Cat. No. | Product name | CAS No. |
DC20405 |
HG-7-27-01
HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases.. |
1135270-45-9 |
DC21379 |
HG-7-92-01(NG25)
Featured
HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.. |
1315355-93-1 |
DC26060 |
gly-arg p-nitroanilide dihydrochloride
Featured
H-Gly-Arg-pNA is a colorimetric substrate for thrombin. |
125455-61-0 |
DC20406 |
HIF2α-IN-2
HIF2α-IN-2 is a potent, selective, allosteric inhibitor of HIF-2α PAS-B domain with Kd of 81 nM, shows high selectivity and does not affect HIF-1 function. |
1422955-31-4 |
DC7148 |
LY 379268
Featured
Highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. |
191471-52-0 |
DC20083 |
H-Ile-Pro-Pro-OH
H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides. |
26001-32-1 |
DC23298 |
Hinokitiol
Hinokitiol (4-Isopropyltropolone. |
499-44-5 |
DC23710 |
Hippuristanol
Hippuristanol is a potent, steroid inhibitor of eukaryotic initiation factor 4A (eIF4A), results in cell cycle arrest at G1 phase, and induces caspases activation and apoptosis. |
80442-78-0 |
DC23258 |
HIV-1 inhibitor 18A
HIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry, specifically inhibits the entry of a wide range of HIV-1 isolates with mean IC50 of 6.4 uM. |
331261-50-8 |
DC9473 |
HIV-1 integrase inhibitor
HIV-1 integrase inhibitor ((Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid) is uesful for anti-HIV. |
544467-07-4 |
DC23263 |
HIV-1 Integrase Inhibitor 7
HIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 0.58 uM, antiviral activity EC50 of 0.76 uM.. |
1235379-91-5 |
DC9472 |
HIV-1 integrase inhibitor 2
HIV-1 integrase inhibitor, in the treatment of human immunodeficiency virus (HIV) infection. |
957890-42-5 |
DC21116 |
HJC0197
Featured
HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP. |
1383539-73-8 |
DC21118 |
HJC 0726
HJC 0726 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor, inhibits cAMP-mediated EPAC2 GEF activity with IC50 of 1.0 uM. |
1449764-45-7 |
DC10626 |
HJC0152
HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor with remarkably improved aqueous solubility. |
1420290-99-8 |
DC21117 |
HJC-0338
HJC-0338 is a potent and specific EPAC2 antagonist with IC50 of 0.4 uM for competing with 8-NBD-cAMP in binding EPAC2. |
1417718-39-8 |
DC11366 |
HKI 357
HKI 357 is an irreversible dual inhibitor of the EGF receptor tyrosine kinases EGFR and HER2 (IC50s = 34 and 33 nM, respectively). |
848133-17-5 |
DC21119 |
HL001
HL001 (HL 001) is a potent cyclophilin A (CypA) inhibitor with IC50 of 31.6 nM, induces NSCLC cell cycle arrest and apoptosis via restoring p53 expression. |
1186371-31-2 |
DC21977 |
HlyU inhibitor CM14
HlyU inhibitor CM14 (1025E12) is a specifc, small-molecule inhibitor of transcriptional regulator HlyU activity with EC50 of 30.97 uM, inhibits HlyU from binding to target DNA by covalently modifying Cys30. |
588678-13-1 |
DC10414 |
HM30181(Encequidar)
Featured
HM30181 is a potent and selective inhibitor of P-glycoprotein. |
849675-66-7 |
DC12074 |
HM30181 mesylate
Featured
HM30181 mesylate is a competitive and potent P-glycoprotein inhibitor. |
849675-87-2 |
DC8768 |
HMN-214
Featured
HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM. |
173529-46-9 |