DC90061 |
Vx-445(r) |
Less active enantiomer of Elexacaftor |
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DC90062 |
(-)-5-hydroxy-equol |
Natural microbial metabolite of isoflavone genistein, increasing the lifespan and improving the thermal and oxidative stress tolerance of C. elegans |
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DC90063 |
(-)-adenophorine |
Moderate alpha-l-fucosidase inhibitor |
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DC90064 |
(-)-agelastatin A |
Inhibitor of Eukaryotic Translation; Antitumor Natural Product |
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DC90065 |
(-)-antofine |
Antitumor agent to be associated with negative regulation of Met endosomal signaling in renal cancer cells |
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DC90066 |
(-)-astercin |
Novel inhibitor of cholesterol transport proteins |
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DC90067 |
(-)-cm-tpmf |
Subtype-selective activator of K(Ca)2.1 |
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DC90068 |
(-)-gomisin M1 |
Natural modulator of miRNA biogenesis, inhibiting the proliferation, migration, and invasion of hepatocellular carcinoma (HCC) cells |
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DC90069 |
(-)-oxfbd05 |
Novel potent inhibitor of the CREBBP/EP300 bromodomain, showing >100-fold selectivity over a representative member of the BET bromodomains, BRD4(1) |
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DC90070 |
(-)-tetrabenazine
Featured
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Inhibitor of VMAT-2, decreasing monamines into synaptic vesicles |
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DC90071 |
(+)-calanolide A |
Novel non-nucleoside reverse transcriptase inhibitor (NNRTI) |
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DC90072 |
(+)-clausenamide |
Natural inhibitor of hepatocyte ferroptosis, protecting against drug-induced liver injury |
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DC90073 |
(+)-isocorydine Hydrochloride |
Natural inhibitor of ERK signaling pathways, inhibiting epithelial-mesenchymal transition via STAT3, showing the growth inhibition of HepG2, HeLa and MGC-803 cancer cell lines |
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DC90074 |
(+)-jnj-bj |
Novel TNKS/2 inhibitor, competing with nicotinamide binding to tankyrases |
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DC90075 |
(+)-mesembrine |
Natural highly potent inhibitor of the serotonin transporter (SERT) |
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DC90076 |
(+)-nd |
Novel BRD4 inhibitor, suppressing osteoclastogenesis and ovariectomized osteoporosis by blocking RANKL-mediated MAPK and NF-κB pathways |
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DC90077 |
(+)-sattabacin |
Antiviral activity against Varicella Zoster |
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DC90078 |
(+)-sj311 |
Novel potent anti-malarial agent against multiple resistant strains of P. falciparum in vitro and show no cytotoxicity to mammalian cells |
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DC90079 |
(+)-tetrabenazine |
Catecholamine-depleting agent, actively against the 3 major monoamines in the CNS |
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DC90080 |
(+)-xylariamide A |
Novel probe for mycobacterial and fungal carbonic anhydrase |
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DC90081 |
(+/-)-marmesin |
Novel angiogenesis inhibitor, regulating endothelial cell fate and angiogenesis |
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DC90083 |
(±)-a-278637 |
Novel potassium channel opener |
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DC90084 |
(±)-clopidogrel Hydrogensulfate |
Inhibitor of ADP-induced platelet aggregation; anti-thrombotic |
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DC90085 |
(±)-doi Hydrochloride |
Potent and selective 5-HT2 serotonin receptor agonist |
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DC90086 |
(±)-gc242 |
Novel profluorescent RAMOSUS3 (RMS3) probe with strigolactone-like bioactivity |
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DC90087 |
(±)-mrjf22 |
Novel prodrug of the sigma (σ) ligand haloperidol metabolite II conjugated with the histone deacetylase (HDAC) inhibitor valproic acid, demonstrating antiangiogenic activity |
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DC90088 |
(1r,2r)-ifenprodil |
Potent antagonist of GluN2B-NMDA receptors (Ki = 5.8 nM), inhibiting ion flux in two-electrode voltage clamp experiments (IC50 = 223 nM) |
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DC90089 |
(1r,3r)-rsl3 |
Negative control for RSL3 |
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DC90090 |
(1s,2s)-cyclopropane-1,2-dicarboxylic Acid |
Building Block |
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DC90091 |
(2,6-aza)trp |
Novel water-sensitive probe, demonstrating superior sensitivity for detecting modulation of water microsolvation, structural conformation during oligomer formation and 5FUrd binding to both wild type and mutant SOD1 |
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