DCC3187 |
Ly-395153 |
Allosteric modulator of AMPA receptors |
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DCC3188 |
Ly444711 |
Orally active ghrelin agonist, bindjng with high affinity to and being a potent activator of the growth hormone secretagogue receptor 1a (GHS-R1a) receptor |
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DCC3189 |
Ly451646 |
AMPA receptor potentiator |
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DCC3190 |
Ly456236 Hydrochloride |
Selective mGlu1 receptor antagonist |
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DCC3191 |
Ly-465608 |
Novel potent and selective dual PPARalpha/gamma agonist |
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DCC3192 |
Ly-466195 |
Novel competitive GLUK5 receptor antagonist |
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DCC3193 |
Ly544344 |
Prodrug of LY354740, highly selective and potent agonist of group II mGlu receptors (mGluR2) |
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DCC3194 |
Ly-580276 |
Novel inhibitor of the type I transforming growth factor beta receptor (TβRI) |
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DCC3195 |
Lyc-31138 |
Novel F1F0-ATPase modulator, significantly decreasing M2 glutamate and increasing M4 glutamate |
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DCC3196 |
Ly-hn2am |
Nove fluorescent probe for highly sensitive monitoring drug induced lysosomal pH value changes, exhibiting good biological compatibility, low cytotoxicity and high resistance to photobleaching |
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DCC3197 |
Lyngbyastatin 7 |
Natural Potent Marine-Derived Elastase Inhibitor |
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DCC3198 |
Lysine Orotate |
Inhibitor of viral replication, especially useful in the treatment of the Herpes family of viruses which includes Herpes Simplex 1 and 2 , EBV , CMV and Varicella. |
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DCC3199 |
Lyso-7 |
Inhibitor of cyclooxygenase (COX); Pan partial agonist of PPARγ, PPARα and PPARβ/δ |
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DCC3200 |
Lzz-02 |
Novel inhibitor of the transcriptional activity of β-catenin, degrading the expression of β-catenin by stabilizing axin 2 and diminishing downstream proteins levels, including c-Myc and cyclin D1, effectively shrinking tumor xenograft derived from colonic |
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DCC3201 |
M-084 Hydrochloride |
TRPC4/5 channel blocker, exhibiting antidepressant and anxiolytic effects |
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DCC3202 |
M1-pam-a |
Novel selective muscarinic M1 receptor positive allosteric modulator, significantly improved scopolamine-induced cognitive deficits without prominent signs of diarrhea at up to 1000 mg/kg in mice |
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DCC3203 |
M1-pam-b |
Novel selective muscarinic M1 receptor positive allosteric modulator, showed both significant improvement of scopolamine-induced cognitive deficits and severe diarrhea |
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DCC3204 |
M4k2009
Featured
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M4K2209 is a potent, selective BMP type I receptor ALK2 inhibitor with IC50 of 9 nM, >180-fold selective over ALK5 (IC50=2427 nM). |
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DCC3205 |
M4k2127 |
Novel potent and selective ALK2 inhibitor, showing high initial brain uptake, including in the region of interest (pons) |
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DCC3206 |
M4k2163 |
Novel CNS Penetrant ALK2 Inhibitor for the Treatment of Diffuse Intrinsic Pontine Glioma |
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DCC3207 |
M-5mpep |
Partial antagonist of mGlu5 |
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DCC3208 |
M7594_0037 |
Novel Peptide Deformylase (PDF) Inhibitor, having inhibitory activity against HeLa, A549 and MCF-7 |
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DCC3209 |
Mac-0547630 |
Novel potent and selective inhibitor of UppS without off-target effects on membrane potential |
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DCC3210 |
Mac13243 |
Novel inhibitor of the bacterial lipoprotein targeting chaperone, LolA |
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DCC3211 |
Macluraxanthone |
Natural immunomodulator, significantly decreasing TNF-α and IL-10 cytokine production, regulating the NF-κB and MAPK signaling pathways, displaying the strongest antiproliferative effects with IC50 values of 2.84 and 0.95 μM against A431 and HeLa cancer c |
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DCC3212 |
Madtp-372 |
Potent and selective inhibitor of the induction of cytopathic effect by CHIKV and VEEV |
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DCC3213 |
Madurmycin |
Polyether ionophore antibiotic, inhibiting proliferation and induces apoptosis in myoblast cells |
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DCC3214 |
Magl-2102 |
Novel reversible monoacylglycerol lipase (MAGL) inhibitor |
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DCC3215 |
Magnesium L-threonate |
Inhibitor of TNF-α, preventing and restoring memory deficits associated with neuropathic pain |
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DCC3216 |
Magnesium Oxaloacetate |
Inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O2 |
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