Cat. No. | Product name | CAS No. |
DC11971 |
NAV-2729(Grassofermata)
Featured
NAV 2729 (NAV2729) is a chemical potentiator for mRNA-LNPs, increasing the delivery efficiencies of mRNA-LNPs in vitro and in vivo. NAV 2729 (NAV2729) is a novel, direct and selective small molecule inhibitor of small GTPase ARF6 with IC50 of 1.5 uM in nucleotide exchange assays. |
419547-11-8 |
DC20472 |
Naxillin
Featured
Naxillin is the first non-auxin-like molecule that promotes root branching, activates a subset of auxin-induced transcripts, including AUX/IAA, SAUR and PIN families; induces auxin response in the basal meristem; represents a valuable tool to further decipher the molecular networks involved in lateral root branching. |
301176-96-5 |
DC21362 |
NBC19
NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.. |
2068818-75-5 |
DC9476 |
NBD-556
Featured
NBD-556 is small molecule mimetic of CD4, NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. |
333353-44-9 |
DC9477 |
NBD-557
NBD-557 is a potentially HIV-1 inhibitor. |
333352-59-3 |
DC7209 |
NBI42902
NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm). |
352290-60-9 |
DC23638 |
NBQX disodium
NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM. |
479347-86-9 |
DC21364 |
NC-001
Featured
NC-001 (NC 001, NC001, az-NC-001) is a potent, specific, cell-permeable inhibitor of immunoproteasome caspase-like sites (β1i and β1), does not correlate with inhibition of chymotrypsin-like sites.. |
1237540-68-9 |
DC21366 |
NC-043
NC-043 (15-Oxospiramilactone) is a diterpenoid derivative inhibitor of Wnt/β-catenin signaling that interferes with the β-catenin/TCF4 association. |
1053172-87-4 |
DC23377 |
NCD-25
NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO.. |
1456972-46-5 |
DC23353 |
NCD-38
NCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO (IC50>100 uM). |
2078047-42-2 |
DC21369 |
NCGC 00067819
Featured
NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay. |
847163-23-9 |
DC23699 |
NCGC00071837
NCGC00071837 (PDE4-IN-5A) is a potent, selective PDE4 inhibitor with IC50 of 24 and 18 nM for PDE4A and PDE4D, respectively, weak inhibition for PDE4B (IC50=0.54 uM) and inactive for PDE1/3/5/7/9/10/11. |
578747-98-5 |
DC21372 |
NCGC00185684
NCGC00185684 (ML154) is a potent, selective, brain penetrant NPSR (Neuropeptide S receptor. |
1345964-89-7 |
DC8857 |
NCT-501
NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. |
1802088-50-1 |
DC23741 |
NCT-502
NCT-502 is a small molecule 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3.7 uM) that reduces the production of glucose-derived serine in cells and suppress the growth of PHGDH-dependent cancer cells. |
1542213-00-2 |
DC21387 |
NCX-4016
NCX-4016 (Nitroaspirin. |
175033-36-0 |
DC23681 |
ND-654 (ND654)
ND-654 (ND654) is a novel potent, liver-specific acetyl-CoA carboxylase (ACC) inhibitor with IC50 of 3/8 nM for human ACC1/ACC2, respectively. |
1434641-55-0 |
DC10302 |
N-deacetylated BMS-202
N-deacetylated BMS-202 is the deacetylated of BMS-202. BMS-202 is an inhibitor of the PD-l/PD-Ll interaction, mainly used for cancer treatment. |
|
DC9347 |
N-desmethyl Enzalutamide
Featured
N-desmethyl Enzalutamide(N-desmethyl MDV3100) is a major metabolite of Enzalutamide, Enzalutamide(MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM. |
1242137-16-1 |
DC10438 |
N-Desmethylclozapine
Featured
N-Desmethylclozapine is a dengue virus inhibitor, and an agonist of δ-opioid receptor. |
6104-71-8 |
DC21374 |
NDT 9513727
NDT 9513727 is a potent, selective and orally bioavailable C5a receptor inverse agonist with IC50 of 11.6 nM in radioligand binding assay. |
439571-48-9 |