Cat. No. | Product name | CAS No. |
DC9911 |
Pulsatilla saponin D(SB365)
Pulsatilla saponin D(SB365) isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer. |
68027-15-6 |
DC23274 |
Purfalcamine
Featured
Purfalcamine is a potent, specific inhibitor of Plaasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) with IC50 of 17 nM. |
1038620-68-6 |
DC8558 |
Puromycin aminonucleoside
Featured
Puromycin Aminonucleoside (3'-Amino-3'-deoxy-N6,N6-dimethyladenosine) is the aminonucleoside portion of the antibiotic puromycin. |
58-60-6 |
DC10169 |
Puromycin
Featured
Puromycin is an aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. It is a protein synthesis inhibitor. |
53-79-2 |
DC23344 |
PVZB-1194
PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM. |
1141768-04-8 |
DC26129 |
PWT143 (ME-401)
Featured
PWT143 (ME-401), is an orally bioavailable inhibitor of the delta isoform of phosphatidylinositide 3-kinase (PI3K), with potential antineoplastic activity. |
1595129-71-7 |
DC23657 |
PWZ-029
PWZ-029 is a potent, subtype-selective partial inverse agonist of α5 GABAA receptors with Ki of 30 nM, demonstrates memory enhancing effects in vivo. |
164025-33-6 |
DC20222 |
Px-104
Px-104(Px-102) is a farnesoid X receptor (FXR) agonist potentially for the treatment of non-alcoholic fatty liver disease. |
1268244-88-7 |
DC7992 |
PX 12
Featured
PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1(Trx-1) currently in clinical development as an antitumor agent; IC50=7 uM in Hela, MTT assay, 72 h. |
141400-58-0 |
DC10565 |
PX-102(PX-20606)
PX20606, also known as PX-102, is a FXR agonist. |
1268244-85-4 |
DC20519 |
Pyk2-IN-25a
Pyk2-IN-25a is a highly potent Pyk2 (PTK2B) inhibitor with IC50 of 0.67 nM, dispalys 2-fold weakening potency for FAK (IC50=1.26 nM). |
2052970-45-1 |
DC23668 |
PyP-1
PyP-1 is a potent, highly selective, and orally bioavailable PDE10A inhibitor with Ki of 0.23 nM. |
1370527-16-4 |
DC9636 |
Pyr6
Pyr6 is a selective inhibitor of TRPC3 with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells). |
245747-08-4 |
DC22202 |
Pyrazinib
Pyrazinib (Pyrazinib (P3)) is a pyrazine phenol small molecule drug with anti-angiogenic and anti-metabolic activity in-vivo in zebrafish and in-vitro isogenic models of OAC radioresistance. |
200417-97-6 |
DC20154 |
Pyridoxine hydrochloride
Featured
Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. |
58-56-0 |
DC20520 |
Pyrimidinone 8
Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM. |
65004-42-4 |
DC21547 |
Pyrimidyn 7
Pyrimidyn 7 is a potent, dual-action dynamin GTPase activity inhibitor with IC50 of 1.1 uM/1.8 uM for dynamin I/dynamin II respectively, competitively inhibits both GTP and phospholipid interactions with dynamin. |
1440126-94-2 |
DC12084 |
Pyronaridine tetraphosphate
Featured
Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against drug resistant Plasmodium falciparum, P. vivax, P. ovale and P. malariae. |
76748-86-2 |
DC23125 |
Pyrotinib maleate
Featured
Pyrotinib maleate (SHR-1258 maleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50 of 13/38 nM, respectively. |
1397922-61-0 |
DC20521 |
Pyrrophenone
Pyrrophenone is a potent cPLA2α inhibitor with enzyme IC50 of 4.2 nM. |
341973-06-6 |
DC9430 |
PYZD-4409
PYZD-4409 is a novel small molecule inhibitor of Ubiquitin-activating enzyme UBA1/E1 enzyme with an IC50 of 20 uM (cell-free enzymatic assay). |
423148-78-1 |
DC22197 |
PZ09(PKC-9)
Featured
PZ09 (PKC-zeta inhibitor 9, PKC-ζ inhibitor PZ9) is a potent, isoform selective PKC-zeta (PKC-ζ) inhibitor with IC50 of 5.18 nM, displays excellent selectivity (>200-fold) over other PKC isoforms with exception of PKC-i (10-fold). PZ09 also shows high selectivity for CDK-2 (>200-fold), as well as a broader range of other kinases (<50% inhibition at 10 uM). PZ09 is a small-molecule inhibitor, the first tool to successfully interrogate aPKC signaling in cells. |
1132609-87-0 |