Cat. No. | Product name | CAS No. |
DC23393 |
BETi-211
A novel potent small-molecule BET bromodomain (BRD) inhibitor that binds to BET proteins with Ki values of <1 nM. |
1995867-02-1 |
DC11995 |
BI 703704
A novel potent soluble guanylate cyclase (sGC) activator. |
1423067-48-4 |
DC11880 |
TH1834
A novel potent specific histone acetyltransferaseTip60 inhibitor. |
2108830-08-4 |
DC11881 |
TH1834 dihydrochloride
A novel potent specific histone acetyltransferaseTip60 inhibitor. |
2108830-09-5 |
DC22798 |
ADA-07
A novel potent TOPK inhibitor that effectively suppresses SUV-induced activation of MAPKs signal transduction resulting in reduced SUV-induced skin carcinogenesis. |
|
DC11603 |
SR-19871
A novel potent ULK1 inhibitor with IC50 of 11 nM.. |
|
DC11693 |
AJS1669 sodium
A novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM. |
|
DC11692 |
AJS1669
A novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM. |
1853130-05-8 |
DC21354 |
MT47-100
A novel potent, allosteric, simultaneously direct activator and inhibitor of AMPK complexes containing the β1 or β2 isoform, respectively. |
1179347-23-9 |
DC23525 |
AAT-008
A novel potent, and selective prostaglandin EP4 receptor antagonist with binding IC50 of 2.4 nM. |
847727-81-5 |
DC22688 |
AZD 3676
A novel potent, combined serotonin 5-HT1A and 5-HT1B receptor antagonist with Ki of 0.13 and 2.4 nM in brain homogenates, respectively. |
1259929-13-9 |
DC11986 |
OX03050
A novel potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM. |
1357581-47-5 |
DC20692 |
ASP 8477
A novel potent, highly selective fatty acid amide hydrolase (FAAH) inhibitor with IC50 of 0.99, 1.65 and 57.3 nM for human FAAH-1, FAAH-1 (P129T) and FAAH-2, respectively. |
906737-25-5 |
DC21507 |
PHA-408
A novel potent, highly selective, ATP-competitive IKK-2 inhibitor with IC50 of 40 nM, 350-fold selectivity over IKK-1. |
503555-55-3 |
DC23309 |
BCL6 inhibitor 8c
A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays. |
2130878-25-8 |
DC21209 |
KW-2581
A novel potent, irreversible and orally active inhibitor of steroid sulfatase (STS) with IC50 of 13 nM in ZR-75-1 cells. |
284045-56-3 |
DC11769 |
MPO-IN-28
Featured
A novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM. |
37836-90-1 |
DC21058 |
GNS-1481
A novel potent, irreversible, T790M mutant-selective inhibitor of mutant EGFR with IC50 of 6.2, 3.4 and 4.2 nM for L858R-T790M, T790M and Del19-T790M, respectively. |
1903008-81-0 |
DC21059 |
GNS-1486
A novel potent, irreversible, T790M mutant-selective inhibitor of mutant EGFR with IC50 of 8.3, 4.2 and 4.3 nM for L858R-T790M, T790M and Del19-T790M, respectively. |
1903008-85-4 |
DC11612 |
KBP-7018 hydrochloride
A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively. |
1613437-67-4 |
DC11611 |
KBP-7018
A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively. |
1613437-66-3 |
DC11751 |
UHC1
A novel potent, non-agonist PPARγ ligand that blocks CDK5-mediated PPARγ phosphorylation, without the classical agonism. |
1629960-95-7 |