Cat. No. | Product name | CAS No. |
DC10290 |
PZM21
Featured
PZM21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM. |
1997387-43-5 |
DC22203 |
Q151
Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (MtbIMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity. |
2226449-95-0 |
DC11290 |
QC-3611
Featured
QC-3611 is a selective inhibitor of JARID1A/1B, which is a target existing in various tumors (JARID1A IC50 = 13 nM ;JARID1B IC50 = 2 nM). QC-3611 is promisingly to be used as an antineoplastic drug. |
1613410-75-5 |
DC21548 |
QC-6352
QC-6352 is a potent and selective KDM4 family inhibitor with IC50 of 104, 56, 35, and 104 nM for KDM4A, KDM4B, KDM4C, and KDM4D, respectively. |
1851373-36-8 |
DC11041 |
QCA276
QCA276 is a novel potent BET proteins inhibitor with IC50/Ki of 10/.3 nM, QCA276 is the BET ligand for PROTAC QCA570. |
2126819-40-5 |
DC11040 |
QCA570
QCA570 is a novel, highly potent efficacious BET degrader (PROTAC). |
2207569-08-0 |
DC12585 |
TB47
Featured
QcrB inhibitor TB47 (TB47) is a novel antimycobacterial agent that fuctions as a putative respiratory complex III (QcrB) inhibitor with MIC of 0.016-0.5 ug/mL against a panel of 56 M. tuberculosis clinical isolates. |
1799682-71-5 |
DC21549 |
QD 232
QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation, decreasing pancreatic cancer cell viability and migration. |
1527467-32-8 |
DC21550 |
QD 325
QD325 is a potent redox modulator that induces Nrf2-mediated oxidative stress and unfolded protein responses in PDAC cells (IC50=0.9 uM). |
2132410-88-7 |
DC7747 |
QL-IX-55
QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively |
1223002-54-7 |
DC20522 |
QL-X-138
QL-X-138 is a selective and potent BTK/MNK dual kinase inhibitor with IC50 of 8, 107.4, and 26 nM for BTK, MNK1, and MNK2, respectively. |
1469988-63-3 |
DC12556 |
QM31
QM31 (SVT016426, Apaf-1 inhibitor QM31) is a cytoprotective agent that inhibits the formation of the apoptosome (IC50=7.9 uM in vitro), the caspase activation complex composed by Apaf-1, cytochrome c, dATP and caspase-9. |
937735-00-7 |
DC11478 |
QM385
QM385 is a highly potent small molecule SPR inhibitor,that inhibits the BH4 pathway, blocking T cell proliferation and autoimmunity. |
2296727-52-9 |
DC12605 |
QO IIR
QO IIR is a reversible, tight-binding inhibitor inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 320 nM. |
150404-10-7 |
DC5139 |
QS 11 (QS11,BML-WN117)
QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. |
944328-88-5 |
DC11160 |
Qstatin
Featured
QStatin is a novel, potent, and selective Vibrio quorum sensing (QS) inhibitor, shows pan-QS inhibitor activity in diverse Vibrio species. |
902688-24-8 |
DC22204 |
QTX125
QTX125 (QTX-125) is a novel potent, selective HDAC6 inhibitor, displays excellent selectivity over other HDACs. |
1279698-31-5 |
DC8691 |
Quetiapine sulfoxide dihydrochloride
Quetiapine Sulfoxide is a metabolite of Quetiapine. Quetiapine is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and along with an antidepressant to treat major depressive disorder. |
329218-11-3 |
DC9916 |
Quillaic acid(Quillaja sapogenin)
Featured
Quillaic acid(Quillaja sapogenin) is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol; can elicit dose-dependent antinociceptive effects in two murine thermal models. |
631-01-6 |
DC20523 |
Quinalizarin
Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM. |
81-61-8 |
DC24047 |
Quizartinib hydrochloride
Featured
Quizartinib (AC220) is a potent, selective, second-generation FLT3 inhibitor with Kd of 1.6 nM, inhibits Wt FLT3 and FLT3-ITD autophosphorylation in MV4-11cell with IC50 of 4.2 and 1.1 nM, respectively. |
1132827-21-4 |
DC10401 |
R121919
Featured
R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types. |
195055-03-9 |