37.4 uM) and reduces PELP1 oncogenic functions. |
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| DC73823 | X15695 | X15695 is a potent, selective and orally active estrogen receptor alpha (ERα) degrader, destabilizes ERα and stabilizes p53, inhibits ER+ breast cancer cell growth. |
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| DC73824 | eEF2K degrader C1 | eEF2K degrader C1 is a small-molecule degrader of eEF2K, acts a molecular glue to enhance the interaction of eEF2K with the ubiquitin E3 ligase βTRCP, thereby promoting the proteasomal degradation of eEF2K. |
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| DC73825 | MG-002 | MG-002 is a potent, second-generation, orally bioavailable eIF4A RNA helicase inhibitor, potently inhibits cap-dependent mRNA translation with IC50 of 43 nM. |
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| DC73826 | RBF197 | RBF197 (RBF-197) is a novel highly potent and selective eIF4A inhibitor, inhibits human eIF4A helicase activity with IC50 of 55.2 pM. |
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| DC73827 | SBI-0498 | SBI-0498 (SBI-0730498) is a small molecule inhibitor of coronaviruses translation initiation complex 4F (eIF4F), disrupts eIF4F complex formation and inhibits coronavirus RNA and protein levels. |
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| DC73828 | SBI-5844 | SBI-5844 (SBI-1275844) is a small molecule inhibitor of coronaviruses translation initiation complex 4F (eIF4F), disrupts eIF4F complex formation and inhibits coronavirus RNA and protein levels. |
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| DC73829 | HPG1860 | HPG1860 is a potent, selective, nonbile acid full FXR agonist with EC50 of 5 nM and 18 nM in FR-FRET and luciferase assays, respectively. |
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| DC73830 | ID166 | ID119031166 (ID166) is a novel potent, selective FXR agonist with EC50 of 3 nM and 5 nM in TR-FRET FXR co-activator assay and FXR reporter assay, respectively. |
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| DC73831 | MET409 | MET409 (MET-409) is a potent, selective farnesoid X receptor (FXR) agonist with EC50 of 16 nM (human FXR). |
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