DCC0815 |
avβ5 Inhibitor 12 |
The first potent and selective αvβ5 integrin inhibitor |
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DCC0816 |
Awd-12-281 |
Novel PDE4 inhibitor |
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DCC0817 |
Aws-i-169 |
Novel specific inhibitor of HIV-1 entry through interaction with the Env spike by virtue of the incorporation of a guandinium group |
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DCC0818 |
Ax1/mer-in-1 |
Novel potent dual inhibitor of Ax1 and Mer |
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DCC0819 |
Ax-10479 |
Zn -dependent inhibitor of human plasma Lp-PLA2 |
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DCC0820 |
Ax14373 |
Highly specific JNK inhibitor #212121; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0 |
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DCC0821 |
Ax15839 |
Novel dual ERK5 and BRD4 inhibitor |
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DCC0822 |
Ax15892 |
Novel potent and selective ERK5 inhibitor |
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DCC0823 |
Ax15910 |
Novel potent dual ERK5 and BRD4 inhibitor |
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DCC0824 |
Axl-in-13c |
Novel highly potent and orally bioavailable Axl inhibitor |
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DCC0825 |
Axt050 |
Novel integrin-binding peptide, inhibiting hepatocyte growth factor (HGF) signaling through Met-integrin interactions, also being an antiangiogenic agent by reducing phosphorylation of VEGR2, IGFR, and PDGFR, stabilizing vessels by disrupting α5β1 signali |
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DCC0826 |
ay-30068 |
Cyclooxygenase Inhibitor; |
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DCC0827 |
az1136 |
Second Generation |
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DCC0828 |
Az11760788 |
Novel transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist |
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DCC0829 |
Az12048189 |
Novel transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist |
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DCC0830 |
Az12080282 Dihydrochloride |
Novel orally bioavailable inhibitor of Hedgehog signaling |
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DCC0831 |
Az12099548 |
Novel transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist |
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DCC0832 |
Az12489875-002 |
Novel potent EphB4 inhibitor |
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DCC0833 |
Az1366 |
Novel tankyrase inhibitor, enhancing irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance |
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DCC0834 |
Az-13767370 |
Novel covalent ERK1/2 inhibitor |
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DCC0835 |
Az7188 |
Novel weak PAR2 antagonist |
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DCC0836 |
Aza197 |
Novel selective Cdc42 inhibitor, suppressing primary colon cancer growth and prolonging survival in a preclinical mouse xenograft model by downregulation of PAK1 activity |
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DCC0837 |
aza-bodipy |
Near-IR probe for detecting conformational changes of Aβ1-42 soluble oligomers in vitro |
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DCC0838 |
azadirone |
Inducer of Death Receptors and Sensitizer of Human Cancer Cells to TRAIL through a p53-Independent Mechanism |
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DCC0839 |
Azalanstat |
Inhibitor of hepatic cholesterol biosynthesis, inhibiting the cytochrome P450 enzyme lanosterol 14alpha-demethylase |
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DCC0840 |
Aza-thip |
Novel selective GABA-C antagonist |
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DCC0841 |
Azd Cxcr2 Antagonist |
Novel CXCR2 antagonist with 200 times improvement in solubility than AZD8309 |
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DCC0842 |
Azd0328 |
Selective alpha7 nicotinic receptor activator |
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DCC0843 |
Azd1386 |
Novel transient receptor potential vanilloid 1 (TRPV1) antagonist |
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DCC0844 |
Azd1897
Featured
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AZD1897 is a PIM1, PIM2, and PIM3 inhibitor with IC50 values of less than 3 nM for these three PIM kinases. AZD1897 exhibits anticancer activity and synergistically inhibits the activity of acute myeloid leukemia (AML) cells in combination with Capivasertib (HY-15431). This synergistic inhibitory effect is achieved through the inhibition of the mTOR and MCL1 pathways. |
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