| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC2676 | Ikkß-in-124 | Novel allosteric inhibitor of IκBα phosphorylation and NF-κB transcriptional activity through selective capture of the inactive conformation and hence blockade of IKKβ S177/S181 phosphorylation |
|
| DCC2677 | Ilmofosine | Antineoplastic phospholipid, being effective against many tumor types, including ovary, non-small cell lung, kidney, and melanoma, exhibiting competitive inhibition of protein kinase C (PKC) activity |
|
| DCC2678 | Iloperidone Hydrochloride | Dual D 2 /5-HT 2 antagonist as an antipsychotic agent |
|
| DCC2679 | Imarikiren Dihydrochloride | Novel orally effective direct renin inhibitor for treating diabetic nephropathy and hypertension |
|
| DCC2680 | Imb-xma0038 | Novel anti-tuberculosis agent, targeting Mycobacterial tuberculosis (Mtb) aspartate semialdehyde dehydrogenase |
|
| DCC2681 | Imb-yh-8 | Novel inhibitor of protein kinase B (PknB), inhibiting PknB auto-phosphorylation and the phosphorylation of GarA by PknB in a dose-dependent manner |
|
| DCC2682 | Imc-48 | BCL2 i-motif-interactive compound, stabilizing or facilitating the folding of the i-motif |
|
| DCC2683 | Imc-76 | BCL2 i-motif-interactive compound, destabilizing or unfolding the i-motif |
|
| DCC2684 | Imidacloprid | Insect neurotoxin, blocking nicotinic acetylcholine receptors and preventing acetylcholine from transmitting impulses between nerves |
|
| DCC2685 | Imm-h004 | Novel potent inhibitor of BV2 microglia activation, protecting PC12 cells and primary neurons against indirect toxicity mediated by exposure to conditioned medium (CM) from LPS-treated BV2 cells |
|
| DCC2686 | Imp-1002 | Novel resistance breaking antimalarial N-myristoyltransferase (NMT) inhibitor, binding to NMT peptide binding pocket |
|
| DCC2687 | Imp-1700 | Novel cell-active and potent inhibitor of bacterial DNA repair, potentiating quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus |
|
| DCC2688 | Imp2070 | Novel Probe for NLRP3 Inflammasome Inhibitor MCC950 |
|
| DCC2689 | Impdh-in-1 | First in-class allosteric inhibitor of a bacterial IMPDH, showing to counteract the activation by the natural positive effector, MgATP, and to block the enzyme in its apo conformation |
|
| DCC2690 | Imprimatin-c1 | Novel plant immune-priming agent, acting as a partial agonist of salicylic acid |
|
| DCC2691 | Imprimatin-c2 | Novel plant immune-priming agent, acting as a partial agonist of salicylic acid |
|
| DCC2692 | Imt007 | Mtb growth inhibitor, inhibiting Mtb GlgB activity by interacting to its active site residues |
|
| DCC2693 | In-1130 | Potent inhibitor of the TGF-β type I receptor activin receptor-like kinase 5 (ALK5) |
|
| DCC2694 | In-1166 | Novel ALK5 inhibitor |
|
| DCC2695 | Incb018424 Racemic | Janus-associated kinase (JAK) inhibitor |
|
| DCC2696 | Incb059872 Tosylate | Novel potent and selective lysine-specific demethylase 1 (LSD1) inhibitor |
|
| DCC2697 | Ind-07 | Novel selective Mtb-DHFR inhibitor as an antimycobacterial agent |
|
| DCC2698 | Ind31119 | Novel selective inhibitor of PfHsp90, bypassing its highly similar human orthologs |
|
| DCC2699 | Ind45193 | Antiprion agent, reducing PrP(Sc) levels in dividing and stationary-phase cells |
|
| DCC2700 | Indazole-cl | Selective estrogen receptor modifier (SERM), being a selective ERß agonist |
|
| DCC2701 | Indeloxazine Hydrochloride | Antidepressant and cerebral activator, acting as a serotonin releasing agent, norepinephrine reuptake inhibitor, and NMDA receptor antagonist, enhancing acetylcholine release via activation of the 5-HT4 receptor |
|
| DCC2702 | Indimitecan Hydrochloride | Topoisomerase I (Top1) inhibitor |
|
| DCC2703 | Indobufen | Platelet aggregation inhibitor acting as a reversible Cyclooxygenase>cyclooxygenase inhibitor |
|
| DCC2704 | Indole-3-lactic Acid | Metabolite of tryptophan, reducing the interleukin-8 (IL-8) response after IL-1β stimulus, interacting with the transcription factor aryl hydrocarbon receptor (AHR) and preventing transcription of the inflammatory cytokine IL-8, being anti-inflammatory in |
|
| DCC2705 | Indolmycin | Natural antibiotic, selectively inhibiting bacterial tryptophanyl-tRNA synthetase (TrpRS) |
|
