Cat. No. | Product name | CAS No. |
DC10157 |
PAβN dihydrochloride
Featured
PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor. |
100929-99-5 |
DC22190 |
PBF509
PBF509 (PBF-509, NIR 178) is a novel selective and potent Adenosine A2A Receptor (A2AR) antagonist, antagonizes A2AR agonist-mediated cAMP accumulation and impedance responses with KB values of 72.8 and 8.2 nM, respectively. |
|
DC11100 |
PBI-4050 sodium
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
1254472-97-3 |
DC11099 |
PBI-4050
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
1002101-19-0 |
DC22191 |
PBT434
Featured
PBT434 is a novel quinazolinone compound with effect of lowering cellular iron levels, prevents iron mediated neurodegeneration and α-synuclein toxicity in multiple models of Parkinson disease; inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein, a protein that aggregates in the neuropathology; prevents loss of substantia nigra pars compacta neurons (SNpc), lowers nigral α-synuclein accumulation, and rescues motor performance in mice model of PD. |
1232841-78-9 |
DC21459 |
PC1244
PC1244 is a long acting fungicidal azole that targets A. fumigatus CYP51A and CYP51B, inhibits ergosterol synthesis in A. fumigatus with IC50 of 8 nM. |
2046185-88-8 |
DC21460 |
PC945
PC945 is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively. |
1931946-73-4 |
DC23061 |
L-45
PCAF BRD inhibitor L-45 is a potent, selective, and cell-active PCAF bromodomain inhibitor with Ki of 47 nM in HTRF assays, >4,500-fold selectivity over BRD4. |
2079885-05-3 |
DC23651 |
PCARBTP
PCARBTP is a derivative, potent, specific Kv1.3 channel inhibitor, reduces cell viability and efficiently kills B16F10 cancer cells at 1 uM. |
2176486-23-8 |
DC11169 |
PCC0104005
PCC0104005 (PCC-0104005) is a novel modulator of serotonin, dopamine, and noradrenaline receptors, including partial agonism at dopamine D2, D3, D4, serotonin 5-HT1A, and 5-HT2A receptors and antagonism at 5-HT2B, 5-HT6, and 5-HT7 receptors. |
1708960-04-6 |
DC12080 |
PCI-33380
PCI-33380 is an irreversible Bruton's Tyrosine Kinase (BTK) inhibitor (fluorescent probe). |
1022899-36-0 |
DC10531 |
PCO371
Featured
PCO371 is a novel, orally active small molecule that acts as a full agonist of PTHR1. |
1613373-33-3 |
DC23759 |
PCSK9 modulator 10
PCSK9 modulator 10 is a highly potent, orally active PCSK9 modulator that inhibits PCSK9 production in HepG2 cells with IC50 of 0.036 nM. |
1874254-18-8 |
DC23758 |
PCSK9-IN-7l
PCSK9-IN-7l is a potent, small molecule PCSK9 mRNA translation inhibitor with IC50 of 1.37 uM, shows limited bone marrow toxicity (IC50=27.1 uM).. |
1632250-31-7 |
DC7224 |
PD 123319
Featured
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
136676-91-0 |
DC21466 |
PD166285
Featured
PD166285 (PD 0166285) is a broad-spectrum receptor tyrosine kinase (RTK) inhibitor that inhibits PDGFR-β, EGFR, and FGFR1 and c-Src with IC50 of 7-85 nM. |
212391-63-4 |
DC12316 |
PD-168077 maleate
Featured
PD-168077 maleate is a selective dopamine D4 receptor agonist, with a Ki of 9 nM. |
630117-19-0 |
DC7571 |
PD173955
Featured
PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. |
260415-63-2 |
DC12219 |
PD1-IN-2
PD1-IN-2 is a PD1 signaling pathway inhibitor, which acts as an immunomodulator. |
1673534-97-8 |
DC21936 |
PD1-PD L1 inhibitor Polaris
PD1-PD L1 inhibitor Polaris is a novel potent, small molecule inhibitor of PD-1/PD-L1 interaction (IC50=0.1-10 nM in ELISA assays) with anti-cancer activity. |
2201132-36-5 |
DC8744 |
PD318088
Featured
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. |
391210-00-7 |
DC21467 |
PDD 00017273
PDD 00017273 is the first-in-class, selective inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with Kd, biochemical EC50 of 1.45 nM, 26 nM. |
1945950-21-9 |