DCC2647 |
Icl-sirt078 |
Novel highly selective, substrate-competitive SIRT2 inhibitor, displaying a significant neuroprotective effect in a lactacystin-induced model of Parkinsonian neuronal cell death in the N27 cell line |
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DCC2648 |
Icpd62 |
Novel inhibitor of heat shock protein 90 (Hsp90), demonstrating anticancer activity against colorectal, osteosarcoma and cervical cancer cell lines |
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DCC2649 |
Icrf-193 |
DNA topoisomerase II inhibitor |
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DCC2650 |
Ict2700 |
Potent cytotoxin selectively by CYP1A1 as a tumor-selective treatment for human bladder cancers |
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DCC2651 |
Id110460001 |
Novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist |
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DCC2652 |
Id110460002 |
Novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist |
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DCC2653 |
Id110460003 |
Novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist |
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DCC2654 |
idaverine |
M1 and M2 Antagonist |
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DCC2655 |
Ide-in-37 Tfa Salt |
Novel highly potent substrate-selective inhibitor of insulin-degrading enzyme (IDE), blocking insulin binding while allowing glucagon cleavage, even at saturating inhibitor concentrations |
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DCC2656 |
Ide-in-63 Tfa Salt |
Novel highly potent substrate-selective inhibitor of insulin-degrading enzyme (IDE), blocking insulin binding while allowing glucagon cleavage, even at saturating inhibitor concentrations |
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DCC2657 |
Idh2 Inhibitor |
Novel isocitrate dehydrogenase 2 (IDH2) mutants inhibitor for the treatment of cancer |
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DCC2658 |
Idi-3783 |
Novel mutant-selective Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor |
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DCC2659 |
Ido1/2 Inhibitor 4t |
The first inhibitor targeting both IDO1/2 that has excellent in vitro inhibitory activity (IDO1 IC50 = 28 nM and IDO2 IC50 = 144 nM) |
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DCC2660 |
idoxifene |
Selective ER modulator (SERM) |
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DCC2661 |
Idr-0081053 |
Novel bactericidal agent against M. tuberculosis under acidic conditions, being effective at sterilizing cultures in a concentration-dependent fashion at the highest concentrations |
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DCC2662 |
Idr-0099118 |
Novel concentration dependent bactericidal agent against M. tuberculosis, being markedly more efficient at killing M. tuberculosis under acidic conditions |
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DCC2663 |
Idr-1002 |
Innate Defence Regulator Peptide, Enhancing Monocyte Migration and Adhesion on Fibronectin |
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DCC2664 |
Idr-1018 Tfa Salt |
Novel immunomodulatory and antibiofilm innate defense regulator peptide |
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DCC2665 |
Idrapril |
Angiotensin converting enzyme (ACE) inhibitor |
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DCC2666 |
Iferanserin |
Selective serotonin 5-HT2A receptor antagonist |
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DCC2667 |
Ifn-1 Inducer C3 |
Novel Type I Interferon Inducer |
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DCC2668 |
Ifn-1 Inducer E51 |
Novel Type I Interferon Inducer |
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DCC2669 |
Ifn-1 Inducer L56 |
Novel Type I Interferon Inducer; Intercalator of DNA; Inhibitor of the retrovirus replications including HIV |
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DCC2670 |
Igf2bp2/imp2 Inhibitor 4 |
First Small-Molecule Inhibitor of RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy |
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DCC2671 |
Igf2bp2/imp2 Inhibitor 6 |
Novel Inhibitor of RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy |
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DCC2672 |
Igf2bp2/imp2 Inhibitor 9 |
Novel Inhibitor of RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy |
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DCC2673 |
Iglu-antagonist-21a |
Highly potent fluorescent iGlu receptor antagonist |
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DCC2674 |
Ihr-saha |
Novel dual SMO-HDAC antagonist, retaining similar specificity for SAHA-targeted HDACs, disabling deviant Hedgehog signaling and preventing GLI binding to DNA |
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DCC2675 |
Ikarugamycin |
Natural Inhibitor of Clathrin-Mediated Endocytosis |
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DCC2676 |
Ikkß-in-124 |
Novel allosteric inhibitor of IκBα phosphorylation and NF-κB transcriptional activity through selective capture of the inactive conformation and hence blockade of IKKβ S177/S181 phosphorylation |
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