Cat. No. | Product name | CAS No. |
DC21310 |
ML115
ML115 is a novel "bone-seeking" bisphosphonate based MMP-2 specific inhibitor (BMMPI), spares the activity of other MMPs including MMP-9. |
1314124-91-8 |
DC20896 |
ML119
ML119 (CID1357397. |
1815600-05-5 |
DC21370 |
ML132
ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases.. |
1230628-71-3 |
DC23652 |
ML133
ML133 (CID781301) is a potent, selective K(ir)2.1 potassium channel with IC50 of 1.8 uM at pH 7.4 and 290 nM at pH 8.5, respectively. |
185669-79-8 |
DC23653 |
ML133 hydrochloride
ML133 (CID781301) is a potent, selective K(ir)2.1 potassium channel with IC50 of 1.8 uM at pH 7.4 and 290 nM at pH 8.5, respectively. |
1222781-70-5 |
DC8594 |
ML167
ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B. |
1285702-20-6 |
DC22668 |
ML-184
ML-184 (ML184) is a potent, selective GPR55 agonist with EC50 of 263 nM, >120-fold, 83-fold, and 57-fold selectivity against GPR35, CB1 and CB2. |
794572-10-4 |
DC22156 |
ML-191
Featured
ML-191 is a potent, selective GPR55 antagonist with 160 nM potency for GPR55 and >100-fold selectivity against GPR35, CB1 and CB2. |
931695-79-3 |
DC22155 |
ML193
ML193 (CID 1261822) is a potent, selective GPR55 antagonist with IC50 of 221 nM, shows >27-, >145- and >145-fold selectivity for GPR55 over CB1, GPR35 and CB2, respectively. |
713121-80-3 |
DC21371 |
ML197
ML197 is a potent, selective small molecule inhibitor of Cdc2-like kinases (CLK) and DYRK with IC50 of 96/40/206 nM for CLK1/CLK4/Dyrk1A, respectively. |
1222891-88-4 |
DC7683 |
ML-228
ML-228 is a hIF pathway activator (EC50 values are 1.23 and 1.4 μM for HRE gene reporter assay and HIF-1α nuclear translocation assay respectively); acts via chelation of iron, independently of PHD. |
1357171-62-0 |
DC7942 |
ML-265
Featured
ML-265 activates tumor-specific PKM2 (EC50 = 92 nM) by binding to the dimer-dimer interface between two subunits of PKM2 and inducing tetramerization. |
1221186-53-3 |
DC21319 |
ML 278
Featured
ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM. |
1604821-43-3 |
DC21320 |
ML 279
ML279 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 17 nM. |
1604821-55-7 |
DC20077 |
ML-290
ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM. |
1482500-76-4 |
DC20898 |
ML298
Featured
ML298 is a potent, selective phospholipase PLD2 inhibitor with IC50 of 355 nM, displays >53-fold selectivity over PLD1 (IC50>20 uM). |
1426916-02-0 |
DC21806 |
ML-299
Featured
ML299 is a potent, CNS penetrant, dual phospholipase PLD1/PLD2 probe with IC50 of 6 nM/20 nM, respectively. |
1426916-00-8 |
DC12222 |
ML311
Featured
ML311 is a potent and selective inhibitor of the Mcl-1/Bim interaction. |
315698-17-0 |
DC21314 |
ML316
ML316 is a specific antifungal agent that fungal-selectively inhibits the mitochondrial phosphate carrier Mir1, exhibits potent antifungal activity against the moderatelyazole-resistant C. albicans strain CaCi-2 with MIC of 0.05 ug/ml. |
1604819-70-6 |
DC26087 |
ML350
ML350 (CYM 50202) is a highly potent and selective Opioid kappa receptor (OPRK1/KOR) antagonist with IC50 of 9-16 nM. |
1565852-90-5 |
DC21809 |
ML352
ML352 (VU-0476201) is a potent, selective choline transporter (CHT) inhibitor with Ki of 92 nM. |
1649450-12-3 |
DC21804 |
ML354
ML354 (VU0099704) is a novel potent and selective PAR4 antagonist with IC50 of 140 nM, displays 71-fold selectivity versus PAR-1. |
89159-60-4 |